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  • T67952JB062；化合物JB062JB062

    JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively. It selectively exhibits cytotoxicity towards human cancer cells without affecting normal cells. The compound is applicable in research fields concerning muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.

    价 格：￥电议型 号：T67952产 地：中国大陆

  • T67951JB061；化合物JB061JB061

    JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 μM (Cardiac muscle myosin), 9.1 μM (Skeletal muscle myosin), and >100 μM (Smooth muscle myosin II). It exhibits limited efficacy in reducing ATPase activity, with an IC50 exceeding 200 μM. Furthermore, JB061 displays cytotoxic effects on COS-7 cells, evidenced by an IC50 value of 39 μM.

    价 格：￥电议型 号：T67951产 地：中国大陆

  • T67892BTB09089；化合物BTB09089GPR65 agonist (BTB09089)；GPR65 agonist (BTB09089)

    BTB09089 (GPR65 agonist ) is a T cell death-associated gene 8 (TDAG8/GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine production in T cells and macrophages.

    价 格：￥电议型 号：T67892产 地：中国大陆

  • T67769MPT0B014；化合物MPT0B014MPT0B014

    MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis.

    价 格：￥电议型 号：T67769产 地：中国大陆

  • T63940B026；化合物 B026B026

    B026 is a selective, orally active inhibitor of p300/CBP histone acetyltransferase (p300/CBP HAT) that acts on p300 (IC50: 1.8 nM) and CBP (IC50: 9.5 nM). b026 exhibits anticancer effects on androgen receptor positive (AR+) prostate cancer cells.

    价 格：￥电议型 号：T63940产 地：中国大陆

  • T6278Sotrastaurin；索曲妥林AEB071；索曲妥林|||AEB071

    Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).

    价 格：￥电议型 号：T6278产 地：中国大陆

  • T62304Minzasolmin；化合物Minzasolmin(R)-NPT200-11|||UCB0599|||DLX-313；(R)-NPT200-11|||UCB0599|||DLX-313

    Minzasolmin(DLX-313) is an alpha-synuclein misfolding inhibitor for the study of Parkinson´s disease.

    价 格：￥电议型 号：T62304产 地：中国大陆

  • T61942SKLB0565；化合物 SKLB0565SKLB0565

    SKLB0565 is an effective inhibitor of tubulin. SKLB0565 significantly inhibited the proliferation of colorectal cancer cells with IC50 of 0.012 - 0.081 μ M。 SKLB0565 induces G2/M phase arrest and mitochondria-mediated endogenous apoptosis. SKLB0565 destroys the microtubule formation of HUVECs cells and inhibits cell migration.

    价 格：￥电议型 号：T61942产 地：中国大陆

  • T6156Ruxolitinib (S enantiomer)；环丙基[4-[3-(1H-咪唑-5-基)丙氧基]苯S-Ruxolitinib|||Ruxolitinib S enantiomer|||INCB0

    Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.

    价 格：￥电议型 号：T6156产 地：中国大陆

  • T5804Pneumocandin B0；纽莫康定B0L-688786；纽莫康定B0|||L-688786

    Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.

    价 格：￥电议型 号：T5804产 地：中国大陆

  • T5417INCB-057643；化合物INCB057643INCB-057643

    INCB057643 is a potent, selective and orally bioavailable BET inhibitor.

    价 格：￥电议型 号：T5417产 地：中国大陆

  • T5103AKOS B018304化合物AKOS B018304(5E)-5-(2-硝基苯亚甲基)-2-硫代-四氢噻唑-4-酮

    AKOS B018304 is an arylalkylidene derivative with polar substitution at para-position.

    价 格：￥电议型 号：T5103产 地：中国大陆

  • T4656RAD51 Inhibitor B02；化合物B02B02；B02

    RAD51 Inhibitor B02 (B02) (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 μM.

    价 格：￥电议型 号：T4656产 地：中国大陆

  • T4165Delpazolid；化合物DelpazolidLCB01-0371；LCB01-0371

    Delpazolid (LCB01-0371), also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacter

    价 格：￥电议型 号：T4165产 地：中国大陆

  • T40901Aderbasib；AderbasibINCB007839|||INCB7839；INCB007839|||INCB7839

    Aderbasib (INCB007839) is a highly potent and orally active hydroxamate-based inhibitor of ADAM10 and ADAM17, with low nanomolar affinity. This compound demonstrates strong antineoplastic activity and holds potential for cancer research in various areas, such as diffuse large B-cell non-Hodgkin lymphoma, HER2-positive breast cancer, gliomas, and more.

    价 格：￥电议型 号：T40901产 地：中国大陆

  • T4011NCB-0846；化合物NCB0846NCB 0846；NCB 0846

    NCB-0846 is an orally active TNIK inhibitor (IC50: 21 nM).

    价 格：￥电议型 号：T4011产 地：中国大陆

  • T3998Itacitinib；伊他替尼INCB39110|||INCB039110；伊他替尼|||INCB39110|||INCB039110

    Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.

    价 格：￥电议型 号：T3998产 地：中国大陆

  • T39945SYY-B085-1SYY-B085-1SYY-B085-1

    SYY-B085-1 is a histone acetyltransferase (HAT) inhibitor.

    价 格：￥电议型 号：T39945产 地：中国大陆

  • T39923KB02-COOHKB02-COOHKB02-COOH

    KB02-COOH is a synthetic fragment derived from ubiquitin E3 ligase ligand KB02, which possesses potential utility in the synthesis of PROTAC compounds. Notably, KB02-COOH can be employed in the generation of PROTAC constructs like KB02-JQ1 and KB02-SLF.

    价 格：￥电议型 号：T39923产 地：中国大陆

  • T39761BIIB091；BIIB091BIIB091

    BIIB091 is a highly selective, reversible BTK inhibitor for treating autoimmune diseases.

    价 格：￥电议型 号：T39761产 地：中国大陆

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