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产品数:86101
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T1829(R)-Ruxolitinib(R)-Ruxolitinib,Ruxolitinib,INCB018424
Ruxolitinib is a potent and selective JAK1/2 inhibitor (IC50: 3.3/2.8 nM) and is relatively less selective for JAK3 (IC50: 322 nM).
价 格:¥电议型 号:T1829产 地:美洲
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T1940BTB06584BTB06584
BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against Mycobacterium tuberculosis (MTB).
价 格:¥电议型 号:T1940产 地:美洲
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T2260GW 9662GW 9662,TIMTEC-BB SBB006523,
GW9662 is a specific PPARγ antagonist (IC50: 3.3 nM, in a cell-free assay), with 100 to 1000-fold functional selectivity for PPARγ than PPARα/δ in cells.
价 格:¥电议型 号:T2260产 地:美洲
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T2286BIIB-021BIIB-021,BIIB021,BIIB 021
BIIB021 is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7nM,EC50=38nM).
价 格:¥电议型 号:T2286产 地:美洲
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T2330RilpivirineRilpivirine,DB08864,TMC278
Rilpivirine is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatment of HIV infections.
价 格:¥电议型 号:T2330产 地:美洲
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T2485BaricitinibBaricitinib,LY3009104,INCB028050
Baricitinib is an orally bioavailable inhibitor of Janus kinases 1 and 2 (JAK1/2), with potential anti-inflammatory, immunomodulating and antineoplastic activities.
价 格:¥电议型 号:T2485产 地:美洲
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T2647INCB024360 analogueINCB024360 analogue,IDO5L,INCB14943
IDO-IN-2 is an effective IDO1 inhibitor(IC50=10 nM).
价 格:¥电议型 号:T2647产 地:美洲
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T2696PRT062607 hydrochloridePRT062607 hydrochloride,P505-15 Hydrochloride,PRT062607 (P505-15, BIIB057) HC
PRT062607 (BIIB-057) is a selective inhibitor of Syk (IC50: 1 nM). It displays at least 80-fold selectivity for Syk over other kinases.
价 格:¥电议型 号:T2696产 地:美洲
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T4656B02B02,RAD51 Inhibitor B02,
RAD51 Inhibitor B02 (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 μM.
价 格:¥电议型 号:T4656产 地:美洲
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T5103AKOS B018304AKOS B018304
AKOS B018304 is an arylalkylidene derivative, with polar substitution at para-position.
价 格:¥电议型 号:T5103产 地:美洲
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T5417INCB057643INCB057643
INCB057643 is a potent, selective and orally bioavailable BET inhibitor.
价 格:¥电议型 号:T5417产 地:美洲
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T5804Pneumocandin B0Pneumocandin B0,L-688786,
Pneumocandin B0 is a natural product and a key intermediate in the synthesis of the antifungal agent.
价 格:¥电议型 号:T5804产 地:美洲
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T6278SotrastaurinSotrastaurin,AEB071,
Sotrastaurin is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).
价 格:¥电议型 号:T6278产 地:美洲
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T8608LFanetizole mesylate;化合物 T8608LUNII-D3OG7B0G4M|||CP 48810|||Fanetizole mesylate (USAN)|||C1MHW3X;UNII
Fanetizole mesylate is an immunoregulator agent.
价 格:¥电议型 号:T8608L产 地:中国大陆
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T81539PAT1inh-B01;化合物 PAT1inh-B01PAT1inh-B01
PAT1inh-B01, a selective SLC26A6 inhibitor, impedes PAT1 (a Cl-/HCO3- exchanger) activity, with an IC50 of 350 nM, effectively inhibiting anion exchange. It also obstructs fluid absorption in the small intestine and is utilized in the study of small intestinal hyposecretory disorders [1].
价 格:¥电议型 号:T81539产 地:中国大陆
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T81536PB089;化合物 PB089PB089
PB089 is a drug-like molecule featuring a polyethylene glycol (PEG) unit and a cleavable linker connected to Exatecan [1].
价 格:¥电议型 号:T81536产 地:中国大陆
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T80779WDB002;化合物 WDB002WDB002
WDB002, a natural product belonging to the FK506/rapamycin family, targets CEP250 and may be employed in COVID-19 research [1].
价 格:¥电议型 号:T80779产 地:中国大陆
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T80619Rosnilimab;化合物 RosnilimabANB030;ANB030
Rosnilimab is a humanized IgG1-κ antibody that targets PD-1 [1] [2].
价 格:¥电议型 号:T80619产 地:中国大陆
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T80589Zamerovimab;化合物 ZamerovimabSYN023|||CTB011;SYN023|||CTB011
Zamerovimab (CTB011; SYN023), a composite of human monoclonal antibodies CTB011 and CTB012, targets distinct, non-overlapping epitopes on the rabies virus (RABV) glycoprotein, with CTB011 specifically binding to antigenic site III. This compound is applicable in rabies research [1].
价 格:¥电议型 号:T80589产 地:中国大陆
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T80588Bintrafusp alfa;化合物 Bintrafusp alfaM7824|||MSB0011359C;M7824|||MSB0011359C
Bintrafusp alfa (M 7824), a pioneering bifunctional fusion protein, integrates the extracellular domain of TGF-βRII with a human IgG1 monoclonal antibody that inhibits the programmed cell death ligand. This compound is utilized in cancer research [1].
价 格:¥电议型 号:T80588产 地:中国大陆