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T14969CINPA1CINPA1
CINPA1 can be used as a molecular tool for understanding CAR function and it also is an inhibitor of constitutive androstane receptor (CAR). Which does not activate pregnane X receptor (PXR). CINPA1 reduces CAR-mediated transcription (IC50: ~70 nM).
价 格:¥电议型 号:T14969产 地:美洲
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T2100CX5461CX5461
CX-5461, a selective inhibitor of rRNA synthesis, suppresses Pol I-driven transcription of rRNA.
价 格:¥电议型 号:T2100产 地:美洲
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T2256CNX-1351CNX-1351,CNX1351,CNX 1351
CNX-1351 is a potent and isoform-selective targeted covalent PI3Kα inhibitor.
价 格:¥电议型 号:T2256产 地:美洲
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T2310CHIR-99021CHIR-99021,CHIR99021,CHIR 99021
CHIR-99021 (CT99021) is a GSK-3α/β inhibitor (IC50: 10/6.7 nM).
价 格:¥电议型 号:T2310产 地:美洲
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T2448CH 223191CH 223191
CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR).
价 格:¥电议型 号:T2448产 地:美洲
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T5347CXD-101CXD-101
CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101 has no activity against HDAC class II
价 格:¥电议型 号:T5347产 地:美洲
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T5393CK1-IN-1CK1-IN-1,PUN51207,
CK1-IN-1, compound 1c reported in patent WO2015119579A1, is a casein kinase 1 (CK1) inhibitor. It has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively.
价 格:¥电议型 号:T5393产 地:美洲
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T5996CB1-IN-1CB1-IN-1,DBPR211,
CB1-IN-1 is a peripherally restricted CB1R antagonist, for CB1R and CB2R with Ki of 0.3 nM and 21 nM,respectively.
价 格:¥电议型 号:T5996产 地:美洲
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T6091CP-673451CP-673451,CP673451,CP 673451
CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than other angiogenic receptors.
价 格:¥电议型 号:T6091产 地:美洲
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T6488Epinastine HClEpinastine HCl,WAL-801CL HCl,Alesion
Epinastine is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.
价 格:¥电议型 号:T6488产 地:美洲
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T8652CASP3 Activator 1541;化合物CASP3 Activator 1541CASP3 Activator 1541
CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.
价 格:¥电议型 号:T8652产 地:中国大陆
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T8596Ceefourin 1;化合物Ceefourin 1Ceefourin 1
Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.
价 格:¥电议型 号:T8596产 地:中国大陆
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T83957CELT-211;化合物 CELT-211CELT-211
CELT-211 is a potent, selective fluorescent ligand for the h5HT2B serotonin receptor, demonstrating full selectivity over h5HT2A and h5HT2C receptors with a Ki value of 56.3 nM in radioligand binding assays for h5HT2B receptors. Its excitation and emission maxima are 589 nm and 616 nm, respectively, making its wavelengths compatible with its application as an acceptor dye in Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assays when paired with the CoraFluor 1 TR-FRET donor.
价 格:¥电议型 号:T83957产 地:中国大陆
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T82789Caloxin 1B1;化合物 Caloxin 1B1Caloxin 1B1
Caloxin 1B1, a bioactive peptide, exhibits selective inhibition of PMCA extracellularly by binding preferentially to the extracellular domain 1 of PMCA4 over PMCA1. Identified through a screening process for its high-affinity interaction with PMCA, Caloxin 1B1 is capable of direct application to cells and tissues, facilitating research into its impact on smooth muscle and endothelium.
价 格:¥电议型 号:T82789产 地:中国大陆
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T82778Cardioexcitatory peptide 1;化合物 Cardioexcitatory peptide 1Cardioexcitatory peptide 1
Cardioexcitatory peptide 1, a potent neuropeptide derived from Achatina atria, exerts significant excitatory effects on cardiac function, additionally influencing the motility of muscular tissues and neural activities [1].
价 格:¥电议型 号:T82778产 地:中国大陆
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T82776Cartilostatin 1;化合物 Cartilostatin 1Cartilostatin 1
Cartilostatin 1, an anti-angiogenic peptide, has potential applications in research focused on angiogenesis inhibition [1].
价 格:¥电议型 号:T82776产 地:中国大陆
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T82765CcpA-IN-1;化合物 CcpA-IN-1CcpA-IN-1
CcpA-IN-1 is a Staphylococcus aureus antibiotic exhibiting significant bactericidal activity (MICs=460 nM) [1].
价 格:¥电议型 号:T82765产 地:中国大陆
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T82758CDK9-Cyclin T1 PPI-IN-1;化合物 CDK9-Cyclin T1 PPI-IN-1CDK9-Cyclin T1 PPI-IN-1
CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin T1 protein-protein interaction (PPI), suppressing cell proliferation in TNBC MDA-MB-231 cells with an IC50 of 0.044 μM and inducing apoptosis. This compound diminishes CDK9 transcriptional activity and downregulates phosphorylation of RNA Pol II CTD ser2. In vivo, CDK9-Cyclin T1 PPI-IN-1 effectively impedes tumor growth in a TNBC 4T1 mouse model [1].
价 格:¥电议型 号:T82758产 地:中国大陆
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T82745Cereblon inhibitor 1;化合物 Cereblon inhibitor 1Cereblon inhibitor 1
Cereblon inhibitor 1, an isoindoline derivative, serves as a modulator of the cereblon E3 ubiquitin ligase and shows promise for applications in cancer research.
价 格:¥电议型 号:T82745产 地:中国大陆