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T61177NSC114126；化合物 NSC114126NSC114126
NSC114126 is a highly effective and orally bioavailable inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR-TK). This compound exhibits robust antiproliferative properties, making it a promising candidate for further investigation in the field of cancer research [1].
价 格：￥电议型 号：T61177产 地：中国大陆
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T61176MRK-623；化合物 MRK-623MRK-623
MRK-623 (Compound 14k) is a potent, orally active agonist of the GABA A receptor, exhibiting high affinity for subunits α1, α2, α3, and α5 with Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM, respectively. Notably, MRK-623 demonstrates anxiolytic effects [1].
价 格：￥电议型 号：T61176产 地：中国大陆
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T611754-((4-((4-Aminophenyl)sulfonyl)phenyl)amino)-4-oxobutanoic acid；化合物 4-((4-((4-Aminophenyl)sulfonyl)p
4-((4-((4-Aminophenyl)sulfonyl)phenyl)amino)-4-oxobutanoic acid is a sulfonamide compound that can be used as an anti infective agent [1].
价 格：￥电议型 号：T61175产 地：中国大陆
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T61174MT-134；化合物 MT-134MT-134
MT-134 is a SkMII -specific inhibitor and has excellent exposure in muscles.
价 格：￥电议型 号：T61174产 地：中国大陆
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T61173Metallo-β-lactamase-IN-5；化合物 Metallo-β-lactamase-IN-5Metallo-β-lactamase-IN-5
Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs). Its inhibitory activity against MBLs NDM-1 and VIM-1 has been demonstrated. With an IC50 value of 45 μg/mL, Metallo-β-lactamase-IN-5 effectively inhibits HUVECs. Additionally, when combined with Imipenem, Metallo-β-lactamase-IN-5 exhibits synergistic antimicrobial activity [1].
价 格：￥电议型 号：T61173产 地：中国大陆
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T61172NRX-1532；化合物NRX-1532NRX1532|||NRX 1532；NRX1532|||NRX 1532
NRX-1532 is a small molecule β-catenin:β-TrCP interaction enhancer.
价 格：￥电议型 号：T61172产 地：中国大陆
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T61170Antibacterial agent 96；化合物 Antibacterial agent 96Antibacterial agent 96
Antibacterial Agent 96 (Compound 4k) is a potent antibacterial and antitubercular compound effective against both drug-susceptible and multidrug-resistant Mycobacterium tuberculosis (M. tuberculosis) strains. However, it exhibits toxicity to HepG2 and Vero cells [1].
价 格：￥电议型 号：T61170产 地：中国大陆
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T6117Tivantinib；化合物TivantinibARQ 197；ARQ 197
Tivantinib (ARQ 197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity.
价 格：￥电议型 号：T6117产 地：中国大陆
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T6116LBleomycin hydrochloride；盐酸博来霉素Bleomycin hydrochloride
Bleomycin hydrochloride is a potent antitumor antibiotic that functions as a DNA synthesis inhibitor and DNA damaging agent.
价 格：￥电议型 号：T6116L产 地：中国大陆
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T61169PqsR-IN-1；化合物 PqsR-IN-1PqsR-IN-1
PqsR-IN-1 (Compound 18) is a potent inhibitor of PqsR, which is a transcriptional regulator involved in the quorum sensing mechanism of Pseudomonas aeruginosa. This compound effectively reduces the production of pyocyanin and exhibits minimal cytotoxicity [1].
价 格：￥电议型 号：T61169产 地：中国大陆
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T61168CAY10590；化合物 CAY10590CAY10590
CAY10590 (GK115) is a compound that functions as an inhibitor of secreted phospholipase A2 (sPLA2). It is commonly employed in research related to chronic inflammatory kidney diseases [1].
价 格：￥电议型 号：T61168产 地：中国大陆
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T61167PptT-IN-1；化合物 PptT-IN-1PptT-IN-1
PptT-IN-1 (compound 5j) is a highly potent inhibitor (IC50: 2.8 μM) of phosphopantetheinyl phosphoryl transferase (PptT), a crucial enzyme involved in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. This compound shows considerable potential for tuberculosis research [1].
价 格：￥电议型 号：T61167产 地：中国大陆
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T61166α-Glucosidase-IN-16；化合物 α-Glucosidase-IN-16α-Glucosidase-IN-16
α-Glucosidase-IN-16 is a highly effective and orally bioavailable inhibitor of α-glucosidase, displaying a remarkable IC50 value of 3.28 μM. This compound demonstrates the ability to significantly decrease blood glucose levels in diabetic rats induced by Streptozotocin. Notably, α-Glucosidase-IN-16 also exhibits noteworthy antidiabetic activity [1].
价 格：￥电议型 号：T61166产 地：中国大陆
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T61164hCAII-IN-3；化合物 hCAII-IN-3hCAII-IN-3
hCAII-IN-3 (Compound 16) is an inhibitor of human carbonic anhydrase (hCA). It exhibits high affinity for hCA I, hCA II, hCA IX, and hCA XII, with Ki values of 403.8 nM, 5.1 nM, 10.2 nM, and 5.2 nM, respectively. Notably, hCA IX-IN-2 demonstrates anticancer activity [1].
价 格：￥电议型 号：T61164产 地：中国大陆
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T61163Protein kinase D inhibitor 1；化合物 Protein kinase D inhibitor 1Protein kinase D inhibitor 1
Protein kinase D inhibitor 1 (compound 17m) is a potent pan-PKD inhibitor. It exhibits inhibitory activity in the low nanomolar range, with IC50 values ranging between 17 and 35 nM. By inhibiting protein kinase D, this compound effectively suppresses cortactin phosphorylation, which is known to be PKD-dependent [1].
价 格：￥电议型 号：T61163产 地：中国大陆
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T61162Xanthine oxidoreductase-IN-2；化合物 Xanthine oxidoreductase-IN-2Xanthine oxidoreductase-IN-2
Xanthine oxidoreductase-IN-2 (Compound IVa) is a potent inhibitor of xanthine oxidoreductase (XOR) with an IC50 value of 7.2 nM. Notably, Xanthine oxidoreductase-IN-2 demonstrates hypouricemic effects in mice, as evidenced by [1].
价 格：￥电议型 号：T61162产 地：中国大陆
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T61161HIF-1α-IN-3；化合物 HIF-1α-IN-3HIF-1α-IN-3
HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1].
价 格：￥电议型 号：T61161产 地：中国大陆
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T61160Antiparasitic agent-2；化合物 Antiparasitic agent-2Antiparasitic agent-2
Antiparasitic agent-2 (compound 8a) exhibits potent antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi), with IC50s of 7.28 μM and 2.30 μM, respectively. Additionally, it demonstrates moderate cytotoxicity against HepG2 cells with a CC50 of 26.79 μM [1].
价 格：￥电议型 号：T61160产 地：中国大陆
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T6116Bleomycin Sulfate；硫酸博来霉素Blenoxane|||NSC125066；Blenoxane|||硫酸博来霉素|||硫酸博莱霉素|||NSC125066
Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis. Bleomycin Sulfate causes DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has antitumor activity.
价 格：￥电议型 号：T6116产 地：中国大陆
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T61159Antibacterial agent 26；抗菌剂26Antibacterial agent 26
Antibacterial agent 26 is an antimicrobial compound that is a potent DHFR inhibitor (S. aureus DHFR Ki of 0.020 nM).
价 格：￥电议型 号：T61159产 地：中国大陆
