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  • T73127C16-K-cBB1；化合物 C16-K-cBB1C16-K-cBB1

    C16-K-cBB1 is a potent, selective antimicrobial agent effective against Methicillin-resistant Staphylococcus aureus (MRSA), demonstrated by its minimal inhibitory concentration (MIC) of 1 ?g/mL. This compound exhibits excellent selectivity with minimal hemolytic activity, and can eradicate MRSA cells within 120 minutes when applied at a concentration of 12.5 μg/mL.

    价 格：￥电议型 号：T73127产 地：中国大陆

  • T72849CB2R agonist 1；化合物 CB2R agonist 1CB2R agonist 1

    CB2R agonist 1, a selective ligand for the cannabinoid receptor subtype 2 (CB2R), demonstrates a high affinity and excellent selectivity, with an EC50 value of 0.56 ?M, favoring human CB2R over CB1R. It plays an immunomodulatory role by regulating the production of both pro-inflammatory and anti-inflammatory cytokines.

    价 格：￥电议型 号：T72849产 地：中国大陆

  • T72699Cavα2δ1&NET-IN-1；化合物 Cavα2δ1&NET-IN-1Cavα2δ1&NET-IN-1

    Cavα2δ1&NET-IN-1 . Cavα2δ1&NET-IN-1 inhibits Ca v α2δ-1 with a K i of 112 nM. Cavα2δ1&NET-IN-1 inhibits NET with a K i of 383 nM and IC 50 of 67 nM. Cavα2δ1&NET-IN-1 can be used for research of pain [1] .

    价 格：￥电议型 号：T72699产 地：中国大陆

  • T72654(R)-PD 0325901CL；化合物 (R)-PD 0325901CL(R)-PD 0325901CL

    (R)-PD 0325901CL, an isomer of PD 0325901CL, acts as a selective inhibitor of mitogen-activated protein kinase kinase (MEK), playing a crucial role in cancer research. It effectively inhibits the growth of cancer cells both in vitro and in vivo.

    价 格：￥电议型 号：T72654产 地：中国大陆

  • T72605C-RAF kinase-IN-1；化合物 C-RAF kinase-IN-1C-RAF kinase-IN-1

    C-RAF kinase-IN-1 is a potent inhibitor of C-RAF kinase with an IC 50 of 0.193 μM. C-RAF kinase-IN-1 is a quinoline derivative. C-RAF kinase-IN-1 has the potential for the research of cancer diseases [1] .

    价 格：￥电议型 号：T72605产 地：中国大陆

  • T72569Cathepsin L/S-IN-1；化合物 Cathepsin L/S-IN-1Cathepsin L/S-IN-1

    Cathepsin L/S-IN-1, a dual inhibitor targeting Cathepsin L and Cathepsin S, exhibits potent and selective inhibition with IC50 values of 4.10 μM and 1.79 μM, respectively. Demonstrating significant antimetastatic and invasive effects, it effectively impacts pancreatic cancer BxPC-3 and PANC-1 cells.

    价 格：￥电议型 号：T72569产 地：中国大陆

  • T72505CTP Synthetase-IN-1；CTP Synthetase 抑制剂 1CTP Synthetase-IN-1

    CTP Synthetase-IN-1 is an orally active and potent cytidine 5´-triphosphate synthetase (CTPS) inhibitor with potential antitumour activity, shows anti-inflammatory activity in animal models of inflammation, inhibits human CTPS1 and human CTPS2, and can be used in studies of arthritis and rheumatoid arthritis.

    价 格：￥电议型 号：T72505产 地：中国大陆

  • T72501CYP4A11/CYP4F2-IN-1；CYP4A11/CYP4F2 抑制剂 1CYP4A11/CYP4F2-IN-1

    CYP4A11/CYP4F2-IN-1 is a cytochrome P450 (CYP) 4A11 and CYP4F2 inhibitor. CYP4A11/CYP4F2-IN-1 can be used to study kidney diseases and cardiovascular and cerebrovascular diseases.

    价 格：￥电议型 号：T72501产 地：中国大陆

  • T72407c-Met/MEK1/Flt-3-IN-1；化合物 c-Met/MEK1/Flt-3-IN-1c-Met/MEK1/Flt-3-IN-1

    Antiproliferative Against-3 (comp 33) demonstrates significant activity against Hela (IC 50 = 0.21 ?M), A549 (IC 50 = 0.39 ?M), and MCF-7 (IC 50 = 0.33 ?M) cell lines. Additionally, it induces apoptosis in a dose-dependent manner by arresting A549 cells in the G1 phase.

    价 格：￥电议型 号：T72407产 地：中国大陆

  • T72328Cyclopropenone probe 1；化合物 Cyclopropenone probe 1Cyclopropenone probe 1

    Cyclopropenone probe 1 can specifically and efficiently modify a triple-negative breast cancer driver, glutathione S-transferase pi-1 (GSTP1) , by covalently binding at the catalytic active site.

    价 格：￥电议型 号：T72328产 地：中国大陆

  • T71902CHEMBL94431；化合物 CHEMBL94431CHEMBL94431

    CHEMBL94431 is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase.

    价 格：￥电议型 号：T71902产 地：中国大陆

  • T71870CP21；化合物 CP21CP21

    CP21 is an iron chelator that binds to iron in a 3:1 (ligand:iron) ratio. It is active against P. falciparum when used at concentrations of 10 and 100 ?M. CP21 inhibits production of prostaglandin I2 induced by epinephrine, arachidonic acid, or A23187 in isolated rat aortic rings with IC50 values of 1.3, 1.3, and 1.4 mM, respectively. It inhibits glutamate-induced oxytosis, as well as decreases iodoacetic acid-induced cytotoxicity in an in vitro model of ischemia, in HT22 mouse hippocampal cells

    价 格：￥电议型 号：T71870产 地：中国大陆

  • T71799CAP-1；化合物 CAP-1CAP-1

    CAP-1 is an inhibitor of HIV-1 capsid formation.

    价 格：￥电议型 号：T71799产 地：中国大陆

  • T71793CDMG1；化合物 CDMG1CDMG1

    CDMG1 is a novel Wnt inhibitor, promoting heart regeneration, injury repair, and myocardial hyperplasia through expansion of the cardiac progenitor cell population

    价 格：￥电议型 号：T71793产 地：中国大陆

  • T71627CX-5011；化合物 CX-5011CX-5011

    CX-5011, a CK2 inhibitor, induces Rac1 activation and promotes apoptosis, effectively causing cancer cell death [1] [2].

    价 格：￥电议型 号：T71627产 地：中国大陆

  • T71534LCIA-1 (Free base)；化合物CIA-1CIA-1(Free base）；CIA-1(Free base）

    CIA-1 (Free base) is a nuclear receptor COUP-TFII inhibitor with IC50 values ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines. CIA-1 (Free base) inhibits tumor growth in a mouse model of prostate cancer xenografts.

    价 格：￥电议型 号：T71534L产 地：中国大陆

  • T71362GCC-4401C free base；化合物 GCC-4401C free baseGCC-4401C free base

    GCC-4401C free base is a factor Xa inhibitor similar to rivaroxaban that is currently under development for venous thromboembolic disease (VTE).

    价 格：￥电议型 号：T71362产 地：中国大陆

  • T71096GCC-4401C methanesulfonate；化合物 GCC-4401C methanesulfonateGCC-4401C methanesulfonate

    GCC-4401C methanesulfonate is a factor Xa inhibitor similar to rivaroxaban that is currently under development for venous thromboembolic disease (VTE).

    价 格：￥电议型 号：T71096产 地：中国大陆

  • T70920CGS 24891；化合物 CGS 24891CGS 24891

    CGS 24891 is a 5-lipoxygenase inhibitor.

    价 格：￥电议型 号：T70920产 地：中国大陆

  • T70811CRV431；化合物 CRV431CRV431

    CRV431 is a novel Pan-Cyclophilin Inhibitor, potently inhibiting all cyclophilin isoforms tested - A, B, D, and G (IC50 values ranged from 1-7 nM).

    价 格：￥电议型 号：T70811产 地：中国大陆

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