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  • T82614DAM-IN-1；化合物 DAM-IN-1DAM-IN-1

    DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM. It effectively inhibits Caulobacter growth, exhibiting a minimum inhibitory concentration (MIC) of 35 μM [1].

    价 格：￥电议型 号：T82614产 地：中国大陆

  • T82569DHX9-IN-1；化合物 DHX9-IN-1DHX9-IN-1

    DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].

    价 格：￥电议型 号：T82569产 地：中国大陆

  • T82568DHX9-IN-2；DHX9 抑制剂2DHX9-IN-2

    DHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research.

    价 格：￥电议型 号：T82568产 地：中国大陆

  • T82493EGFR/HER2/DHFR-IN-2；化合物 EGFR/HER2/DHFR-IN-2EGFR/HER2/DHFR-IN-2

    EGFR/HER2/DHFR-IN-2 (Compound 4b) serves as an inhibitor for EGFR, HER2, and DHFR, with IC50 values of 0.248, 0.156, and 0.138 μM, respectively. It exhibits anticancer activity, displaying IC50 values of 9.14, 7.33, 14.18, 24.87, 20.07, and 6.16 μM in Hep G2, HeLa, HEp-2, HCT 116, PC-3, and MCF7 cancer cell lines, respectively. Additionally, EGFR/HER2/DHFR-IN-2 has been shown to reduce the growth of breast cancer tumors [1].

    价 格：￥电议型 号：T82493产 地：中国大陆

  • T82483Elastase LasB-IN-1；化合物 Elastase LasB-IN-1Elastase LasB-IN-1

    Elastase LasB-IN-1 (Compound 4b), a potent and selective inhibitor of elastase LasB, exhibits antibacterial activity and has been determined to possess an IC50 value of 76 nM [1].

    价 格：￥电议型 号：T82483产 地：中国大陆

  • T82458Epigenetic factor-IN-1；化合物 Epigenetic factor-IN-1Epigenetic factor-IN-1

    Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7. It is utilized in the study of liver cancer [1].

    价 格：￥电议型 号：T82458产 地：中国大陆

  • T82447Ergtoxin-1；化合物 Ergtoxin-1ErgTx1；ErgTx1

    Ergtoxin-1, a potassium channel blocker isolated from the venom of the Mexican scorpion Centruroides noxius, inhibits ERG-K+ channels in nerve, heart, and endocrine cells [1].

    价 格：￥电议型 号：T82447产 地：中国大陆

  • T82421FAAH/cPLA2α-IN-1；化合物 FAAH/cPLA2α-IN-1FAAH/cPLA2α-IN-1

    FAAH/cPLA2α-IN-1 is a compound that simultaneously inhibits both FAAH and cPLA2α, demonstrating potent activity with half-maximal inhibitory concentrations (IC50s) of 32 nM for FAAH and 47 nM for cPLA2α [1].

    价 格：￥电议型 号：T82421产 地：中国大陆

  • T82393FLT3/CHK1-IN-1；化合物 FLT3/CHK1-IN-1FLT3/CHK1-IN-1

    Compound 18, also known as FLT3/CHK-IN-1, is a dual inhibitor targeting FLT3 and CHK1, exhibiting over 1700-fold selectivity towards c-KIT and significantly diminishing hERG affinity, with an IC50 of 58.4 μM. It demonstrates efficacy in suppressing tumor growth in mouse xenotransplantation models implanted with MV-4-11 cells [1].

    价 格：￥电议型 号：T82393产 地：中国大陆

  • T82374FOXM1-IN-2；化合物 FOXM1-IN-2FOXM1-IN-2

    FOXM1-IN-2, a FOXM1 inhibitor, exhibits antineoplastic activity [1].

    价 格：￥电议型 号：T82374产 地：中国大陆

  • T82361FXIIa-IN-1；化合物 FXIIa-IN-1FXIIa-IN-1

    XIIa-IN-1-IN-3 (Compound 22) is a Factor XIIa inhibitor with an apparent inhibition constant (K i app) of 97.8 nM, utilized in the study of thrombosis [1].

    价 格：￥电议型 号：T82361产 地：中国大陆

  • T82360FXIIa-IN-2；化合物 FXIIa-IN-2FXIIa-IN-2

    XIIa-IN-1-IN-2 (Compound 21) serves as a potent Factor XIIa inhibitor with an apparent inhibition constant (K i app) of 62.2 nM, utilized primarily in thrombosis research [1].

    价 格：￥电议型 号：T82360产 地：中国大陆

  • T82356GABA-IN-1；化合物 GABA-IN-1GABA-IN-1

    GABA-IN-1 (Compound 6), a GABA inhibitor, exhibits larvicidal and insecticidal properties, achieving a mortality rate of 93% at a concentration of 50 mg/L [1].

    价 格：￥电议型 号：T82356产 地：中国大陆

  • T82355GABA-IN-2；化合物 GABA-IN-2GABA-IN-2

    GABA-IN-2 (Compound 5), a GABA inhibitor, exhibits both larvicidal and insecticidal properties, achieving an 87% mortality rate at a concentration of 50 mg/L [1].

    价 格：￥电议型 号：T82355产 地：中国大陆

  • T82343Gamma-Glutamyl Transferase-IN-1；化合物 Gamma-Glutamyl Transferase-IN-1Gamma-Glutamyl Transferase-IN-1

    Gamma-Glutamyl Transferase-IN-1 (compound 4de), a β-carboline 1-hydrazide inhibitor, exhibits antifungal and antibacterial properties by targeting glutamyltransferase. Its mechanism of action involves inducing the accumulation of reactive oxygen species, disrupting cell membranes, and dysregulating histone acetylation [1].

    价 格：￥电议型 号：T82343产 地：中国大陆

  • T82342Gamma-Glutamyl Transferase-IN-2；化合物 Gamma-Glutamyl Transferase-IN-2Gamma-Glutamyl Transferase-IN-2

    Gamma-Glutamyl Transferase-IN-2 (compound 4dq), a β-carboline 1-hydrazide inhibitor, exhibits both antifungal and antibacterial properties by targeting glutamyltransferase. Its mode of action includes inducing reactive oxygen species accumulation, compromising cell membranes, and disrupting histone acetylation processes [1].

    价 格：￥电议型 号：T82342产 地：中国大陆

  • T82329GDI2-IN-1；化合物 GDI2-IN-1GDI2-IN-1

    GDI2-IN-1 (compound (+)-37), a GDP-dissociation inhibitor beta (GDI2) inhibitor, demonstrates potent inhibitory activity with an IC50 of 2.87 μM and a K D of 36 μM, and exhibits excellent in vivo antitumor efficacy in pancreatic xenograft models overexpressing GDI2 [1].

    价 格：￥电议型 号：T82329产 地：中国大陆

  • T82289Glycolate oxidase-IN-1；化合物 Glycolate oxidase-IN-1Glycolate oxidase-IN-1

    Glycolate oxidase-IN-1 (compound 26), a salicylic acid derivative, serves as an inhibitor of glycolate oxidase (GO) and exhibits an inhibitory concentration (IC50) of 38.2 μM. It is efficacious in reducing oxalate production in hyperoxaluric hepatocytes and has potential applications in researching primary hyperoxaluria type 1 (PH1) [1].

    价 格：￥电议型 号：T82289产 地：中国大陆

  • T82267GPAT-IN-1；化合物 GPAT-IN-1GPAT-IN-1

    GPAT-IN-1, a glycerol-3-phosphate acyltransferase (GPAT) inhibitor, exhibits an inhibitory concentration (IC50) of 8.9 μM and is utilized in obesity research [1].

    价 格：￥电议型 号：T82267产 地：中国大陆

  • T82235hCA/Wnt/β-catenin-IN-1；化合物 hCA/Wnt/β-catenin-IN-1hCA/Wnt/β-catenin-IN-1

    hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8 nM, respectively. Additionally, this compound attenuates P-gp activity and impedes the Wnt/β-catenin signaling pathway. Furthermore, it compromises the viability of cancer cells, specifically targeting the NCI/ADR-RES DOX-resistant cell line [1].

    价 格：￥电议型 号：T82235产 地：中国大陆

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