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T81595OSBP-IN-1;化合物 OSBP-IN-1OSBP-IN-1
OSBP-IN-1 (compound 12), an analogue of Schweinfurthins, selectively targets oxysterol-binding protein (OSBP) and exhibits antitumor activity [1].
价 格:¥电议型 号:T81595产 地:中国大陆
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T81549Papilostatin-2;化合物 Papilostatin-2Papilostatin-2
Papilostatin-2 is an anti-angiogenic peptide utilized for research purposes in the study of angiogenesis inhibition [1].
价 格:¥电议型 号:T81549产 地:中国大陆
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T81548PAP-IN-1;化合物 PAP-IN-1PAP-IN-1
PAP-IN-1 (compound 28) is a binuclear metallohydrolase inhibitor specific to purple acid phosphatases (PAPs) with a Ki value of 168 nM against mammalian PAP and a Kic value of 0.17 μM targeting porcine PAP. This compound is significant in the research of anti-osteoporotic drug development [1].
价 格:¥电议型 号:T81548产 地:中国大陆
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T81547PAP-IN-2;化合物 PAP-IN-2PAP-IN-2
Compound 35 (PAP-IN-2) is a purple acid phosphatase (PAP) inhibitor with an inhibition constant (Ki) of 186 nM, potentially useful in the development of anti-osteoporotic compounds [1].
价 格:¥电议型 号:T81547产 地:中国大陆
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T81534PDE11A4-IN-1;化合物 PDE11A4-IN-1PDE11A4-IN-1
PDE11A4-IN-1 (compound 23b) is a potent, selective inhibitor of PDE11A4, demonstrating an IC50 of 12 nM and exhibiting high selectivity against PDE1, PDE2, PDE7, PDE8, and PDE9 [1].
价 格:¥电议型 号:T81534产 地:中国大陆
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T81528Peginterferon alfacon-2;化合物 Peginterferon alfacon-2Peginterferon alfacon-2
Peginterferon alfacon-2 is a human antibody that targets IFNAR1/2 [1].
价 格:¥电议型 号:T81528产 地:中国大陆
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T81503PEX5-PEX14 PPI-IN-2;化合物 PEX5-PEX14 PPI-IN-2PEX5-PEX14 PPI-IN-2
Compound 12, also known as PEX5-PEX14 PPI-IN-2, is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor with half-maximal effective concentration (EC50) values of 5 ?M in T. b. brucei and 17 ?M in HepG2 cells. It is utilized in the study of diseases associated with trypanosome infection [1].
价 格:¥电议型 号:T81503产 地:中国大陆
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T81471Phytoene desaturase-IN-2;化合物 Phytoene desaturase-IN-2Phytoene desaturase-IN-2
"PDS-IN-1 potently inhibits Oryza sativa phytoene desaturase (OsPDS), exhibiting herbicidal activity [1]."
价 格:¥电议型 号:T81471产 地:中国大陆
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T81465PI5P4K-β-IN-1;化合物 PI5P4K-β-IN-1PI5P4K-β-IN-1
PI5P4K-β-IN-1 (compound vs1) is a potent PI5P4K-β inhibitor with an IC50 of 0.80 μM [1].
价 格:¥电议型 号:T81465产 地:中国大陆
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T81464PI5P4K-β-IN-2;化合物 PI5P4K-β-IN-2PI5P4K-β-IN-2
PI5P4K-β-IN-2 (compound d5) is a potent inhibitor of the PI5P4K-β enzyme, demonstrating an IC50 value of 0.35 μM and exhibiting antitumor activity.
价 格:¥电议型 号:T81464产 地:中国大陆
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T81460PIM-IN-2;化合物 PIM-IN-2PIM-IN-2
PIM-IN-2 (Pim-2) is a potent inhibitor of Pim kinases, demonstrating an inhibition concentration half-maximal (IC50) value of 25 nM . It exhibits antiapoptotic properties conducive to cell survival and has been found to have increased expression levels across various human tumors [1].
价 格:¥电议型 号:T81460产 地:中国大陆
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T81443Plecstatin-1;化合物 Plecstatin-1Plecstatin-1
Plecstatin-1, an organoruthenium compound, serves as a potent anti-cancer agent that selectively targets plectin—a scaffold protein and cytolinker—within tumor spheroids.
价 格:¥电议型 号:T81443产 地:中国大陆
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T81441PLK1/p38γ-IN-1;化合物 PLK1/p38γ-IN-1PLK1/p38γ-IN-1
PLK1/p38γ-IN-1 (compound 14) serves as a dual inhibitor targeting both PLK1 and p38γ kinases, effectively suppressing the proliferation of human hepatocellular carcinoma and hepatoblastoma cell lines in vitro [1].
价 格:¥电议型 号:T81441产 地:中国大陆
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T81432PNMT-IN-1;化合物 PNMT-IN-1PNMT-IN-1
PNMT-IN-1 (inhibitor 4) is a selective second generation inhibitor [1] of phenylethanolamine N-methyltransferase (PNMT), exhibiting a Ki value of 1.2 nM and an IC50 value of 81 nM. Additionally, it disrupts the activity of DNMT1 and DNMT3b, with IC50 values of 61 μM and 17 μM, respectively, and antagonizes the action of epinephrine.
价 格:¥电议型 号:T81432产 地:中国大陆
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T81417PP5-IN-1;PP5抑制剂1PP5-IN-1
PP5-IN-1 is a potent and competitive serine/threonine protein phosphatase-5 (PP5) inhibitor with potential anticancer activity that induces apoptosis in cancer cells.
价 格:¥电议型 号:T81417产 地:中国大陆
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T81416PPO-IN-2;化合物 PPO-IN-2PPO-IN-2
PPO-IN-2 is a protoporphyrinogen IX oxidase inhibitor, exhibiting a Ki value of 16 nM [1].
价 格:¥电议型 号:T81416产 地:中国大陆
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T81399PRMT4-IN-2;化合物 PRMT4-IN-2PRMT4-IN-2
PRMT4-IN-2 (compound 55) acts as a pan-inhibitor across various protein arginine methyltransferase (PRMT) isoforms, exhibiting inhibitory potencies with IC50 values of 92 nM for PRMT4, 436 nM for PRMT6, 460 nM for PRMT1, 823 nM for PRMT8, and 1.386 μM for PRMT3 [1].
价 格:¥电议型 号:T81399产 地:中国大陆
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T81373Proteasome β2c/i-IN-1;化合物 Proteasome β2c/i-IN-1Proteasome β2c/i-IN-1
Proteasome β2c/i-IN-1 (compound 37) serves as a selective inhibitor targeting the β2c and β2i subunits of the human proteasome [1].
价 格:¥电议型 号:T81373产 地:中国大陆
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T81370Protegrin-1;化合物 Protegrin-1PG1;PG1
Protegrin-1, an antimicrobial peptide, exhibits antimicrobial activity [1].
价 格:¥电议型 号:T81370产 地:中国大陆
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T81343PYCR1-IN-1;化合物 PYCR1-IN-1PYCR1-IN-1
PYCR1-IN-1 (compound 4) is an inhibitor of pyrroline-5-carboxylate reductase 1 (PYCR1), exhibiting an IC50 value of 8.8 ?M, and possesses anticancer properties [1].
价 格:¥电议型 号:T81343产 地:中国大陆