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  • T81850MASTL-IN-2；化合物 MASTL-IN-2MASTL-IN-2

    MASTL-IN-2 is a potent inhibitor of microtubule-associated serine/threonine kinase-like (MASTL). It demonstrates notable efficacy in suppressing the proliferation of human epithelial MIA PaCa cancer cells, exhibiting an IC50 value of 2.8 nM [1].

    价 格：￥电议型 号：T81850产 地：中国大陆

  • T81830MDM2/XIAP-IN-1；化合物 MDM2/XIAP-IN-1MDM2/XIAP-IN-1

    MDM2/XIAP-IN-1 (compound 14) is an orally active dual inhibitor of MDM2 and XIAP, exhibiting anti-cancer activity with an IC50 of 0.3 μM and potential applications in cancer research [1].

    价 格：￥电议型 号：T81830产 地：中国大陆

  • T81792Mip-IN-1；化合物 Mip-IN-1Mip-IN-1

    Mip-IN-1 (S,S-28i) is a novel inhibitor derived from rapamycin targeting the macrophage infectivity potentiator (Mip) proteins. It exhibits potent anti-enzymatic effects against Mip proteins from Neisseria meningitidis and Neisseria gonorrhoeae, significantly enhancing macrophage bactericidal efficacy [1].

    价 格：￥电议型 号：T81792产 地：中国大陆

  • T81743mTORC1-IN-1；化合物 mTORC1-IN-1mTORC1-IN-1

    mTORC1-IN-1 (T1), a rapamycin homologue (rapalog) and selective inhibitor of mTORC1, controls cell growth and metabolism, with implications in various diseases such as cancer. It interacts with mTORC1 by attaching to the FKBP12-FRB complex, evidencing a docking score of -11.6 kcal/mol [1].

    价 格：￥电议型 号：T81743产 地：中国大陆

  • T81737MurF-IN-1；化合物 MurF-IN-1MurF-IN-1

    MurF-IN-1 (Compound 7) is an inhibitor of the MurF enzyme, exhibiting an inhibitory concentration with a pIC50 value of 5.19 in assays targeting Streptococcus pneumoniae MurF [1].

    价 格：￥电议型 号：T81737产 地：中国大陆

  • T81712Naa50-IN-1；化合物 Naa50-IN-1Naa50-IN-1

    Naa50-IN-1 (Compound 4a) is a potent inhibitor of N-α-Acetyltransferase 50 (Naa50), demonstrating an IC50 of 7 mM, with potential applications in cancer research [1].

    价 格：￥电议型 号：T81712产 地：中国大陆

  • T81684Neuroinflammatory-IN-1；化合物 Neuroinflammatory-IN-1Neuroinflammatory-IN-1

    Neuroinflammatory-IN-1 (Compound 5) serves as an anti-neuroinflammatory agent, exhibiting an inhibitory effect on nitric oxide (NO) production, with an IC50 of 65.4 μM [1].

    价 格：￥电议型 号：T81684产 地：中国大陆

  • T81670NKG2D-IN-1；化合物 NKG2D-IN-1NKG2D-IN-1

    NKG2D-IN-1, also known as compound 21, is an inhibitor of the natural killer group 2D receptor (NKG2D) exhibiting inhibitory concentration 50 (IC50) values of 0.3 ?M in NKG2D/MICA TR-FRET assays and 0.7 ?M in ULBP6 TR-FRET assays [1].

    价 格：￥电议型 号：T81670产 地：中国大陆

  • T81669NKG2D-IN-2；化合物 NKG2D-IN-2NKG2D-IN-2

    NKG2D-IN-2 (compound 47) is an inhibitor of the natural killer group 2D receptor (NKG2D), demonstrating half-maximal inhibitory concentrations (IC50s) of 0.1 ?M for NKG2D/MICA and 0.2 ?M for ULBP6 in time-resolved fluorescence resonance energy transfer (TR-FRET) assays [1].

    价 格：￥电议型 号：T81669产 地：中国大陆

  • T81654NorA-IN-1；化合物 NorA-IN-1NorA-IN-1

    NorA-IN-1 (Compound 16), a NorA efflux pump inhibitor, has applications in the research of multidrug resistance [1]. It functions by impeding the NorA efflux pump in everted membrane vesicles.

    价 格：￥电议型 号：T81654产 地：中国大陆

  • T81648NOX2-IN-1；化合物 NOX2-IN-1NOX2-IN-1

    NOX2-IN-1 (compound 10) serves as an inhibitor of the enzyme nicotinamide adenine dinucleotide phosphate oxidase isoform 2 (NOX2). It specifically disrupts the p47phox-p22phox protein-protein interaction, exhibiting high binding affinities and potent activity within cellular assays [1].

    价 格：￥电议型 号：T81648产 地：中国大陆

  • T81647NOX2-IN-2；化合物 NOX2-IN-2NOX2-IN-2

    NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (K i) of 0.24 μM. It effectively suppresses reactive oxygen species (ROS) production originating from NOX2 in cellular contexts [1].

    价 格：￥电议型 号：T81647产 地：中国大陆

  • T81646NPAS3-IN-1；NPAS3制剂1NPAS3-IN-1

    NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization, which regulates NPAS3 transcription by modulating the heterodimerization of NPAS3 with ARNT at the cellular level.

    价 格：￥电议型 号：T81646产 地：中国大陆

  • T81642NS2B-NS3pro-IN-1；化合物 NS2B-NS3pro-IN-1NS2B-NS3pro-IN-1

    NS2B-NS3pro-IN-1, a potent Zika Virus NS2B-NS3 protease inhibitor, exhibits an EC50 of 50 μM and is significant in the ZIKV replication cycle [1].

    价 格：￥电议型 号：T81642产 地：中国大陆

  • T81641NS2B-NS3pro-IN-2；化合物 NS2B-NS3pro-IN-2NS2B-NS3pro-IN-2

    Compound 11, also known as NS2B-NS3pro-IN-2, functions as an inhibitor of the Zika Virus NS2B-NS3 protease and exhibits antiviral properties at a concentration of 50 μM [1].

    价 格：￥电议型 号：T81641产 地：中国大陆

  • T81630OAT1/3-IN-1；化合物 OAT1/3-IN-1OAT1/3-IN-1

    OAT1/3-IN-1 (compound 7), a dual inhibitor of OAT1 and OAT3, demonstrates the ability to mitigate the toxicity of Cys-Hg in HEK-OAT1 cells at a concentration of 10 μM and offers potential kidney protection. This compound is utilized in the investigation of mercury-induced renal damage [1].

    价 格：￥电议型 号：T81630产 地：中国大陆

  • T81629OAT1/3-IN-2；化合物 OAT1/3-IN-2OAT1/3-IN-2

    OAT1/3-IN-2 (compound 8) is a dual inhibitor of OAT1 and OAT3 that demonstrates potential protective effects against Cys-Hg toxicity in HEK-OAT1 cells (10 μM) and may safeguard renal function. This compound is useful for investigating mercury-induced nephrotoxicity [1].

    价 格：￥电议型 号：T81629产 地：中国大陆

  • T81620OfChi-h-IN-1；化合物 OfChi-h-IN-1OfChi-h-IN-1

    OfChi-h-IN-1 is a potent inhibitor of OfChi-h, exhibiting a K i value of 0.33 μM. This compound significantly suppresses the growth and development of Ostrinia nubilalis larvae and demonstrates superior insecticidal activity compared to Hexaflumuron. As such, OfChi-h-IN-1 is considered a novel candidate for an insect growth regulator [1].

    价 格：￥电议型 号：T81620产 地：中国大陆

  • T81619OfChi-h-IN-2；化合物 OfChi-h-IN-2OfChi-h-IN-2

    OfChi-h-IN-2 (compound TQ19) is a potent inhibitor of OfChi-h, exhibiting a K i of 0.33 μM, and significantly impairs the growth and development of Ostrinia nubilalis larvae. This compound is relevant for research in agricultural insecticides [1].

    价 格：￥电议型 号：T81619产 地：中国大陆

  • T81617OfHex1-IN-1；化合物 OfHex1-IN-1OfHex1-IN-1

    OfHex1-IN-1 (compound 11c), a β-N-acetylhexosaminidase from Ostrinia furnacalis inhibitor, exhibits high potency and selectivity with an IC50 of 28.1 μM and a K i of 25.6 μM. It is applicable in research for developing green pesticides related to OfHex1 [1].

    价 格：￥电议型 号：T81617产 地：中国大陆

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