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T83010Antitumor agent-106;化合物 Antitumor agent-106Antitumor agent-106
Antitumor Agent-106 (Compound 42) is a potent anticancer compound, demonstrating significant inhibitory activity (IC50 = 4.2-6.6 ?M) against lung and colon cancer cell lines [1].
价 格:¥电议型 号:T83010产 地:中国大陆
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T82989AP-C6;化合物 AP-C6AP-C6
AP-C6 is a potent inhibitor of guanosine 3´,5´-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 of 6.5. It inhibits human cGKII activity in vitro in a concentration-dependent manner and potentiates cAMP signaling through phosphodiesterase (PDE) inhibition [1].
价 格:¥电议型 号:T82989产 地:中国大陆
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T82947Atinumab;化合物 AtinumabATI355|||6A3-IgG4;ATI355|||6A3-IgG4
Atinumab (6A3-IgG4), an antibody, has potential applications in spinal cord injury (SCI) research [1].
价 格:¥电议型 号:T82947产 地:中国大陆
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T81410Prafnosbart;化合物 PrafnosbartDS-6016A;DS-6016A
Prafnosbart (DS-6016A) is a humanized IgG1-kappa monoclonal antibody targeting ACVR1 (activin A receptor type 1, ACVRLK2, ALK2, ACVR1A, SKR1), utilized in research on bone metabolism disorders [1].
价 格:¥电议型 号:T81410产 地:中国大陆
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T80900Unasnemab;化合物 UnasnemabMT-3921|||rH116A3;MT-3921|||rH116A3
Unasnemab (MT-3921), a humanized IgG1 monoclonal antibody, targets repulsive guidance molecule A (RGMa) to enhance locomotor function and support neuroregeneration, showing potential for spinal cord injury research [1].
价 格:¥电议型 号:T80900产 地:中国大陆
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T80300Aurein 2.6;化合物 Aurein 2.6Aurein 2.6
Aurein 2.6, an antibiotic antimicrobial peptide, exhibits activity against various Gram-positive bacteria with minimum inhibitory concentrations (MIC) of 25, 25, 30, 25, and 30 μM for M. luteus, S. aureus, S. epidermis, S. mutans, and B. subtilis, respectively [1][2].
价 格:¥电议型 号:T80300产 地:中国大陆
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T80011AChE-IN-46;化合物 AChE-IN-46AChE-IN-46
AChE-IN-46 (compound 4), a β-cyclocostunolide, functions as an acetylcholinesterase (AChE) inhibitor [1].
价 格:¥电议型 号:T80011产 地:中国大陆
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T79969Axl-IN-16;化合物 Axl-IN-16Axl-IN-16
Axl-IN-16, a dual Axl/HIF inhibitor, promotes Flammulina velutipes fruiting body formation and suppresses hypoxia-inducible factor activity along with receptor tyrosine kinase expression [1].
价 格:¥电议型 号:T79969产 地:中国大陆
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T79725ARD-1676;化合物 ARD-1676ARD-1676
ARD-1676 is an orally administered androgen receptor (AR) PROTAC degrader that combines an AR ligand with a cereblon ligand. It demonstrates AR-degrading activity both in vitro and in vivo, and effectively inhibits VCaP tumor growth in mouse xenograft models [1].
价 格:¥电议型 号:T79725产 地:中国大陆
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T79670Anti-inflammatory agent 56;化合物 Anti-inflammatory agent 56Anti-inflammatory agent 56
Anti-inflammatory agent 56 (Compound 9), a selective COX-2 inhibitor with an IC50 of 0.54 μM, exhibits anti-oxidant and anti-inflammatory properties by inhibiting oxidative stress-induced cell death and neuroinflammation through the suppression of Keap1, COX-2, and iNOS. It also demonstrates low acute toxicity in mice with an LD50 of 1000 mg/kg [1].
价 格:¥电议型 号:T79670产 地:中国大陆
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T79583AChE-IN-36;化合物 AChE-IN-36AChE-IN-36
AChE-IN-36 (compound A4) is an acetylcholinesterase inhibitor with an IC50 of 0.04 μM, influencing ROS levels and modulating the gene expression of NRF2 [1].
价 格:¥电议型 号:T79583产 地:中国大陆
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T79582Antitumor agent-116;化合物 Antitumor agent-116Antitumor agent-116
Antitumor Agent-116 (Compound 6C) is an anti-tumor agent that exhibits anti-proliferative properties and induces apoptosis. It demonstrates binding affinity for the MELK receptor [1].
价 格:¥电议型 号:T79582产 地:中国大陆
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T79545Antifungal agent 66;化合物 Antifungal agent 66Antifungal agent 66
Antifungal agent 66 (compound 10) exhibits broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia and significant inhibitory effects on the spores of B. cinerea, with an IC50 value of 47.7 μg/mL [1].
价 格:¥电议型 号:T79545产 地:中国大陆
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T79504AMPA receptor modulator-6;化合物 AMPA receptor modulator-6AMPA receptor modulator-6
AMPA receptor modulator-6, an AMPA receptor positive allosteric modulator (PAM), is utilized in the research of neurological diseases [1].
价 格:¥电议型 号:T79504产 地:中国大陆
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T79473Anti-inflammatory agent 46;化合物 Anti-inflammatory agent 46Anti-inflammatory agent 46
Anti-inflammatory agent 46 (compound 7h), exhibiting nitric oxide (NO) inhibitory properties, demonstrates a high affinity for iNOS through low binding energies and effectively reduces swelling in mouse models at a dose of 10 mg/kg [1].
价 格:¥电议型 号:T79473产 地:中国大陆
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T79347Anticancer agent 146;化合物 Anticancer agent 146Anticancer agent 146
Anticancer Agent 146 (Compound 1.19) acts as a necroptosis inducer and demonstrates anti-tumor efficacy in the MDA-MB-231 mouse xenograft model [1].
价 格:¥电议型 号:T79347产 地:中国大陆
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T79334Antiviral agent 36;化合物 Antiviral agent 36Antiviral agent 36
Antiviral agent 36 (compound 27), a potent inhibitor of both dengue (DENV) and Zika (ZIKV) viruses, demonstrates replication inhibition with EC50 values of 100 nM for ZIKV-FLR, 90 nM for ZIKV-HN16, 210 nM for DENV-2, and 120 nM for DENV-3 [1].
价 格:¥电议型 号:T79334产 地:中国大陆
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T793116a,17a-Epoxy-4-Pregnen-3,20-Dione;16,17-环氧黄体酮16a,17a-Epoxy-4-Pregnen-3,20-Dione
16a,17a-Epoxy-4-Pregnen-3,20-Dione is a synthetic progestin, a metabolite of the luteinizing hormone hormone, which acts by binding to the luteinizing hormone receptor. It has been used to study the effects of progesterone on reproductive organs, the effects of the hormone on cell growth and development, and the effects of the hormone on the immune system.
价 格:¥电议型 号:T7931产 地:中国大陆
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T79281Antimycobacterial agent-6;化合物 Antimycobacterial agent-6Antimycobacterial agent-6
Antimycobacterial agent-6 (compound 25) effectively inhibits Mycobacterium tuberculosis, including wild-type and fluoroquinolone-resistant strains, by targeting the Mtb DprE1-C387S mutant. It displays minimal inhibitory concentrations (MIC90) of 0.9 μM for H37Rv and MoxR strains, and 0.5 μM for the DprE1-P116S strain [1].
价 格:¥电议型 号:T79281产 地:中国大陆
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T78970Antitumor agent-96;化合物 Antitumor agent-96Antitumor agent-96
"Antitumor agent-96 (Compound D34) is a potent MRE11 inhibitor that down-regulates the homologous recombination (HR) pathway by binding to and suppressing the endonuclease functions of MRE11, thereby inducing apoptosis in CM cells [1]."
价 格:¥电议型 号:T78970产 地:中国大陆