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T72837Autotaxin-IN-6;化合物 Autotaxin-IN-6Autotaxin-IN-6
Autotaxin-IN-6 (compound 23) is a potent inhibitor of autotaxin (ATX), exhibiting an IC50 of 30 nM, and is capable of attenuating cell migration with potential applications in anticancer research [1].
价 格:¥电议型 号:T72837产 地:中国大陆
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T72523Antitumor agent-46;化合物 Antitumor agent-46Antitumor agent-46
Antitumor agent-46 is an anti-tumor agent. Antitumor agent-46 demonstrates markedly higher antiproliferative activity on MCF-7 cells with an IC 50 value of 2.08 ?M [1] .
价 格:¥电议型 号:T72523产 地:中国大陆
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T72479Anticancer agent 66;化合物 Anticancer agent 66Anticancer agent 66
Anticancer agent 66, a ciprofloxacin analog, functions as an anti-cancer agent by inducing apoptosis and elevating the sub-G1 cell population in MCF-7 cells.
价 格:¥电议型 号:T72479产 地:中国大陆
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T72413Antimicrobial agent-6;化合物 Antimicrobial agent-6Antimicrobial agent-6
Antimicrobial Agent-6, exhibiting a minimum inhibitory concentration (MIC) range of 4-8 μg/mL, is effective against both gram-positive and gram-negative bacteria. Additionally, it demonstrates anti-inflammatory properties.
价 格:¥电议型 号:T72413产 地:中国大陆
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T72304Antibacterial agent 126;化合物 Antibacterial agent 126Antibacterial agent 126
Antibacterial Agent 126 is a potent agent that not only reduces biofilm burden to prevent drug resistance development but also disrupts membrane integrity, resulting in the leakage of intracellular contents. Additionally, it promotes an increase in reactive oxygen species (ROS) and reactive nitrogen species (RNS) production.
价 格:¥电议型 号:T72304产 地:中国大陆
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T72262Antituberculosis agent-6;化合物 Antituberculosis agent-6Antituberculosis agent-6
Antituberculosis agent-6 is a potent antimycobacterial and antifungal compound with significant activity against M. tuberculosis (MIC of 3.49 μM) and A. niger (MIC of 62.50 μM), respectively. It also demonstrates high gastrointestinal (GI) absorption.
价 格:¥电议型 号:T72262产 地:中国大陆
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T72073AKOS037652256;化合物AKOS037652256AKOS037652256
AKOS037652256 can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity such as lysosomal accumulation disorders, muscular dystrophy, common age-related neurodegenerative diseases, oxidative stress or reactive oxygen species (ROS)-related diseases and ageing.
价 格:¥电议型 号:T72073产 地:中国大陆
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T72054SLC26A3-IN-1;化合物SLC26A3-IN-1SLC26A3-IN-1
SLC26A3-IN-1 is an inhibitor of the anion-exchange protein SLC26A3 with an IC50 value of 340 nM.SLC26A3 is a solute carrier (SLC) protein and a member of the SLC26 family, which has a wide range of anionic specificities for chloride, bicarbonate, sulfate, and oxalate.SLC26A3 is downregulated in adenomas (DRA) and is involved in the intestinal absorption of chloride and oxalate and is associated with chloride-losing diarrhea. SLC26A3 is downregulated in adenomas (DRA), is involved in the intestin
价 格:¥电议型 号:T72054产 地:中国大陆
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T71696AM-0466;化合物 AM-0466AM-0466
AM-0466 has a wide range of applications in life science related research.
价 格:¥电议型 号:T71696产 地:中国大陆
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T71639AUH-6-96;化合物 AUH-6-96AUH-6-96
AUH-6-96 is an inhibitor of JAK/STAT signaling, inhibiting both constitutive and interleukin-6-induced STAT3 phosphorylation, selectively affecting cell viability only of cancer cells harboring aberrant JAK/STAT signaling.
价 格:¥电议型 号:T71639产 地:中国大陆
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T71248AM0216;化合物 AM0216AM0216
AM0216 is a novel highly potent inhibitor of NF-κB inducing Kinase (NIK).
价 格:¥电议型 号:T71248产 地:中国大陆
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T71240AS 703026;化合物 AS 703026AS 703026
AS 703026 has been shown to inhibit LPS-induced TNFα production in macrophages/monocytes as well as protect from LPS-induced endotoxin shock. AS 703026 may be useful as an anti-inflammatory therapy for COPD patients.
价 格:¥电议型 号:T71240产 地:中国大陆
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T71209CGS 12066A;化合物 CGS 12066ACGS 12066A
CGS 12066A is a drug which acts as a potent and selective agonist for the 5-HT1B receptor with lower affinity for the three 5-HT? receptor subtypes. It is used for studying the role of the 5-HT1B receptor in various processes including perception of pain and the sleep-wake cycle.
价 格:¥电议型 号:T71209产 地:中国大陆
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T71184ARQ-736;化合物 ARQ-736ARQ-736
ARQ 736 is a potent and selective BRAF inhibitor. ARQ 736 is selectively potent in killing cancer cell lines harboring at least one mutated BRAF allele. BRAF mutations were detected in over 60% of melanomas and may account for a significant proportion of colon cancer patients whose tumors are resistant to anti-EGFR therapy. The B-Raf protein is a key signaling molecule in the mitogen activated protein kinase (MAPK) signaling pathway and has been implicated in the pathogenesis of a variety of ca
价 格:¥电议型 号:T71184产 地:中国大陆
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T71103AZD3676;化合物 AZD3676AZD3676
AZD3676 is a novel dual antagonist of serotonin 5-HT1A and 5-HT1B receptor.
价 格:¥电议型 号:T71103产 地:中国大陆
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T71005CGP-42456A;化合物 CGP-42456ACGP-42456A
CGP-42456A - Benazepril Related Compound A, it is an Impurity. Benazepril is a prodrug which is metabolized by the liver into its active form benazeprilat via cleavage of the drug´s ester group. Benazepril and Benazeprilat inhibit angiotensin-converting enzyme (ACE) in human subjects and animals. Benazeprilat has much greater ACE inhibitory activity than does Benazepril. It is indicated for the treatment of hypertension.
价 格:¥电议型 号:T71005产 地:中国大陆
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T70990ADMA-d6;化合物 ADMA-d6ADMA-d6
NG,NG-dimethyl-L-arginine-d6 (ADMA-d6) (hydrochloride) is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA is an endogenous inhibitor of nitric oxide synthase (NOS). It is formed from arginine by protein arginine methyltransferases (PRMTs) and degraded by dimethylarginine dimethylaminohydrolases (DDAHs) and alanine-glyoxylate aminotransferase 2 (AGXT2). ADMA levels are increased concomitant with an increase in blood pressure in Da
价 格:¥电议型 号:T70990产 地:中国大陆
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T704096alpha-Fluorotestosterone;化合物 6alpha-Fluorotestosterone6alpha-Fluorotestosterone
6alpha-Fluorotestosterone is a synthetic nonaromatizable androgen analog of testosterone. It binds to and activates specific nuclear receptors inhibits and is equipotent to testosterone.
价 格:¥电议型 号:T70409产 地:中国大陆
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T70265AL-6556;化合物 AL-6556AL-6556
AL-6556 is a prostaglandin DP receptor agonist.
价 格:¥电议型 号:T70265产 地:中国大陆
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T70194AM92016;化合物 AM92016AM92016
AM92016 is a specific blocker of the time dependent delayed rectifier potassium current. AM92016 does not show any β-adrenoceptor blocking activity.
价 格:¥电议型 号:T70194产 地:中国大陆