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T6112Doxercalciferol；度骨化醇TSA 840|||Hectorol|||1.alpha.-Hydroxyvitamin D2|||1α-hydroxyvitamin D2；TSA 840||
Doxercalciferol (TSA 840) is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.
价 格：￥电议型 号：T6112产 地：中国大陆
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T61119MtDTBS-IN-1；化合物 MtDTBS-IN-1MtDTBS-IN-1
MtDTBS-IN-1 is a notably potent binder (K_D = 57 nM) and inhibitor (K_i = 5 μM) of MtDTBS.
价 格：￥电议型 号：T61119产 地：中国大陆
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T61118CD73-IN-12；化合物 CD73-IN-12CD73-IN-12
CD73-IN-12 is a highly effective CD73 inhibitor that displays strong potential in tumor suppression. CD73, an enzyme intricately linked to tumor development, angiogenesis, and metastasis, is significantly inhibited by CD73-IN-12. This compound holds promise in the formulation of therapeutic medications targeting tumor-related diseases[1].
价 格：￥电议型 号：T61118产 地：中国大陆
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T61117NMDA receptor modulator 5；化合物 NMDA receptor modulator 5NMDA receptor modulator 5
NMDA receptor modulator 5 (Compound 195), a potent NMDA receptor modulator, exhibits potential for neurological disorder research [1].
价 格：￥电议型 号：T61117产 地：中国大陆
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T61116NSC405640；化合物 NSC405640NSC405640
NSC405640 is a highly effective compound that inhibits the interaction between MDM2 and p53 proteins. Furthermore, it can restore the structural integrity of p53 molecules affected by mutations. Notably, NSC405640 exhibits selectivity in inhibiting the growth of cell lines that possess the normal, unmutated form of the p53 protein [1].
价 格：￥电议型 号：T61116产 地：中国大陆
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T61115HBV-IN-25；化合物 HBV-IN-25HBV-IN-25
HBV-IN-25 is a novel chemical compound that acts as a potent HBV cccDNA reducer when administered orally. It exhibits significant anti-HBeAg potency and anti-HBV activity, with IC50 values of 0.58 μM and 1.15 μM, respectively. Moreover, HBV-IN-25 demonstrates favorable aqueous solubility (LYSA＞452 μg/mL) and no cellular toxicity, making it a promising candidate for further investigation and development [1].
价 格：￥电议型 号：T61115产 地：中国大陆
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T61114Anti-Trypanosoma cruzi agent-2；化合物 Anti-Trypanosoma cruzi agent-2Anti-Trypanosoma cruzi agent-2
Anti-Trypanosoma cruzi agent-1 (Compd 3b), selective compound against NINOA trypomastigote (IC 50 = 0.51 μM) and INC-5 epimastigote form (IC 50 = 3.06 μM), posseses anti- T. gondii activity [1].
价 格：￥电议型 号：T61114产 地：中国大陆
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T61112SLF1081851；化合物SLF1081851SLF1081851
SLF1081851 is a Spns2 inhibitor. SLF1081851 inhibits S1P release with IC50 of 1.93 μM.
价 格：￥电议型 号：T61112产 地：中国大陆
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T61111UCB-5307；化合物UCB-5307UCB-5307
UCB-5307 is a small molecule compound that inhibits TNFR1 signal transduction and downstream function in vitro. The KD of human TNFα is 9 nM. The TNF was directly bound by slow binding kinetics,KD= 6 nM. UCB-5307 can pass through prefabricated hTNF/hTNFR1 complexes.
价 格：￥电议型 号：T61111产 地：中国大陆
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T61110UC-1V150；化合物 UC-1V150UC-1V150
UC-1V150 is a distinct TLR7 agonist, which activates cellular immune responses and exhibits anti-tumor effects. It also serves as a precursor for the synthesis of ISAC molecules, known as immune-stimulating antibody conjugates [1] [2].
价 格：￥电议型 号：T61110产 地：中国大陆
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T6111Selisistat；司来司他EX-527|||SEN0014196；EX-527|||司来司他|||SEN0014196
Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM). Selisistat can be used in the study of neurological disorders such as Huntington´s chorea.
价 格：￥电议型 号：T6111产 地：中国大陆
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T61109HG122；化合物 HG122HG122
HG122 is a chemical compound that effectively facilitates the degradation of androgen receptor (AR) via the proteasome pathway, leading to the inhibition of castration-resistant prostate cancer.
价 格：￥电议型 号：T61109产 地：中国大陆
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T61108YXL-13；化合物 YXL-13YXL-13
YXL-13 is a highly effective inhibitor of Pseudomonas aeruginosa (PAO1), with an IC50 value of 3.686 μM. It effectively hinders the expression of virulence factors and inhibits biofilm formation in PAO1. Moreover, YXL-13 significantly diminishes both the pathogenicity and drug resistance of PAO1 by inhibiting the quorum sensing (QS) system. Thus, YXL-13 holds great potential for studying antibacterial properties [1].
价 格：￥电议型 号：T61108产 地：中国大陆
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T61107Tilomisole；噻氯咪索Wy 18251；Wy 18251
Tilomisole (Wy 18251) is an orally available benzimidazole thiazole with anti-inflammatory activity and immunomodulatory activity.Tilomisole is used in the study of cancer and inflammation.
价 格：￥电议型 号：T61107产 地：中国大陆
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T61106GRP78-IN-1；化合物 GRP78-IN-1GRP78-IN-1
GRP78-IN-1 displays interactions with specific residues on the GRP78 protein with a binding energy of -8.07 kcal/mol. This compound possesses potent cytotoxic and anti-proliferative effects on cancer cells, particularly demonstrating promising apoptosis in breast cancer cells and wound healing properties [1].
价 格：￥电议型 号：T61106产 地：中国大陆
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T61105GAT228；化合物 GAT228GAT228
GAT228, an allosteric ligand for the cannabinoid receptor 1 (CB1), functions as the enantiomer of GAT211 [1].
价 格：￥电议型 号：T61105产 地：中国大陆
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T61104Antibacterial agent 82；化合物 Antibacterial agent 82Antibacterial agent 82
Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].
价 格：￥电议型 号：T61104产 地：中国大陆
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T61103Glyoxalase I inhibitor 5；化合物 Glyoxalase I inhibitor 5Glyoxalase I inhibitor 5
Glyoxalase I inhibitor 5 (Compound 9h) is a potent inhibitor of glyoxalase I (Glo-I), with an IC50 value of 1.28 μM. This compound holds promise as an anticancer agent [1].
价 格：￥电议型 号：T61103产 地：中国大陆
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T61102HIF-1/2α-IN-2；化合物 HIF-1/2α-IN-2HIF-1/2α-IN-2
HIF-1/2α-IN-2 is a potent inhibitor of HIF-1/2α, which effectively reduces the levels of HIF-1/2α. This compound elicits an iron starvation response by specifically targeting ISCA2, a key protein involved in Iron Sulfur Cluster Assembly 2. [1]
价 格：￥电议型 号：T61102产 地：中国大陆
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T61101FLT3-IN-13；化合物 FLT3-IN-13FLT3-IN-13
FLT3-IN-13 (compound 20) is a highly effective inhibitor targeting both topoisomerase II and FLT3 proteins in leukemic cells. It exhibits potent activity against these targets, with IC50 values of 2.26 μM for both. Moreover, FLT3-IN-13 induces cell cycle arrest at the G2/M phase and promotes apoptosis. Notably, it displays considerable anticytotoxic activity, specifically against leukemia [1].
价 格：￥电议型 号：T61101产 地：中国大陆
