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  • T78963Antileishmanial agent-16；化合物 Antileishmanial agent-16Antileishmanial agent-16

    Antileishmanial agent-16 (compound 14c), an anti-Leishmania agent, exhibits potent activity against Leishmania major promastigotes (IC50 = 0.59 ?M) and amastigotes (IC50 = 0.81 ?M), while maintaining a favorable safety profile in mammalian cells (VERO cells) [1].

    价 格：￥电议型 号：T78963产 地：中国大陆

  • T78958Anticancer agent 106；化合物 Anticancer agent 106Anticancer agent 106

    Compound 106 (compound 10ic) induces apoptosis in B16-F10 melanoma cells and potently inhibits metastatic nodules in mouse models of lung metastatic melanoma, suggesting its utility in the study of cancer, particularly lung metastatic melanoma [1].

    价 格：￥电议型 号：T78958产 地：中国大陆

  • T78952Antimalarial agent 26；化合物 Antimalarial agent 26Antimalarial agent 26

    Antimalarial agent 26, a derivative of 1,4-naphthoquinones, demonstrates antimalarial properties through oral administration. It exhibits cytotoxic effects on P. falciparum while maintaining selectivity against mammalian cell lines and effectively inhibits P. berghei-induced parasitemia in vivo [1].

    价 格：￥电议型 号：T78952产 地：中国大陆

  • T78929Anticancer agent 126；化合物 Anticancer agent 126Anticancer agent 126

    Anticancer agent 126 (compound 12), a WDR5 inhibitor, exhibits anticancer properties by disrupting the WDR5-MYC interaction in cells, subsequently reducing MYC target gene expression [1].

    价 格：￥电议型 号：T78929产 地：中国大陆

  • T78915AD186；化合物 AD186AD186

    AD186, a potent and selective S1R agonist, exhibits dissociation constants (Kis) of 2.7 nM for S1R and 27 nM for S2R. Notably, AD186 completely reverses the antiallodynic effect of BD-1063 [1].

    价 格：￥电议型 号：T78915产 地：中国大陆

  • T78897Antibacterial agent 156；化合物 Antibacterial agent 156Antibacterial agent 156

    Antibacterial Agent 156 (Compound 57), a bactericidal that selectively targets C. difficile cell-wall synthesis, demonstrates potent activity with minimal inhibitory concentrations of 0.5 μg/mL for MIMIC50 (101 strains) and 1 μg/mL for MIC90 (101 strains) [1].

    价 格：￥电议型 号：T78897产 地：中国大陆

  • T78833AJH-836；化合物 AJH-836AJH-836

    AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation of Munc13-1 from the cytoplasm to the plasma membrane. It is utilized in neurodegenerative disease research [1].

    价 格：￥电议型 号：T78833产 地：中国大陆

  • T78764Anticancer agent 136；化合物 Anticancer agent 136Anticancer agent 136

    Anticancer agent 136 (compound 22), a C17-triazole analogue of Geldanamycin (GDM), exhibits an IC50 value of 3.38 μM against human dermal fibroblasts (HDF) and binds to Heat shock protein 90 (Hsp90) with a dissociation constant (Kd) of 3.86 μM, demonstrating its apoptosis-inducing capabilities [1].

    价 格：￥电议型 号：T78764产 地：中国大陆

  • T78710AMX12006；化合物 AMX12006AMX12006

    AMX12006, a potent and selective EP4 antagonist, exhibits cytotoxic and antitumor activity, demonstrating oral activity with an IC50 of 4.3 nM [1].

    价 格：￥电议型 号：T78710产 地：中国大陆

  • T78698Aβ-IN-6；化合物 Aβ-IN-6Aβ-IN-6

    Aβ-IN-6 is an orally active compound exhibiting anti-inflammatory, antioxidant, and anti-oligomeric activities, with significant implications for Alzheimer´s disease (AD) research [1]. It effectively reduces the release of pro-inflammatory cytokines from microglia cells, promotes Nrf2 nuclear translocation, and impedes the formation of Aβ oligomers. Furthermore, Aβ-IN-6 demonstrates a stable neuroprotective effect by modulating redox-sensitive signaling pathways in an in vivo oxidative str

    价 格：￥电议型 号：T78698产 地：中国大陆

  • T78644A-77636；化合物 A-77636A-77636

    A-77636 is a potent, selective, and long-acting oral dopamine D1 receptor agonist with an effective concentration (EC50) of 1.1 nM and a corresponding pEC50 value of 8.13. It demonstrates the highest affinity for the dopamine D1 receptor with a dissociation constant (Ki) of 39.8 nM and a pKi of 7.40 ± 0.09. Notably, A-77636 exhibits antiparkinsonian activity [1].

    价 格：￥电议型 号：T78644产 地：中国大陆

  • T78604SLC26A3-IN-3；化合物 SLC26A3-IN-3SLC26A3-IN-3

    SLC26A3-IN-3 (compound 4az), a potent SLC26A3 inhibitor with an IC50 of 40 nM, is utilized for constipation and cystic fibrosis research [1].

    价 格：￥电议型 号：T78604产 地：中国大陆

  • T78285Sofituzumab；化合物 SofituzumabMMUC 1206A；MMUC 1206A

    Sofituzumab (MMUC 1206A) is a humanized monoclonal antibody targeting the MUC16 antigen, specifically the recombinant V-kappa immunoglobulin variant [1].

    价 格：￥电议型 号：T78285产 地：中国大陆

  • T77754ALK-IN-26；化合物 ALK-IN-26ALK-IN-26

    ALK-IN-26 is an ALK inhibitor with potential anticancer activity.ALK-IN-26 shows antiproliferative activity against glioblastoma.ALK-IN-26 induces apoptosis, autophagy and necrosis.

    价 格：￥电议型 号：T77754产 地：中国大陆

  • T77520AOH1996；化合物AOH1996AOH1996

    AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC).AOH1996 interferes with the interaction of PCNA with its binding proteins, leading to DNA replication stress and apoptosis.AOH1996 causes proteasome-dependent rpb1 degradation and lethal DNA damage by stabilizing the interaction between PCNA and RNA polymerase II.AOH1996 acts synergistically with DNA damaging agents to inhibit tumor ce

    价 格：￥电议型 号：T77520产 地：中国大陆

  • T76766Mirvetuximab；米妥昔单抗M9346A；M9346A

    Mirvetuximab (M9346A) is a novel folate receptor α (FRα) monoclonal antibody targeting anti-FOLR1 (folate receptor 1). Mirvetuximab soravtansine is often conjugated with platinum compounds or other compounds to form antibody-drug conjugates for the treatment of ovarian cancer and other FRα-positive cancers.

    价 格：￥电议型 号：T76766产 地：中国大陆

  • T7673ATH686；化合物ATH 686ATH 686；ATH 686

    ATH686 is an potent and selective Inhibitor of FLT3.

    价 格：￥电议型 号：T7673产 地：中国大陆

  • T76228ASP5286；化合物 ASP5286ASP5286

    ASP5286 is a novel non-immunosuppressive cyclophilin inhibitor for the research of HCV .

    价 格：￥电议型 号：T76228产 地：中国大陆

  • T75833HNGF6A TFA；化合物 HNGF6A TFAHNGF6A TFA

    HNGF6A TFA, a humanin analogue, enhances glucose-stimulated insulin secretion and glucose metabolism, offering potential for diabetes research. It also inhibits ROS (Reactive Oxygen Species) production under oxidative stress and may prevent endothelial dysfunction and atherosclerosis in vivo [1] [2].

    价 格：￥电议型 号：T75833产 地：中国大陆

  • T7582tafamidis meglumine；他发米帝司甲葡胺Fx-1006A；Fx-1006A|||他发米帝司甲葡胺

    Tafamidis meglumine (Fx-1006A) is a Potent and Selective Transthyretin Kinetic Stabilizer That Inhibits the Amyloid Cascade

    价 格：￥电议型 号：T7582产 地：中国大陆

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