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  • T70650Caspase-6-IN-1；化合物 Caspase-6-IN-1Caspase-6-IN-1

    Caspase-6-IN-1 is a novel Allosteric Inhibitor of Caspase-6 Activation, blocking the interaction between C6 and mHTT1-586.

    价 格：￥电议型 号：T70650产 地：中国大陆

  • T70604ClpB-IN-1；化合物ClpB-IN-1ClpB-IN-1

    ClpB-IN-1 is a potential antimicrobial agent.ClpB-IN-1 is a potent ClpB inhibitor.

    价 格：￥电议型 号：T70604产 地：中国大陆

  • T70557Cryosim-1；化合物 Cryosim-1Cryosim-1

    Cryosim-1 is a TRPM8 agonist.

    价 格：￥电议型 号：T70557产 地：中国大陆

  • T70321CBB3001；化合物 CBB3001CBB3001

    CBB3001 is a selective lysine-specific histone demethylase LSD1 inhibitor.

    价 格：￥电议型 号：T70321产 地：中国大陆

  • T70211CAM741；化合物 CAM741CAM741

    CAM741 is a novel selective inhibitor of vascular cell adhesion molecule 1 (VCAM1) synthesis in endothelial cells, blocking the process of cotranslational translocation, which is dependent on the signal peptide of VCAM1.

    价 格：￥电议型 号：T70211产 地：中国大陆

  • T70126CJM-061；化合物 CJM-061CJM-061

    CJM-061 is a Wee1 inhibitor.

    价 格：￥电议型 号：T70126产 地：中国大陆

  • T69941CMX-521；化合物 CMX-521CMX-521

    CMX521 is an antiviral drug candidate, which was developed for the treatment of norovirus, though it also shows efficacy against related viral diarrheas such as rotovirus and some sapoviruses, astroviruses and adenoviruses. It is a nucleoside analogue which acts as an inhibitor of viral RNA-dependant RNA polymerase.

    价 格：￥电议型 号：T69941产 地：中国大陆

  • T69091CBP501；化合物 CBP501CBP501

    CBP501 is a peptide with G2 checkpoint-abrogating activity. G2 checkpoint inhibitor CBP501 inhibits multiple serine/threonine kinases, including MAPKAP-K2, C-Tak1, and CHK1, that phosphorylate serine 216 of the dual-specific phosphatase Cdc25C (cell division checkpoint 25 C); disruption of Cdc25C activity results in the inhibition of Cdc25C dephosphorylation of the mitotic cyclin-dependent kinase complex Cdc2/cyclin B, preventing entry into the mitotic phase of the cell cycle.

    价 格：￥电议型 号：T69091产 地：中国大陆

  • T68711Cgs 11361；化合物 Cgs 11361Cgs 11361

    Cgs 11361 is a GABA-A receptor antagonist.

    价 格：￥电议型 号：T68711产 地：中国大陆

  • T68680CP-53631；化合物 CP-53631CP-53631

    CP-53631 is a selective serotonin reuptake inhibitor (SSRI)

    价 格：￥电议型 号：T68680产 地：中国大陆

  • T68520Cl-Necrostatin-1；化合物 Cl-Necrostatin-1Cl-Necrostatin-1

    Cl-Necrostatin-1 is an inhibitor of receptor-interacting protein kinase. It inhibits RIPK1 activity.

    价 格：￥电议型 号：T68520产 地：中国大陆

  • T67896CB2R/FAAHu00A0modulator-1；CB2R/FAAH调节剂-1CB2R/FAAHu00A0modulator-1

    CB2R/FAAH?modulator-1, a cannabinoid type 2 receptor (CB2R) agonist, is also a fatty acid amide hydrolase (FAAH) inhibitor (IC50=4 μM) that reduces the production of pro-inflammatory and anti-inflammatory cytokines and is commonly used in inflammation studies. The Kis for CB2R and CB1R are 14.8 nM and 241.3 nM, respectively.

    价 格：￥电议型 号：T67896产 地：中国大陆

  • T67846AKR1C3-IN-9；化合物AKR1C3-IN-9AKR1C3-IN-9

    AKR1C3-IN-9 is a selective Aldo-keto Reductase 1C3 (AKR1C3) inhibitor (IC50= 8.92 nM). AKR1C3-IN-9 can significantly reverse the Doxorubicin (DOX) resistance in a resistant breast cancer cell line.

    价 格：￥电议型 号：T67846产 地：中国大陆

  • T6488Epinastine hydrochloride；依匹斯汀盐酸盐Alesion|||Epinastine HCl|||WAL-801CL HCl|||Elestat；Alesion|||Epinast

    Epinastine hydrochloride (WAL-801CL HCl) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.

    价 格：￥电议型 号：T6488产 地：中国大陆

  • T64306CXCR4 probe 1；化合物 CXCR4 probe 1CXCR4 probe 1

    CXCR4 probe 1 (compound 5) is a potent and specific CXCR4-targeted PET tracer that acts on the CXCR4-specific antagonist TN14003 (IC50: 6.9 nM). The CXCR4 probe 1 has potential as a CXCR4-specific imaging probe for the diagnosis and prognostic monitoring of inflammatory diseases, CXCR4-positive tumours and metastatic tumours.

    价 格：￥电议型 号：T64306产 地：中国大陆

  • T64193AKR1C3-IN-5；化合物 AKR1C3-IN-5AKR1C3-IN-5

    AKR1C3-IN-5 (Compound 6e) is a potent inhibitor of AKR1C3, derived from drupanin. AKR1C3 enzymes are overexpressed in hormone-dependent prostate and breast tumours. AKR1C3-IN-5 is able to act on MCF-7 cells (IC50: 9.6 ± 3 μM; SI: 5.5).

    价 格：￥电议型 号：T64193产 地：中国大陆

  • T64154CYP51/HDAC-IN-1；化合物 CYP51/HDAC-IN-1CYP51/HDAC-IN-1

    CYP51/HDAC-IN-1 is an orally active, potent, dual CYP51/HDAC inhibitor that inhibits important virulence factors and down-regulates the expression of associated drug resistance genes.CYP51/HDAC-IN-1 has shown effective therapeutic effects in both Candidiasis tropicalis and Cryptococcal meningitis.

    价 格：￥电议型 号：T64154产 地：中国大陆

  • T63954CYP3A4-IN-1；化合物 CYP3A4-IN-1CYP3A4-IN-1

    CYP3A4-IN-1 is a potent inhibitor of cytochrome P450 3A4 (CYP3A4) (IC50: 0.085 μM).

    价 格：￥电议型 号：T63954产 地：中国大陆

  • T63851CDK9/10/GSK3β-IN-1；化合物 CDK9/10/GSK3β-IN-1CDK9/10/GSK3β-IN-1

    CDK9/10/GSK3β-IN-1 is a kinase inhibitor (Flavopiridol analogue) that effectively inhibits HsGSK3β, HsCDK9/CyclinT, HsCDK5/p25 and HsCDK2/CyclinA with IC50 values of 59 nM, 64 nM, 1.093 μM and 1.725 μM, respectively. CDK9/10/GSK3β-IN-1 exhibited comparable or higher anti-cancer cell activity than Flavopiridol and showed high anti-proliferative activity against up to seven cancer cell lines in vitro.

    价 格：￥电议型 号：T63851产 地：中国大陆

  • T63808Cap-dependent endonuclease-IN-1；帽依赖性核酸内切酶-IN-1Cap-dependent endonuclease-IN-1

    Cap-dependent endonuclease-IN-1 is a highly potent and orally active cap-dependent endonuclease inhibitor with antiviral activity for the study of influenza virus infection.

    价 格：￥电议型 号：T63808产 地：中国大陆

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