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T6114Nifursol硝呋索尔硝呋索尔|||尼呋索尔
Nifursol is a livestock feed additive and antiobiotic used to prevent the growth of histomonas.
价 格:¥电议型 号:T6114产 地:中国大陆
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T61139HDAC6-IN-3;化合物 HDAC6-IN-3HDAC6-IN-3
HDAC6-IN-3 (Compound 14) is a potent anti-prostate cancer agent that acts as an orally active inhibitor of HDAC6. It has IC50 values ranging from 0.02-1.54 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10. Additionally, HDAC6-IN-3 also demonstrates effective inhibition of MAO-A (IC50 = 0.79 μM) and LSD1 [1].
价 格:¥电议型 号:T61139产 地:中国大陆
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T61138Bevantolol;化合物 BevantololBevantolol
Bevantolol, a selective β-1 adrenoceptor antagonist, is utilized for the investigation of angina pectoris and hypertension [1].
价 格:¥电议型 号:T61138产 地:中国大陆
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T61137VEGFR-2-IN-19;化合物 VEGFR-2-IN-19VEGFR-2-IN-19
VEGFR-2-IN-19 (Compound 15b) is a highly efficacious inhibitor of VEGFR2, a receptor involved in angiogenesis. Its mechanism of action involves the induction of cellular apoptosis and elevation of intracellular reactive oxygen species. Due to these properties, VEGFR-2-IN-19 holds promise as an effective anticancer agent [1].
价 格:¥电议型 号:T61137产 地:中国大陆
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T61136Enpp-1-IN-11;化合物 Enpp-1-IN-11Enpp-1-IN-11
Enpp-1-IN-11 (compound 23) is a highly potent inhibitor of Ecto-nucleotide pyrophosphatase/phosphodiesterases 1 (ENPP1), with a Ki value of 45 nM. It demonstrates excellent stability in human and mouse plasma and exhibits low clearance in both human and mouse liver microsomes. Enpp-1-IN-11 holds promise for anticancer research [1].
价 格:¥电议型 号:T61136产 地:中国大陆
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T61135β-N-Acetyl-D-hexosaminidase-IN-1;化合物 β-N-Acetyl-D-hexosaminidase-IN-1β-N-Acetyl-D-hexosaminidase-IN-
β-N-Acetyl-D-hexosaminidase-IN-1 is a newly discovered chemical compound that acts as an inhibitor for β-N-acetyl-D-hexosaminidase. It exhibits a Ki value of 3.72 μM, indicating its potency in inhibiting the enzyme´s activity.
价 格:¥电议型 号:T61135产 地:中国大陆
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T61134HIV-1 inhibitor-36;化合物 HIV-1 inhibitor-36HIV-1 inhibitor-36
HIV-1 inhibitor-36 (Compound 2) is a potent HIV-1 inhibitor with significant potential as a novel latency reversing agent [1].
价 格:¥电议型 号:T61134产 地:中国大陆
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T61133SSAO/VAP-1 inhibitor 1;化合物 SSAO/VAP-1 inhibitor 1SSAO/VAP-1 inhibitor 1
SSAO/VAP-1 Inhibitor 1 is a potent compound aimed at inhibiting SSAO/VAP-1, a protein involved in facilitating the translocation of Glucose Transport 4 (GLUT 4) to the cell membrane in adipocytes, thus playing a crucial role in glucose regulation. Additionally, in endothelial cells, this enzyme is responsible for mediating the adherence and infiltration of leukocytes, contributing to inflammatory responses. Given these mechanisms, SSAO/VAP-1 Inhibitor 1 holds considerable potential for research
价 格:¥电议型 号:T61133产 地:中国大陆
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T61132NLRP3-IN-11;NLRP3抑制剂11NLRP3-IN-11
NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.
价 格:¥电议型 号:T61132产 地:中国大陆
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T61131MAO-B-IN-11;化合物 MAO-B-IN-11MAO-B-IN-11
MAO-B-IN-11, also known as Compound 8c, is a highly potent inhibitor of monoamine oxidase B (MAO-B), with an IC50 value of 1.3 μM. Additionally, MAO-B-IN-11 exhibits neuroprotective properties [1].
价 格:¥电议型 号:T61131产 地:中国大陆
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T61130SSTR4 agonist 3;化合物 SSTR4 agonist 3SSTR4 agonist 3
SSTR4 agonist 3 is a potent compound that activates the SSTR4 receptor. The SSTR4 receptor is highly expressed in the hippocampus and neocortex, which are regions associated with memory, learning, and Alzheimer´s disease pathology. SSTR4 agonists demonstrate strong efficacy in rodent models of pain, both acute and chronic, by reducing peripheral nociception and inflammation. Considering its potential application in pain research, SSTR4 agonist 3 is of interest[1].
价 格:¥电议型 号:T61130产 地:中国大陆
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T6113ICG-001;化合物ICG-001ICG-001
ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.
价 格:¥电议型 号:T6113产 地:中国大陆
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T61129Tubulin polymerization-IN-27;化合物 Tubulin polymerization-IN-27Tubulin polymerization-IN-27
Tubulin polymerization-IN-27 (compound 5j) is an inhibitor of tubulin polymerization. It has the ability to halt the cell cycle specifically at the G2/M phase and also induce apoptosis [1].
价 格:¥电议型 号:T61129产 地:中国大陆
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T61128c-ABL-IN-2;化合物 c-ABL-IN-2c-ABL-IN-2
C-ABL-IN-2 is a highly effective inhibitor of the c-Abl protein, which plays a significant role in the development of several diseases, including cancer. This compound exhibits promise for investigating neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) and Parkinson´s disease (PD), as well as cancer. (Source: WO2020260871A1, compound 25) [1].
价 格:¥电议型 号:T61128产 地:中国大陆
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T61126Antibacterial synergist 1;化合物 Antibacterial synergist 1Antibacterial synergist 1
Antibacterial synergist 1 (compound 20P) is a potent inhibitor of bacterial biofilm formation. It effectively suppresses the production of pyocyanin, with an IC 50 of 8.6 μM, and inhibits biofilm formation with an IC 50 of 4.5 μM. Antibacterial synergist 1 shows promise in the research of P. aeruginosa infections [1].
价 格:¥电议型 号:T61126产 地:中国大陆
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T61124α-Glucosidase-IN-9;化合物 α-Glucosidase-IN-9α-Glucosidase-IN-9
α-Glucosidase-IN-9 (compound 7) is a highly potent α-glucosidase inhibitor with an IC50 of 55.6 μM, making it suitable for type II diabetes research [1].
价 格:¥电议型 号:T61124产 地:中国大陆
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T61123Antibacterial agent 111;化合物 Antibacterial agent 111Antibacterial agent 111
Antibacterial agent 111 (Compound 3) exhibits potent antibacterial activity against B. cereus and K. pneumonia, with MIC values of 3.90 μg/mL and 0.49 μg/mL, respectively. It achieves this antibacterial effect by strongly binding to specific residues of tyrosyl-tRNA synthetase [1].
价 格:¥电议型 号:T61123产 地:中国大陆
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T61122ZINC12409120;化合物ZINC12409120R-4584;R-4584
ZINC12409120 (R-4584) is a selective ERK inhibitor.ZINC12409120 inhibits ERK with an IC50 of 5.0 μM.ZINC12409120 inhibits ERK activity by interfering with FGF23:α-Klotho interaction.
价 格:¥电议型 号:T61122产 地:中国大陆
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T61121NusB-IN-1;化合物 NusB-IN-1NusB-IN-1
NusB-IN-1 (Compound 22r) is a highly effective bacterial rRNA synthesis inhibitor, administered orally. It exhibits potent antimicrobial activity against MRSA and VRSA [1].
价 格:¥电议型 号:T61121产 地:中国大陆
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T61120Carbonic anhydrase inhibitor 2;化合物 Carbonic anhydrase inhibitor 2Carbonic anhydrase inhibitor 2
Compound 7c, identified as carbonic anhydrase inhibitor 1, effectively inhibits carbonic anhydrase II. This inhibitor, also known as carbonic anhydrase inhibitor 3, lowers intraocular pressure in glaucomatous rabbits [1].
价 格:¥电议型 号:T61120产 地:中国大陆