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  • T69813AZD-6126；化合物 AZD-6126AZD-6126

    AZD6126, also known as ANG-453, a water-soluble phosphate prodrug of N-acetylcolchinol with potential antiangiogenesis and antineoplastic activities. AZD-6126 is an angiogenesis inhibitor and tubulin inhibitor potentially for the treatment of solid tumours. AZD6126 is converted in vivo into N-acetylcolchinol. N-acetylcolchinol binds to and destabilizes the tubulin cytoskeleton of endothelial cells in tumor blood vessels, which may result in tumor endothelial cel apoptosis, the selective occlusio

    价 格：￥电议型 号：T69813产 地：中国大陆

  • T69811AGI25696；化合物 AGI25696AGI25696

    AGI-25696 is a MATA2 inhibitor that are useful as therapeutic agents for treating malignancies. AGI-25696 showed in vivo activity in MTAP null tumors. Note: The correct structure of AGI-25696 is CAS#2201065-84-9. Many vendors mistakenly listed CAS#2201066-35-3 as its AGI25696. J. Med. Chem. 2021, 64, 8, 4430–4449 published AGI25696 structure (it is CAS#2201065-84-9).

    价 格：￥电议型 号：T69811产 地：中国大陆

  • T69805AU-006；化合物 AU-006AU-006

    AU-006 is an anti-ulcer drug which is effective in the treatment of gastric ulcers by inhibiting gastric acid secretion.

    价 格：￥电议型 号：T69805产 地：中国大陆

  • T69748AG-12286；化合物 AG-12286AG-12286

    AG-12286 is a pan-CDK inhibitor. AG-012986 may be useful in the treatment of tumors by inhibiting p38 MAPK phosphorylation. Note: many vendors confused the structure of AG-12286 (CAT#573461, CAS# 223784-75-6) with AG-012986 (CAT#406184, CAS# is 486414-35-1).

    价 格：￥电议型 号：T69748产 地：中国大陆

  • T69606ARN23746；化合物 ARN23746ARN23746

    ARN23746 is a NKCC1 Inhibitor for the Treatment of Core Symptoms in Down Syndrome.

    价 格：￥电议型 号：T69606产 地：中国大陆

  • T69453APC-0576；化合物 APC-0576APC-0576

    APC-0576 is an (S,S)-isomer which inhibits NF-kappaB-dependent gene activation. APC-0576 may prevent pro-inflammatory cytokine-induced chemokine production in human endothelial cells.

    价 格：￥电议型 号：T69453产 地：中国大陆

  • T69329AY 23626；化合物 AY 23626AY 23626

    AY 23626 is a Prostaglandin E2 agonist.

    价 格：￥电议型 号：T69329产 地：中国大陆

  • T69328A-320436；化合物 A-320436A-320436

    A-320436 is an H3 receptor antagonist that may affect cognition.

    价 格：￥电议型 号：T69328产 地：中国大陆

  • T69230AZD-1236；化合物 AZD-1236AZD-1236

    AZD1236 is a potent and reversible inhibitor of human MMP-9 and MMP-12 (IC50 = 4.5 and 6.1nM, respectively), with >10-fold selectivity to MMP-2 and MMP-13 and >350-fold selectivity to other members of the enzyme family. AZD1236 activity is approximately 20 to 50-fold lower at the rat, mouse, and guinea pig orthologues. In acute models of lung injury, AZD1236 inhibited the haemorrhage and inflammation induced by instillation of human MMP-12 into rat lungs by ~80% at 0.81mg/kg, and also abolished

    价 格：￥电议型 号：T69230产 地：中国大陆

  • T69196AG-012986；化合物 AG-012986AG-012986

    AG-012986 is a multitargeted cyclin-dependent kinase (CDK) inhibitor active against CDK1, CDK2, CDK4/6, CDK5, and CDK9, with selectivity over a diverse panel of non-CDK kinases. AG-012986 showed antiproliferative activities in vitro with IC(50)s of <100 nmol/L in 14 of 18 tumor cell lines. In vivo, significant antitumor efficacy induced by AG-012986 was seen (tumor growth inhibition, >83.1%) in 10 of 11 human xenograft tumor models. AG-012986 also showed dose-dependent retinoblastoma Ser(795) hy

    价 格：￥电议型 号：T69196产 地：中国大陆

  • T69047ML-236A；化合物 ML-236AML-236A

    ML-236A is an inhibitor of cholesterogenesis.

    价 格：￥电议型 号：T69047产 地：中国大陆

  • T69046AK-106；化合物 AK-106AK-106

    AK-106, also known as AK106-001616, is a selective inhibitor of cytosolic phospholipase A2 (cPLA2) inhibitor. AK-106 has been shown to have analgesic activites similar to non-steroidal anti-inflammatory drugs (NSAIDs).

    价 格：￥电议型 号：T69046产 地：中国大陆

  • T68967AFG206；化合物 AFG206AFG-206.|||AFG-206|||AFG206|||AFG 206|||AFG 206；AFG-206.|||AFG-206|||AFG206|||AFG 2

    AFG206 is the novel first-generation type II" FLT3 inhibitor."

    价 格：￥电议型 号：T68967产 地：中国大陆

  • T68625AX-7396；化合物 AX-7396AX-7396

    AX-7396 is a protein kinase inhibitor with anti-cytomegaloviral properties.

    价 格：￥电议型 号：T68625产 地：中国大陆

  • T68576AGN-204396；化合物 AGN-204396AGN-204396

    AGN-204396 is an antagonist that selectively blocks the activity of prostamides (prostaglandin-ethanolamides).

    价 格：￥电议型 号：T68576产 地：中国大陆

  • T68550SKF89976A HCl；化合物 SKF89976A HClSKF89976A HCl

    SKF89976A is a potent GABA uptake inhibitor, which is selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). SKF89976A inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). It is able to pass the blood-brain barrier after systemic administration and is active in vivo.

    价 格：￥电议型 号：T68550产 地：中国大陆

  • T68455AP23846；化合物 AP23846AP-23846；AP-23846

    AP23846 is a novel and potent Src family kinase inhibitor that reduces vascular endothelial growth factor and interleukin-8 expression and abrogates downstream angiogenic processes in human solid tumor cell lines.

    价 格：￥电议型 号：T68455产 地：中国大陆

  • T68281AZD-1386；化合物 AZD-1386AZD-1386

    AZD1386 is an orally available antagonist of the transient receptor potential channel TRPV1. Note: Structure of this product was from NIH/NCATS web page: https://drugs.ncats.io/drug/210323T9CP and drugbank web page: https://go.drugbank.com/drugs/DB15333.

    价 格：￥电议型 号：T68281产 地：中国大陆

  • T68271AZD1386；化合物 AZD1386AZD1386

    AZD1386 is a TRPV1 antagonist. AZD1386 acts as a competitive antagonist at the channel´s capsaicin binding site.

    价 格：￥电议型 号：T68271产 地：中国大陆

  • T68262AEG40826；化合物 AEG40826AEG40826

    AEG40826 (HGS1029) is the hydrochloride salt of a small-molecule inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins with potential antineoplastic activity. IAP inhibitor HGS1029 selectively inhibits the biological activity of IAP proteins, which may restore apoptotic signaling pathways; this agent may work synergistically with cytotoxic drugs to overcome tumor cell resistance to apoptosis. IAPs are overexpressed by many cancer cell types, suppressing apoptosis by binding and inhib

    价 格：￥电议型 号：T68262产 地：中国大陆

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