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T61158Anti-infective agent 5;化合物 Anti-infective agent 5Anti-infective agent 5
Anti-infective agent 5 (compound 74) is an orally active inhibitor of Trypanosoma cruzi exhibiting an IC50 value of 0.10 μM. In addition to its potent inhibitory effect, anti-infective agent 5 demonstrates efficacy in reducing parasite burden in vivo. Consequently, this compound holds promising potential for research pertaining to infection. [1]
价 格:¥电议型 号:T61158产 地:中国大陆
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T61157ABAI-30;化合物 ABAI-30ABAI-30
ABAI-30 is a highly potent and orally bioavailable anti-inflammatory compound that efficiently suppresses nitric oxide (NO) production in lipopolysaccharide (LPS) activated RAW264.7 cells [1].
价 格:¥电议型 号:T61157产 地:中国大陆
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T61156L-Lysyl-L-lysine dihydrochloride;化合物Lysyllysine二盐酸盐Lysyllysine dihydrochloride;Lysyllysine dihydroch
L-Lysyl-L-lysine dihydrochloride (Lysyllysine dihydrochloride) is an enzyme cleavable linker. L-Lysyl-L-lysine dihydrochloride can be used as facile linker for delivering multiple biologically active peptides.
价 格:¥电议型 号:T61156产 地:中国大陆
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T61155D-Cl-amidine hydrochloride;化合物 D-Cl-amidine hydrochlorideD-Cl-amidine hydrochloride
D-Cl-amidine hydrochloride is a potent and highly selective inhibitor of PAD1. It exhibits excellent tolerance and does not induce significant toxicity [1].
价 格:¥电议型 号:T61155产 地:中国大陆
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T61154Colistin adjuvant-2;化合物 Colistin adjuvant-2Colistin adjuvant-2
Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].
价 格:¥电议型 号:T61154产 地:中国大陆
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T61153Mepazine hydrochloride;化合物 Mepazine hydrochlorideMepazine hydrochloride
Mepazine hydrochloride (Pecazine hydrochloride) is a potent and selective inhibitor of the MALT1 protease, with IC50 values of 0.83 μM for GSTMALT1 full length and 0.42 μM for GSTMALT1 325-760. It enhances apoptosis and influences the viability of ABC-DLBCL cells [1].
价 格:¥电议型 号:T61153产 地:中国大陆
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T61152FTO-IN-8;化合物 FTO-IN-8FTO-IN-8
FTO-IN-8, also known as FTO-43, is an inhibitor of N6-methyladenosine demethylase FTO (fat mass- and obesity-associated protein). It exhibits an IC50 value of 5.5 μM and displays anti-cancer cell proliferative activity [1].
价 格:¥电议型 号:T61152产 地:中国大陆
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T61151Beclobrate;贝罗贝特Sgd 24774;Sgd 24774
Beclobrate (Sgd 24774) is a novel orally available fibric acid derivative that has shown significant lipid and cholesterol-lowering activity in rodents and may be used in the study of primary hyperlipoproteinemia.
价 格:¥电议型 号:T61151产 地:中国大陆
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T61150Oleyl Mesylate;甲磺酸油酯Oleyl Mesylate
Oleyl Mesylate is a derivative of oleyl alcohol that can be incorporated into various formulations.
价 格:¥电议型 号:T61150产 地:中国大陆
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T6115Fostamatinib;福他替尼R788;R788|||福他替尼
Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.
价 格:¥电议型 号:T6115产 地:中国大陆
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T61149Antibacterial agent 121;化合物 Antibacterial agent 121Antibacterial agent 121
Antibacterial agent 121 (Compound 10) demonstrates antibacterial properties and exhibits efficacy against mycobacterial strains while also possessing anti-inflammatory activity. This compound finds potential applications in Tuberculosis (TB) research [1].
价 格:¥电议型 号:T61149产 地:中国大陆
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T61148Flutrimazole;氟曲马唑Flutrimazole
Flutrimazole is a dual-action imidazole antifungal compound, exhibiting both anti-inflammatory and antifungal properties. Notably, flutrimazole demonstrates limited transdermal penetration, making it particularly advantageous for topical applications in the treatment of fungal infections, especially those accompanied by inflammation.
价 格:¥电议型 号:T61148产 地:中国大陆
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T61147Chitin synthase inhibitor 4;几丁质合酶抑制剂4Chitin synthase inhibitor 4
Chitin synthase inhibitor 4 is a chitin synthase (CHS) inhibitor with antimicrobial activity.Chitin synthase inhibitor 4 is a CHS-based compound and a candidate fungicide.
价 格:¥电议型 号:T61147产 地:中国大陆
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T61146PIPES disodium;化合物 PIPES disodiumPIPES disodium
PIPES disodium, also known as 1,4-Piperazinediethanesulfonic acid disodium, is a crucial constituent of PIPES buffer agent utilized in the field of biochemistry [1].
价 格:¥电议型 号:T61146产 地:中国大陆
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T61145Topiramate lithium;化合物 Topiramate lithiumTopiramate lithium
Topiramate lithium (McN 4853) is a wide-ranging antiepileptic compound with GluR5 receptor antagonistic properties. Its mechanism of action involves enhancing GABAergic activity, inhibiting kainate/AMPA receptors, voltage-sensitive sodium and calcium channels, and increasing potassium conductance. Additionally, this compound inhibits carbonic anhydrase. [1][2][3]
价 格:¥电议型 号:T61145产 地:中国大陆
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T61144Hepcidin antagonist-1;Hepcidin 拮抗剂1Hepcidin antagonist-1
Hepcidin antagonist-1 is an iron-modulating antagonist.Hepcidin antagonist-1 can be used to study metabolic disorders such as iron-deficiency diseases and anemia.
价 格:¥电议型 号:T61144产 地:中国大陆
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T61143Antitubercular agent-18;化合物 Antitubercular agent-18Antitubercular agent-18
Antitubercular agent-18 (Compound 9a) is an antitubercular agent that exhibits highly selective antimycobacterial effects, with minimum inhibitory concentration (MIC) values of 2 μg/ml against M. tuberculosis H37Rv, Spec. 192, and Spec. 210, and 128 μg/ml against Spec. 800, demonstrating its efficacy in inhibiting the growth of these mycobacterial strains [1].
价 格:¥电议型 号:T61143产 地:中国大陆
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T61142Antitubercular agent-17;化合物 Antitubercular agent-17Antitubercular agent-17
Antitubercular agent-17 (Compound 8a) is an efficacious antitubercular agent, demonstrating Minimum Inhibitory Concentration (MIC) values of 2 μg/ml against M. tuberculosis H37Rv, Spec. 192, and Spec 210, and 128 μg/ml against Spec. 800. It exhibits highly selective antimycobacterial effects [1].
价 格:¥电议型 号:T61142产 地:中国大陆
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T61141Antitubercular agent-27;化合物 Antitubercular agent-27Antitubercular agent-27
Antitubercular agent-27 (compound 1) exhibits potent antitubercular properties, demonstrated by an IC50 of 3.2 μM, an MIC of 7.8 μM, and an IC90 of 7.0 μM. It effectively targets resistant Mycobacterium tuberculosis H37Rv isolates, displaying significant intracellular antimycobacterial activity with low cytotoxicity [1].
价 格:¥电议型 号:T61141产 地:中国大陆
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T61140IDO1/TDO-IN-3;化合物 IDO1/TDO-IN-3IDO1/TDO-IN-3
IDO1/TDO-IN-3 is a powerful inhibitor targeting IDO1 and TDO enzymes. It displays noteworthy effectiveness against IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM). Additionally, IDO1/TDO-IN-3 demonstrates considerable in vivo anti-tumor properties while exhibiting no apparent toxicity [1].
价 格:¥电议型 号:T61140产 地:中国大陆