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  • T16110ML418ML418

    ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.

    价 格:¥电议型 号:T16110产 地:美洲

  • T16113ML753286ML753286

    ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions. ML753286 is an orally active and selective inhibitor of BCRP (IC50: 0.6 μM). It is also stable in plasma across species.

    价 格:¥电议型 号:T16113产 地:美洲

  • T16114PavinetantPavinetant,MLE-4901,AZD2624

    Pavinetant is an antagonist of the neurokinin-3 receptor (NK3R).

    价 格:¥电议型 号:T16114产 地:美洲

  • T16115MLi-2MLi-2

    MLi-2 has the potential for Parkinson’s disease. MLi-2 is an orally active and highly selective LRRK2 inhibitor (IC50: 0.76 nM).

    价 格:¥电议型 号:T16115产 地:美洲

  • T16116MLN-4760MLN-4760

    MLN-4760 is an effective and selective inhibitor of human ACE2 (IC50, 0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM).

    价 格:¥电议型 号:T16116产 地:美洲

  • T16117Pevonedistat hydrochloridePevonedistat hydrochloride,MLN4924 hydrochloride,

    Pevonedistat hydrochloride is an effective and selective inhibitor of NEDD8-activating enzyme (IC50: 4.7 nM).

    价 格:¥电议型 号:T16117产 地:美洲

  • T16118MLS0315771MLS0315771

    MLS0315771 is an effective and biologically active competitive phosphomannose isomerase (MPI) inhibitor (IC50: ~1 μM and a Ki: 1.4 μM).

    价 格:¥电议型 号:T16118产 地:美洲

  • T19611(2R)-Octyl-α-hydroxyglutarate(2R)-Octyl-α-hydroxyglutarate,(2R)-Octyl-2-HG,

    (2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a D-isomer 2-Hydroxyglutarate modified form.

    价 格:¥电议型 号:T19611产 地:美洲

  • T2020RGW 611RGW 611

    Detail unknown.

    价 格:¥电议型 号:T2020产 地:美洲

  • T2216EntacaponeEntacapone,OR-611,

    Entacapone is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).

    价 格:¥电议型 号:T2216产 地:美洲

  • T6110YM201636YM201636

    YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue.

    价 格:¥电议型 号:T6110产 地:美洲

  • T6111SelisistatSelisistat,EX-527,SEN0014196

    EX 527 is an effective and specific SIRT1 inhibitor (IC50: 38 nM) and shows >200-fold selectivity against SIRT2/3.

    价 格:¥电议型 号:T6111产 地:美洲

  • T6112DoxercalciferolDoxercalciferol,1.alpha.-Hydroxyvitamin D2,1α-hydroxyvitamin D2

    Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.

    价 格:¥电议型 号:T6112产 地:美洲

  • T6114NifursolNifursol

    Nifursol is a livestock feed additive and antiobiotic used to prevent the growth of histomonas.

    价 格:¥电议型 号:T6114产 地:美洲

  • T6115FostamatinibFostamatinib,R788,

    Fostamatinib(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.

    价 格:¥电议型 号:T6115产 地:美洲

  • T6116Bleomycin SulfateBleomycin Sulfate,NSC125066,Blenoxane

    Bleomycin Sulfate, a glycopeptide antibiotic, is an anticancer agent for squamous cell carcinomas (SCC). In UT-SCC-19A cells, the IC50 of Bleomycin Sulfate is 4 nM.

    价 格:¥电议型 号:T6116产 地:美洲

  • T6117TivantinibTivantinib,ARQ 197,

    Tivantinib is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity.

    价 格:¥电议型 号:T6117产 地:美洲

  • T6118HSP990HSP990,NVP-HSP990,

    NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).

    价 格:¥电议型 号:T6118产 地:美洲

  • T6119BLZ945BLZ945

    BLZ945 is an orally active, effective and specific CSF-1R inhibitor (IC50: 1 nM), >1000-fold selective against its closest receptor tyrosine kinase homologs.

    价 格:¥电议型 号:T6119产 地:美洲

  • T6121TepotinibTepotinib,EMD-1214063,MSC2156119

    Tepotinib is an inhibitor of MET tyrosine kinase with potential antineoplastic activity.

    价 格:¥电议型 号:T6121产 地:美洲

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