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T62736Cas9-IN-1;化合物 Cas9-IN-1Cas9-IN-1
Cas9-IN-1 is a potent inhibitor of Cas9 with an IC50 value of 7.02 μM. Cas9-IN-1 acts by binding apo-Cas9 and blocking the formation of the Cas9:gRNA complex.
价 格:¥电议型 号:T62736产 地:中国大陆
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T62631CB2 receptor antagonist 1;化合物 CB2 receptor antagonist 1CB2 receptor antagonist 1
Hexyl resorcinol derivative 29 is a CB2 selective competitive antagonist/reverse agonist demonstrating notable potency. Meanwhile, Olivanol and 5-(2-methyloctane-2-yl) resorcinol derivatives 23 and 24 exhibit substantial antinociceptive effects. Notably, compound 24 activates both cannabinoid and TRPV1 receptors.
价 格:¥电议型 号:T62631产 地:中国大陆
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T62612CD33 splicing modulator 1;化合物 CD33 splicing modulator 1CD33 splicing modulator 1
CD33 splicing modulator 1 (Compound 1) is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid cell surface receptor known to regulate microglial cell activity. CD33 splicing modulator 1 has potential for the study of neurodegenerative diseases, including Alzheimer´s disease.
价 格:¥电议型 号:T62612产 地:中国大陆
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T62586Cav 2.2/3.2 blocker 1;化合物 Cav 2.2/3.2 blocker 1Cav 2.2/3.2 blocker 1
Cav 2.2/3.2 blocker 1 (Compound 9e) is a neuronal calcium channel blocker that acts on Cav2.2 (IC50: 1.22 μM) and Cav3.2 (IC50: 80 μM). Can penetrate the central nervous system.
价 格:¥电议型 号:T62586产 地:中国大陆
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T62583CBR Agonist-1;化合物 CBR Agonist-1CBR Agonist-1
CBR Agonist-1 (27a-cis) is a cannabinoid receptor (CBR) agonist that acts on CB1R (Ki: 0.18 μM) and CB2R (Ki: 1.22 μM). CBR Agonist-1 (27a-cis) can be used to study endogenous cannabinoid system-related diseases.
价 格:¥电议型 号:T62583产 地:中国大陆
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T62468CB1/2 agonist 1;化合物 CB1/2 agonist 1CB1/2 agonist 1
CB1/2 agonist 1 is a potent CB1/2 agonist that crosses the blood-brain barrier, acting on CB1R (EC50: 56.15 nM) and CB2R (EC50: 11.63 nM). CB1/2 agonist 1 reduces glutamate release and LPS-induced microglia activation, and has anti-inflammatory and analgesic activities. CB1/2 agonist 1 has potential for multiple sclerosis studies.
价 格:¥电议型 号:T62468产 地:中国大陆
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T62387CA IX-IN-1;化合物 CA IX-IN-1CA IX-IN-1
CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) that exhibits antitumour effects.
价 格:¥电议型 号:T62387产 地:中国大陆
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T62337CDK2-IN-11;化合物 CDK2-IN-11CDK2-IN-11
CDK2-IN-11 (compound 9d) is a potent inhibitor of CDK2 (IC50: 6.4 μM) and acts on hCA II (Ki: 23.4 nM), hCA IX (Ki: 56.3 nM) and hCA XII (Ki: 44.3 nM). CDK2-IN-11 can be used in anticancer studies.
价 格:¥电议型 号:T62337产 地:中国大陆
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T62259COX-2-IN-21;化合物 COX-2-IN-21COX-2-IN-21
COX-2-IN-21 (Compound 5c) is an orally active, selective COX-2 inhibitor (IC50: 0.039 μM). COX-2-IN-21 has good anti-inflammatory potential.
价 格:¥电议型 号:T62259产 地:中国大陆
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T62231Cdc7-IN-11;化合物 Cdc7-IN-11Cdc7-IN-11
Cdc7-IN-11 is a potent inhibitor of Cdc7 (IC50 ≤ 1 nM) and can be used in the study of proliferative diseases.
价 格:¥电议型 号:T62231产 地:中国大陆
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T62125Colistin adjuvant-1;化合物 Colistin adjuvant-1Colistin adjuvant-1
Colistin adjuvant-1 is a mucin adjuvant with enhanced mucin-enhancing activity against gram-negative bacteria. colistin adjuvant-1 exhibits inhibition of NF-κB (IC50: 0.209 μM).
价 格:¥电议型 号:T62125产 地:中国大陆
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T62103COX-2/PI3K-IN-1;化合物 COX-2/PI3K-IN-1COX-2/PI3K-IN-1
COX-2/PI3K-IN-1 (compound 5d) is a potent inhibitor of PI3K (IC50: 1.14 nM). COX-2/PI3K-IN-1 is a selective inhibitor of COX-2 (Ki: 3.24 nM).
价 格:¥电议型 号:T62103产 地:中国大陆
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T62068Chitin synthase inhibitor 1;化合物 Chitin synthase inhibitor 1Chitin synthase inhibitor 1
Chitin synthase inhibitor 1 is a potent and selective chitin synthase (CHS) inhibitor with IC50 of 0.12 mM. Chitin synthase inhibitor 1 potently inhibits drug-resistant fungi variants.
价 格:¥电议型 号:T62068产 地:中国大陆
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T6206PHA-767491;化合物PHA767491CAY10572|||PHA767491|||PHA 767491;CAY10572|||PHA767491|||PHA 767491
PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.
价 格:¥电议型 号:T6206产 地:中国大陆
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T62016CB1R Allosteric modulator 1;化合物 CB1R Allosteric modulator 1CB1R Allosteric modulator 1
CB1R Allosteric modulator 1 (compound 11) is a potent allosteric modulator of CB1R. CB1R Allosteric modulator 1 negatively affects the functional activity of orthosteric ligands (NAM) at CB1Rs.
价 格:¥电议型 号:T62016产 地:中国大陆
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T62007CXCR4 modulator-1;化合物 CXCR4 modulator-1CXCR4 modulator-1
CXCR4 modulator-1 (compound ZINC72372983) is a potent CXCR4 modulator (EC 50= 100 nM). CXCR4 modulator-1 has research value in anti-inflammatory, anticancer and anti-HIV.
价 格:¥电议型 号:T62007产 地:中国大陆
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T61989CB1R antagonist 1;CB1R拮抗剂1CB1R antagonist 1
CB1R antagonist 1 is a potent CB1R antagonist that can be used to study diseases related to the nervous system.
价 格:¥电议型 号:T61989产 地:中国大陆
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T61926AKR1C3-IN-8;化合物 AKR1C3-IN-8AKR1C3-IN-8
AKR1C3-IN-8 (Compound 5) is an effective and selective AKR1C3 inhibitor (IC50=0.069 μM). AKR1C3-IN-8 has antitumor activity.
价 格:¥电议型 号:T61926产 地:中国大陆
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T61925AKR1C3-IN-7;化合物 AKR1C3-IN-7AKR1C3-IN-7
AKR1C3-IN-7 (Compound 13) is an effective and selective AKR1C3 inhibitor (IC50=0.19 μM). AKR1C3-IN-7 has antitumor activity.
价 格:¥电议型 号:T61925产 地:中国大陆
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T61790AKR1C3-IN-6;化合物 AKR1C3-IN-6AKR1C3-IN-6
AKR1C3-IN-6 (Compound 1) is a powerful and specific inhibitor of AKR1C3, with IC50 values of 0.31 μM and 73.23 μM against AKR1C3 and AKR1C2, respectively. It demonstrates significant antitumor activity [1].
价 格:¥电议型 号:T61790产 地:中国大陆