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T40188HPK1-IN-20HPK1-IN-20HPK1-IN-20
HPK1-IN-19 is a potent inhibitor of hematopoietic progenitor kinase 1 (HPK1).
价 格:¥电议型 号:T40188产 地:中国大陆
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T40114RSV-IN-2;RSV-IN-2RSV-IN-2
RSV-IN-2 is a powerful compound that acts as a dual inhibitor of both wild-type and mutant respiratory syncytial virus (RSV) fusion proteins. It efficiently inhibits the activity of these proteins, with an EC50 value of 0.27 nM for the wild-type and 0.70 nM for the D486N-mutant protein.
价 格:¥电议型 号:T40114产 地:中国大陆
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T40069SENP1-IN-2SENP1-IN-2SENP1-IN-2
SENP1-IN-2, a distinct inhibitor of the deSUMOylation protease 1 (SENP1), is designed to enhance tumor radiosensitivity.
价 格:¥电议型 号:T40069产 地:中国大陆
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T3S0208Hederagenin 28-O-beta-D-glucopyranosyl ester;常春苷元-28-BETA-D-吡喃葡萄糖苷Hederagenin-28-beta-D-glucopyranos
Hederagenin-28-beta-D-glucopyranoside, a triterpene saponin isolated from Ilex cornuta, protects cardiac myocytes against H2O2-induced damage.
价 格:¥电议型 号:T3S0208产 地:中国大陆
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T39990HDAC-IN-26;HDAC-IN-26HDAC-IN-26
HDAC-IN-26 is a highly selective class I HDAC inhibitor with an EC 50 value of 4.7 nM.
价 格:¥电议型 号:T39990产 地:中国大陆
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T39966SGLT1/2-IN-2SGLT1/2-IN-2SGLT1/2-IN-2
SGLT1/2-IN-2 is a chemical compound with robust dual inhibitory properties, exhibiting potent activities against SGLT1 (IC50 = 96 nM) and SGLT2 (IC50 = 1.3 nM).
价 格:¥电议型 号:T39966产 地:中国大陆
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T39961Bcl-2-IN-2;Bcl-2-IN-2Bcl-2-IN-2
Bcl-2-IN-2 is a highly potent and selective inhibitor targeting Bcl-2 and Bcl-xL. It displays an IC50 value of 0.034 nM, suggesting its strong inhibitory activity specifically against Bcl-2. Additionally, Bcl-2-IN-2 exhibits an IC50 value of 43 nM against Bcl-xL, demonstrating over 1000-fold selectivity for Bcl-2 compared to Bcl-xL.
价 格:¥电议型 号:T39961产 地:中国大陆
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T39864CDK7-IN-2 hydrochloride hydrateCDK7-IN-2 hydrochloride hydrateCDK7-IN-2 hydrochloride hydrate
CDK7-IN-2 hydrochloride hydrate (Example 6) is a highly effective and specific inhibitor of the CDK7 enzyme. This compound exhibits significant anti-cancer properties.
价 格:¥电议型 号:T39864产 地:中国大陆
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T39783DENV-IN-2;DENV-IN-2DENV-IN-2
DENV-IN-2 is a highly effective inhibitor of dengue viral replication with a potency indicated by an EC 50 of 0.016 nM. It exhibits significant activity against all four serotypes of the Dengue virus, with EC 50 values ranging from 0.013 to 0.029 nM.
价 格:¥电议型 号:T39783产 地:中国大陆
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T39752CDK12-IN-2;化合物CDK12-IN-2CDK12 inhibitor 2|||CDK12-IN-2;CDK12 inhibitor 2|||CDK12-IN-2
CDK12-IN-2 (CDK12 inhibitor 2) is an effective and selective inhibitor of CDK12 with an IC50 of 52 nM, >100 μM, >10 μM and 16 μM for CDK12, CDK2, CDK7, and CDK9. CDK12-IN-2 can be used in studies about the function of CDK12.
价 格:¥电议型 号:T39752产 地:中国大陆
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T39751MYC-IN-2;MYC-IN-2MYC-IN-2
MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.
价 格:¥电议型 号:T39751产 地:中国大陆
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T39528PCSK9-IN-2PCSK9-IN-2PCSK9-IN-2
PCSK9-IN-2 is a newly developed small molecule that effectively inhibits the protein-protein interaction (PPI) between PCSK9 and LDLR. It has been found to have a potent inhibitory activity with an IC50 value of 7.57 μM.
价 格:¥电议型 号:T39528产 地:中国大陆
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T39417ACAT-IN-2;ACAT-IN-2ACAT-IN-2
ACAT-IN-2 is a potent inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). This compound effectively blocks NF-κB mediated transcription.
价 格:¥电议型 号:T39417产 地:中国大陆
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T39389KDM2B-IN-2;化合物KDM2B-IN-2KDM2B-IN-2;KDM2B-IN-2
KDM2B-IN-2 is a potent histone demethylase (kdm2b) inhibitor.
价 格:¥电议型 号:T39389产 地:中国大陆
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T39386(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid;(3β,7β,12β,20Z)-3,7,1
(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid, a lanostane triterpenoid, demonstrates significant inhibitory effects on nitric oxide (NO) production in BV-2 microglia cells induced by n LPS, with an IC50 value of 9.55 uM. Moreover, this compound possesses anti-inflammatory properties.
价 格:¥电议型 号:T39386产 地:中国大陆
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T3938515a-Hydroxy-3,11,23-trioxo-lanost-8,20-dien-26-oic acid;15a-Hydroxy-3,11,23-trioxo-lanost-8,20-dien-
15a-Hydroxy-3,11,23-trioxo-lanost-8,20-dien-26-oic acid is a Lanostane triterpenoid compound with the ability to inhibit NO production in LPS-induced microglia.
价 格:¥电议型 号:T39385产 地:中国大陆
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T388923,11,15,23-Tetraoxo-27ξ-lanosta-8,16-dien-26-oic acid;3,11,15,23-Tetraoxo-27ξ-lanosta-8,16-dien-26-o
3,11,15,23-Tetraoxo-27ξ-lanosta-8,16-dien-26-oic acid, a lanostane-type triterpenoid extracted from Antrodia camphorate, is a chemical compound.
价 格:¥电议型 号:T38892产 地:中国大陆
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T38841IRE1α kinase-IN-2;IRE1α kinase-IN-2IRE1α kinase-IN-2;IRE1α kinase-IN-2
IRE1α kinase-IN-2 is a highly potent inhibitor of IRE1α kinase, demonstrating an EC50 of 0.82 μM. It effectively impedes IRE1α kinase autophosphorylation with an IC50 of 3.12 μM. Additionally, IRE1α kinase-IN-2 effectively inhibits the splicing of XBP1 mRNA in wild-type cell lines.
价 格:¥电议型 号:T38841产 地:中国大陆
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T38469(Rac)-Z-Phe-Phe-FMK;化合物(Rac)-Z-Phe-Phe-FMKCathepsin L-IN-2;Cathepsin L-IN-2
(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .
价 格:¥电议型 号:T38469产 地:中国大陆
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T38351DYn-2DYn-2DYn 2|||DYn2
Mild oxidation can convert the sulfhydryl group of cysteine residues on proteins to cysteine-sulfenic acid derivatives (Cys-SOH). Protein sulfenylation, then, is a post-translational modification that is relevant to redox signaling. DYn-2 is a chemoselective probe for detecting sulfenylated proteins in intact cells. DYn-2 consists of 1,3-cyclohexanedione coupled to an alkyne moiety by a 3-carbon spacer. The cyclohexanedione group selectively reacts with protein sulfenic acid modifications. The a
价 格:¥电议型 号:T38351产 地:中国大陆