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T39650Tadnersen；TadnersenIONIS-C9Rx|||BIIB078；IONIS-C9Rx|||BIIB078
Tadnersen (BIIB078) is an antisense oligonucleotide (ASO) designed for the selective targeting of C9ORF72 transcript variants 1 and 3, specifically those carrying the expansion.
价 格：￥电议型 号：T39650产 地：中国大陆
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T39498Tofersen；TofersenBIIB067|||ISIS-SOD1Rx；BIIB067|||ISIS-SOD1Rx
Tofersen (BIIB067) is an antisense oligonucleotide utilized to inhibit the synthesis of superoxide dismutase 1 (SOD1) protein by facilitating the degradation of SOD1 mRNA via the RNase H-dependent mechanism. This compound holds potential for amyotrophic lateral sclerosis (ALS) research.
价 格：￥电议型 号：T39498产 地：中国大陆
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T39226INCB059872INCB059872INCB059872
INCB059872 is a highly potent, orally active, selective, and irreversible inhibitor of Lysine-Specific Demethylase 1 (LSD1). Its chemical properties make it suitable for use in researching myeloid leukemia.
价 格：￥电议型 号：T39226产 地：中国大陆
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T39090Uzansertib；UzansertibINCB053914；INCB053914
Uzansertib (INCB053914) is a potent ATP-competitive pan-PIM kinase inhibitor. It exhibits exceptional inhibitory activity against PIM1, PIM2, and PIM3 with IC50 values of 0.24 nM, 30 nM, and 0.12 nM, respectively. Furthermore, Uzansertib demonstrates significant anti-proliferative effects against an assorted range of hematologic tumor cell lines.
价 格：￥电议型 号：T39090产 地：中国大陆
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T37646HB007；HB007HB007
HB007 is a potent degrader of small ubiquitin-related modifier 1 (SUMO1). It mediates the ubiquitination and subsequent degradation of SUMO1, leading to a decrease in tumor growth in vivo. HB007 is a valuable tool for investigating brain, breast, colon, and lung cancers[1][2].
价 格：￥电议型 号：T37646产 地：中国大陆
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T36899INCB086550；化合物INCB086550PD-1/PD-L1-IN-8；PD-1/PD-L1-IN-8
INCB086550 (PD-1/PD-L1-IN-8) (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.
价 格：￥电议型 号：T36899产 地：中国大陆
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T32151INCB052793；化合物 T32151INCB 052793|||INCB-052793；INCB 052793|||INCB-052793
INCB052793 is an oral Janus-associated kinase 1 (JAK1) inhibitor with potential anti-tumor activity.
价 格：￥电议型 号：T32151产 地：中国大陆
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T3200DB07268；化合物DB07268DB07268
DB07268 is a potent and selective JNK1 inhibitor.
价 格：￥电议型 号：T3200产 地：中国大陆
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T30847CGP-42454A；化合物 T30847CGP42454A|||UNII-15B0UK1949；CGP42454A|||UNII-15B0UK1949
CGP-42454A is a bio-active chemical.
价 格：￥电议型 号：T30847产 地：中国大陆
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T3043Ruxolitinib phosphate；磷酸鲁索利替尼INC424|||INCB018424|||INC 424 phosphate|||Ruxolitinib (INCB-18424) phos
Ruxolitinib phosphate (INCB018424)(INCB018424 phosphate) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3.
价 格：￥电议型 号：T3043产 地：中国大陆
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T30092AP-24226；化合物 T3009253D46B0TIH|||UNII-53D46B0TIH|||CHEMBL556874；53D46B0TIH|||UNII-53D46B0TIH|||CHEMBL
AP-24226 is a potent dual Src/ ABL kinase inhibitor.
价 格：￥电议型 号：T30092产 地：中国大陆
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T29704AG-1812 free base；化合物 T29704UNII-6RI44GB0V9|||HE078804|||AC1MIZB6|||Lansoprazole disulfide active me
ABT-1812 is a bio-active chemical.
价 格：￥电议型 号：T29704产 地：中国大陆
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T2948Ethylvanillin acetate；乙酰乙基香兰酯4-Acetoxy-3-ethoxybenzaldehyde|||AKOS B004453|||Ethyl vanillin acetate；
Ethyl vanillin acetate, the ethyl acetate form of ethyl vanillin, is utilized as a flavoring agent in chocolate or confectionery.
价 格：￥电议型 号：T2948产 地：中国大陆
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T28504RB-042 HCl；化合物 T28504RB 042|||RB042|||RB-042 hydrochloride|||RB-042；RB 042|||RB042|||RB-042 hydrochl
RB-042 is SphK inhibitor.
价 格：￥电议型 号：T28504产 地：中国大陆
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T28039Milfasartan；化合物 T28039LR-B081|||LRB-081|||LR-B-081|||LRB 081|||LR-B 081；LR-B081|||LRB-081|||LR-B-081
Milfasartan is a potent, selective antagonist of AT1 receptor with oral activity. It markedly lowers the blood-pressure in conscious renal and spontaneously hypertensive rats.
价 格：￥电议型 号：T28039产 地：中国大陆
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T27739KR-31378；化合物 T27739MSH1001|||DNB 001|||DNB-001|||DNB001|||MSH-1001|||KR31378；MSH1001|||DNB 001|||DNB
KR-31378, a K(ATP) channel activator, is used potentially for the treatment of ocular hypertension and glaucoma.
价 格：￥电议型 号：T27739产 地：中国大陆
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T27604INCB-9471 HCl；化合物 T27604INCB 9471|||INCB-9471|||INCB9471|||INCB-009471|||INCB 009471|||INCB009471；IN
INCB-9471 HCl, an allosteric noncompetitive small-molecule antagonist of C-C chemokine receptor 5, has potent inhibitory activity against monocyte migration and HIV-1 infection.
价 格：￥电议型 号：T27604产 地：中国大陆
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T27591II-B08；化合物 T27591II-B 08|||FAP1 Inhibitor|||II-B-08|||LMWPTP Inhibitor|||Lyp Inhibitor III|||CD45 In
II-B08 is a cell-permeable SHP2 inhibitor (IC50 = 5.5 ?M). II-B08 blocks growth factor stimulated ERK1/2 activation and hematopoietic progenitor proliferation.
价 格：￥电议型 号：T27591产 地：中国大陆
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T27157Dezapelisib；化合物 T27157INCB-040093|||INCB 040093|||INCB040093；INCB-040093|||INCB 040093|||INCB040093
Dezapelisib is an orally bioavailable, selective inhibitor of the delta isoform of the 110 kDa catalytic subunit of class I phosphoinositide-3 kinases (PI3K). INCB040093 prevents both the production of the second messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and the activation of the PI3K/AKT kinase signaling pathway. This decreases proliferation and induces cell death in PI3K-overexpressing tumor cells.
价 格：￥电议型 号：T27157产 地：中国大陆
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T27005Chinfloxacin；化合物 T27005IMB-031124|||IMB 031124|||IMB031124；IMB-031124|||IMB 031124|||IMB031124
Chinfloxacin, a quinolone antibiotic, is used potentially for the treatment of bacterial infections.
价 格：￥电议型 号：T27005产 地：中国大陆
