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T16110ML418ML418
ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.
价 格:¥电议型 号:T16110产 地:美洲
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T16113ML753286ML753286
ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions. ML753286 is an orally active and selective inhibitor of BCRP (IC50: 0.6 μM). It is also stable in plasma across species.
价 格:¥电议型 号:T16113产 地:美洲
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T16114PavinetantPavinetant,MLE-4901,AZD2624
Pavinetant is an antagonist of the neurokinin-3 receptor (NK3R).
价 格:¥电议型 号:T16114产 地:美洲
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T16115MLi-2MLi-2
MLi-2 has the potential for Parkinson’s disease. MLi-2 is an orally active and highly selective LRRK2 inhibitor (IC50: 0.76 nM).
价 格:¥电议型 号:T16115产 地:美洲
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T16116MLN-4760MLN-4760
MLN-4760 is an effective and selective inhibitor of human ACE2 (IC50, 0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM).
价 格:¥电议型 号:T16116产 地:美洲
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T16117Pevonedistat hydrochloridePevonedistat hydrochloride,MLN4924 hydrochloride,
Pevonedistat hydrochloride is an effective and selective inhibitor of NEDD8-activating enzyme (IC50: 4.7 nM).
价 格:¥电议型 号:T16117产 地:美洲
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T16118MLS0315771MLS0315771
MLS0315771 is an effective and biologically active competitive phosphomannose isomerase (MPI) inhibitor (IC50: ~1 μM and a Ki: 1.4 μM).
价 格:¥电议型 号:T16118产 地:美洲
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T19611(2R)-Octyl-α-hydroxyglutarate(2R)-Octyl-α-hydroxyglutarate,(2R)-Octyl-2-HG,
(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a D-isomer 2-Hydroxyglutarate modified form.
价 格:¥电议型 号:T19611产 地:美洲
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T2216EntacaponeEntacapone,OR-611,
Entacapone is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).
价 格:¥电议型 号:T2216产 地:美洲
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T6110YM201636YM201636
YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue.
价 格:¥电议型 号:T6110产 地:美洲
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T6111SelisistatSelisistat,EX-527,SEN0014196
EX 527 is an effective and specific SIRT1 inhibitor (IC50: 38 nM) and shows >200-fold selectivity against SIRT2/3.
价 格:¥电议型 号:T6111产 地:美洲
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T6112DoxercalciferolDoxercalciferol,1.alpha.-Hydroxyvitamin D2,1α-hydroxyvitamin D2
Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.
价 格:¥电议型 号:T6112产 地:美洲
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T6114NifursolNifursol
Nifursol is a livestock feed additive and antiobiotic used to prevent the growth of histomonas.
价 格:¥电议型 号:T6114产 地:美洲
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T6115FostamatinibFostamatinib,R788,
Fostamatinib(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.
价 格:¥电议型 号:T6115产 地:美洲
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T6116Bleomycin SulfateBleomycin Sulfate,NSC125066,Blenoxane
Bleomycin Sulfate, a glycopeptide antibiotic, is an anticancer agent for squamous cell carcinomas (SCC). In UT-SCC-19A cells, the IC50 of Bleomycin Sulfate is 4 nM.
价 格:¥电议型 号:T6116产 地:美洲
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T6117TivantinibTivantinib,ARQ 197,
Tivantinib is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity.
价 格:¥电议型 号:T6117产 地:美洲
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T6118HSP990HSP990,NVP-HSP990,
NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).
价 格:¥电议型 号:T6118产 地:美洲
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T6119BLZ945BLZ945
BLZ945 is an orally active, effective and specific CSF-1R inhibitor (IC50: 1 nM), >1000-fold selective against its closest receptor tyrosine kinase homologs.
价 格:¥电议型 号:T6119产 地:美洲
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T6121TepotinibTepotinib,EMD-1214063,MSC2156119
Tepotinib is an inhibitor of MET tyrosine kinase with potential antineoplastic activity.
价 格:¥电议型 号:T6121产 地:美洲