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T61100Antileishmanial agent-4;化合物 Antileishmanial agent-4Antileishmanial agent-4
Antileishmanial agent-4, a ribonucleoside analogue, functions as an antileishmanial agent [1].
价 格:¥电议型 号:T61100产 地:中国大陆
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T6110YM-201636;化合物YM201636YM-201636
YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue.
价 格:¥电议型 号:T6110产 地:中国大陆
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T60611Talaglumetad hydrochloride;化合物 Talaglumetad hydrochlorideTalaglumetad hydrochloride
Talaglumetad hydrochloride is a prodrug of Eglumegad which is the potent and selective agonist of the type II metabotropic glutamate receptor (mGluR2/3) to treat with psychiatric disorders.
价 格:¥电议型 号:T60611产 地:中国大陆
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T4611EN300-203561;化合物EN300-203561EN300-203561
EN300-203561 has a wide range of applications in life science related research.
价 格:¥电议型 号:T4611产 地:中国大陆
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T40611(E)-Dehydrodiconiferyl alcohol;(E)-Dehydrodiconiferyl alcohol(E)-Dehydrodiconiferyl alcohol
(E)-Dehydrodiconiferyl alcohol is a potent dual inhibitor of hCA IX and hCA XII, effectively impeding the catalytic activity of both carbonic anhydrase isoforms. Additionally, (E)-Dehydrodiconiferyl alcohol exerts inhibitory effects on the nuclear translocation of NF-κB in the connective tissue of the healing area.
价 格:¥电议型 号:T40611产 地:中国大陆
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T39611EnuvaptanEnuvaptanEnuvaptan|||BAY-2327949
Enuvaptan is a vasopressin receptor antagonist and has the potential for research into renal and cardiovascular diseases.
价 格:¥电议型 号:T39611产 地:中国大陆
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T39082AL-611;AL-611AL-611
AL-611 is an HCV NS5B polymerase inhibitor ( EC 50 = 5 nM).
价 格:¥电议型 号:T39082产 地:中国大陆
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T38611Seco-DUBA;Seco-DUBASeco-DUBA
Seco-DUBA, a duocarmycin (DUBA) prodrug, possess two hydroxyl groups suitable for antibody coupling through a linker. This compound, serving as a precursor, enables the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T38611产 地:中国大陆
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T37611Methyl phenylacetate;苯乙酸甲酯Methyl 2-phenylacetate;Methyl 2-phenylacetate
Methyl phenylacetate (Methyl 2-phenylacetate) is a RIFM flavor extracted from the outer layer of fermenting mycelium.
价 格:¥电议型 号:T37611产 地:中国大陆
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T36717RWJ-56110 dihydrochloride;RWJ-56110 dihydrochlorideRWJ-56110 dihydrochloride
RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits the aggregation of human platelets induced by both SFLLRN-NH2 (IC50=0.16 μM) and thrombin (IC50=0.34 μM), quite selective relative to U46619 . RWJ-56110 dihydrochloride blocks angiogenesis and blocks the formation of new vessels in vivo. RWJ-56110 dihydrochloride induces cell ap
价 格:¥电议型 号:T36717产 地:中国大陆
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T36611(±)13-HODE;(±)13-HODE(±)13-HODE
(±)13-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. It is the principle hydroxylated fatty acid in human psoriatic skin scales, with a mean concentration of 17 ng/mg.[1]
价 格:¥电议型 号:T36611产 地:中国大陆
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T3621Brigatinib;布格替尼AP-26113;布格替尼|||AP-26113
Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor.
价 格:¥电议型 号:T3621产 地:中国大陆
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T361193-hydroxy Desloratidine;3-hydroxy Desloratidine3-hydroxy Desloratidine
3-hydroxy Desloratidine is a major metabolite of desloratadine , a tricyclic antagonist of the histamine H1 receptor.
价 格:¥电议型 号:T36119产 地:中国大陆
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T361183-hydroxy Darifenacin;3-hydroxy Darifenacin3-hydroxy Darifenacin
3-hydroxy Darifenacin is a metabolite of darifenacin . It is an antagonist of M1-5 muscarinic receptors (Kis = 17.78, 79.43, 2.24, 36.31, and 6.17 nM, respectively, in CHO cells).
价 格:¥电议型 号:T36118产 地:中国大陆
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T361173-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid;3-Deoxy-D-glycero-D-galacto-2-nonulosonic AcidDeamino
Sialic acids, commonly present as terminal carbohydrates on glycoconjugates, are essential for a variety of cellular functions including cell adhesion and signal recognition, as well as the formation and progression of tumors. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid is a deaminated sialic acid that was first identified at the nonreducing ends of oligosialyl chains in rainbow trout egg glycoprotein.[1] It is thought to be a precursor for the biosynthesis of other members of the sialic acid
价 格:¥电议型 号:T36117产 地:中国大陆
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T36116Concanamycin B;Concanamycin BConcanamycin B
Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM). In this way, it blocks the acidification of vacuolar organelles as well as early to late endosomal transport. Concanamycin B interferes with bone resorption and maturation of CD8 T lymphocytes. It also prevents processing of major histocompatibility complex (MHC) class II precursors in human B cells, inhibiting the expression of MHC class II molecules on the cell su
价 格:¥电议型 号:T36116产 地:中国大陆
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T36115Colchicoside;秋水仙碱苷3-Demethylcolchicine glucoside;3-Demethylcolchicine glucoside
Colchicoside (3-Demethylcolchicine glucoside) is extracted from Gloriosa superba and shows efficacy in a murine model of pancreatic adenocarcinoma.
价 格:¥电议型 号:T36115产 地:中国大陆
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T36114Coenzyme Q2Coenzyme Q2Coenzyme Q2|||Coenzyme Q-2
Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. In its reduced form, it acts as an antioxidant. Coenzyme Q2 is a precursor of coenzyme Q10 that has 2, rather than 10, isoprenoid units on the ubiquinone base. It can act as an electron acceptor for bacterial Complex I. In mammalian cells, exogenous coenzyme Q2 prevents the production of reactive oxygen species associated with Complex I activity. For
价 格:¥电议型 号:T36114产 地:中国大陆
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T36112Clopidogrel Carboxylic Acid (hydrochloride);Clopidogrel Carboxylic Acid (hydrochloride)Clopidogrel C
Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM). Clopidogrel inhibits ADP-induced platelet aggregation ex vivo and functions as a prodrug whereupon biotransformation to its active thiol metabolite via CYP2C19 in the liver enables its anti-aggregating activity. An estimated 15% of administered clopidogrel is metabolized by CYP2C19 to the thiol metabolite. Clopidogrel carboxylic acid i
价 格:¥电议型 号:T36112产 地:中国大陆
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T36111L-Iduronic acid sodium salt;L-艾杜糖醛酸钠L-Iduronic acid sodium salt
L-Iduronic acid sodium salt is a monosaccharide that is an important component of glycosaminoglycans (GAGs) such as heparin, heparan sulfate, and dermatan sulfate.
价 格:¥电议型 号:T36111产 地:中国大陆