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T73331GSK3-IN-3；化合物GSK3-IN-3GSK3-IN-3
GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy. GSK3-IN-3 is non-ATP and non-substrate competitive and neuroprotective against 6-OHDA.
价 格：￥电议型 号：T73331产 地：中国大陆
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T73326CB2R-IN-3；化合物 CB2R-IN-3CB2R-IN-3
CB2R-IN-3 is a selective antagonist of cannabinoid type 2 receptor (CB2R) . CB2R-IN-3 has high affinity for human CB2R and specific selectivity for CB1R. CB2R-IN-3 can be combined with CB65 , the activator of CB2R. CB2R-IN-3 effectively up-regulates the expression of anti-inflammatory cytokines and down-regulates the expression of pro-inflammatory cytokines [1] .
价 格：￥电议型 号：T73326产 地：中国大陆
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T73306TrkA-IN-3；化合物 TrkA-IN-3TrkA-IN-3
TrkA-IN-3 is a potent, subselective, and allosteric inhibitor of TrkA, demonstrating significant potency with an IC50 of 22.4 nM. It exhibits over 8000-fold selectivity towards TrkA in comparison to TrkB and TrkC, making it a valuable compound for pain research.
价 格：￥电议型 号：T73306产 地：中国大陆
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T73305ALR2-IN-3；化合物 ALR2-IN-3ALR2-IN-3
ALR2-IN-2, a potent aldose reductase (ALR2) inhibitor, demonstrates IC50 values of 22 nM for rat ALR2 and 116 nM for ALR1, respectively. This compound is utilized in diabetic complications research.
价 格：￥电议型 号：T73305产 地：中国大陆
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T73298MurA-IN-3；化合物 MurA-IN-3MurA-IN-3
MurA-IN-3, a reversible pyrrolidinedione-based MurA inhibitor, exhibits an IC50 of 4.5 μM against MurA and demonstrates antibacterial activity [1].
价 格：￥电议型 号：T73298产 地：中国大陆
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T73292ZIKV-IN-3；化合物 ZIKV-IN-3ZIKV-IN-3
ZIKV-IN-3, a derivative of andrographolide, serves as a potent inhibitor of the Zika virus (ZIKV) NS5 methyl transferase (MTase), showcasing an IC50 of 18.34 μM. It effectively curtails ZIKV replication and infection, making it valuable in Zika virus research.
价 格：￥电议型 号：T73292产 地：中国大陆
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T73283HBV-IN-32；化合物 HBV-IN-32HBV-IN-32
HBV-IN-32, a potent inhibitor of covalently closed circular DNA (cccDNA), exhibits significant anti-Hepatitis B Virus (HBV) activity by achieving an IC50 of 0.14 ?M against HBsAg. Additionally, it impedes cell growth.
价 格：￥电议型 号：T73283产 地：中国大陆
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T73282HBV-IN-31；化合物 HBV-IN-31HBV-IN-31
HBV-IN-31, a potent inhibitor of covalently closed circular DNA (cccDNA), demonstrates significant anti-HBV activity by inhibiting cell growth and exhibiting an IC50 value of 0.13 ?M for HBsAg.
价 格：￥电议型 号：T73282产 地：中国大陆
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T73281HBV-IN-30；化合物 HBV-IN-30HBV-IN-30
HBV-IN-30 (ex44), a flavone derivative, acts as a potent inhibitor of covalently closed circular DNA (cccDNA), which is essential for viral RNA transcription and subsequent viral DNA production. This compound shows promise for researching hepatitis B virus (HBV) infection.
价 格：￥电议型 号：T73281产 地：中国大陆
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T73262C5aR-IN-3；化合物 C5aR-IN-3C5aR-IN-3
C5aR-IN-3, a potent C5aR inhibitor, holds potential for inflammation disease research due to its ability to counteract increased C5a levels, which are linked to autoimmune and inflammatory disorders.
价 格：￥电议型 号：T73262产 地：中国大陆
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T73244NSD3-IN-3；化合物 NSD3-IN-3NSD3-IN-3
NSD3-IN-3, a potent inhibitor of NSD3, demonstrates significant anticancer activity by inhibiting the growth and proliferation of the non-small cell lung cancer cell line H460, with an IC50 value of 1.86 μM.
价 格：￥电议型 号：T73244产 地：中国大陆
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T73223NS5A-IN-3；化合物 NS5A-IN-3NS5A-IN-3
NS5A-IN-3 (Compound 15) serves as a potent NS5A inhibitor, displaying exceptionally high efficacy against HCV genotype 1b, enhanced activity towards genotype 3a (GT 3a), and substantial metabolic stability. It also demonstrates a superior resistance barrier compared to daclatasvir in genotype 1b [1].
价 格：￥电议型 号：T73223产 地：中国大陆
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T73186HPK1-IN-31；化合物 HPK1-IN-31HPK1-IN-31
HPK1-IN-31 inhibitor with an IC 50 value of 0.8 nM. HPK1-IN-31 has anti-tumour activity and has great potential for immunotherapy [1] .
价 格：￥电议型 号：T73186产 地：中国大陆
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T73185PRMT6-IN-3；化合物PRMT6-IN-3PRMT6-IN-3
PRMT6-IN-3 is a selective PRMT6 inhibitor with an IC50 value of 192 nM.PRMT6-IN-3 has anticancer activity and induces apoptosis in cancer cells.
价 格：￥电议型 号：T73185产 地：中国大陆
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T73149HPK1-IN-33；化合物 HPK1-IN-33HPK1-IN-33
HPK1-IN-33 (compound 21), a Hematopoietic Progenitor Kinase 1 (HPK1) inhibitor, exhibits a high potency with a K_i of 1.7 nM. It effectively inhibits IL-2 production, demonstrating EC_50 values of 286 nM in Jurkat WT cells and >10000 nM in Jurkat HPK1 KO cells [1].
价 格：￥电议型 号：T73149产 地：中国大陆
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T73143PHGDH-IN-3；化合物PHGDH-IN-3PHGDH-IN-3
PHGDH-IN-3 is an orally active phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 2.8 μM against PHGDH. PHGDH-IN-3 can be used in studies about cancer.
价 格：￥电议型 号：T73143产 地：中国大陆
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T73123ThrRS-IN-3；化合物 ThrRS-IN-3ThrRS-IN-3
ThrRS-IN-3, a threonyl-tRNA synthetase (ThrRS) inhibitor, exhibits high potency, demonstrated by an IC50 of 19 nM and a Kd of 34 nM against Salmonella enterica ThrRS. It also possesses antibacterial activities.
价 格：￥电议型 号：T73123产 地：中国大陆
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T73108EGFR-IN-30；化合物 EGFR-IN-30EGFR-IN-30
EGFR-IN-30, a potent inhibitor of EGFR, exhibits IC50 values of 1-10 nM and <1 nM for EGFR (WT) and EGFR (L858R/T790M/C797S), respectively. This compound is of potential interest for research into diseases characterized by cell proliferation, such as cancer.
价 格：￥电议型 号：T73108产 地：中国大陆
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T73039CYP1B1-IN-3；化合物 CYP1B1-IN-3CYP1B1-IN-3
CYP1B1-IN-3 is a potent, selective inhibitor of CYP1B1, exhibiting IC50 values of 6.6 nM for CYP1B1, 347.3 nM for CYP1A1, and >10000 nM for CYP1A2. It also impedes cell migration and invasion, and inhibits the P-gp, AKT/ERK, FAK/SRC, and EMT pathways [1].
价 格：￥电议型 号：T73039产 地：中国大陆
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T73027PARP-2-IN-3；PARP-2 抑制剂3PARP-2-IN-3
PARP-2-IN-3 is used as a potent PARP-2 inhibitor (IC50=0.07 μM) with anti-tumor activity that induces apoptosis and necrosis in cancer cells, and can be used for the study of breast cancer.CAS ??128-52-56-8
价 格：￥电议型 号：T73027产 地：中国大陆
