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  • T74383TLR4-IN-C34-C2-amide-C6-OH；化合物 TLR4-IN-C34-C2-amide-C6-OHTLR4-IN-C34-C2-amide-C6-OH

    TLR4-IN-C34-C2-amide-C6-OH, a chemical compound, serves as a linker encompassing the TLR4 inhibitor TLR4-IN-C34. This inhibitor is known to target TLR4 in enterocytes and macrophages, effectively reducing systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis [1].

    价 格：￥电议型 号：T74383产 地：中国大陆

  • T74224UNC6349 (Ket2)；化合物 UNC6349 (Ket2)UNC6349 (Ket2)

    UNC6349 (Ket2), a ligand containing diethyllysine (Ket2), effectively binds to wild-type CBX5 with a dissociation constant (K D) of 3.2 μM [1].

    价 格：￥电议型 号：T74224产 地：中国大陆

  • T74223UNC6864 (Kei)；化合物 UNC6864 (Kei)UNC6864 (Kei)

    UNC6864, an ethylisopropyllysine-containing ligand, exhibits binding affinity to wild-type CBX5, demonstrating a dissociation constant (K D) of 3.3 μM.

    价 格：￥电议型 号：T74223产 地：中国大陆

  • T73043HDAC6-IN-15；化合物 HDAC6-IN-15HDAC6-IN-15

    HDAC6-IN-15, a selective histone deacetylase 6 (HDAC6) inhibitor, exhibits potent inhibitory activity with an IC50 value of 38.2 nM, making it valuable for research in cancer and neurodegenerative diseases.

    价 格：￥电议型 号：T73043产 地：中国大陆

  • T73031HDAC6-IN-14；化合物 HDAC6-IN-14HDAC6-IN-14

    HDAC6-IN-14, an inhibitor of HDAC6 (HDAC), exhibits high selectivity with an IC50 value of 42 nM, demonstrating over 100-fold selectivity compared to HDAC1, HDAC2, HDAC3, and HDAC4.

    价 格：￥电议型 号：T73031产 地：中国大陆

  • T72819UNC6212 (Kme2)；化合物 UNC6212 (Kme2)UNC6212 (Kme2)

    UNC6212 (Kme2), a dimethyllysine (Kme2)-containing ligand, has a K D for CBX5 of 5.7 μM [1] .

    价 格：￥电议型 号：T72819产 地：中国大陆

  • T71580EBV activator C60；化合物 EBV activator C60EBV activator C60

    EBV activator C60 is an EBV activator, and a well-performing EBV lytic cycle inducer.

    价 格：￥电议型 号：T71580产 地：中国大陆

  • T70534NSC654259；化合物 NSC654259NSC654259

    NSC654259 is a BPU derivative and is an effective inhibitor of in vitro tubulin polymerization

    价 格：￥电议型 号：T70534产 地：中国大陆

  • T69753HDAC6 degrader 9c；HDAC6 降解剂9cHDAC6 degrader 9c

    HDAC6 degrader 9c is a small molecule histone deacetylase 6 (HDAC6) degrader that can be used to study cancer or other diseases.

    价 格：￥电议型 号：T69753产 地：中国大陆

  • T69580SGC6870；化合物 SGC6870SGC6870

    SGC6870 is a novel potent, selective, and cell-active inhibitor of PRMT6 with IC50 of 77 ± 6 nM, being selective over all other PRMTs and 23 methyltransferases.

    价 格：￥电议型 号：T69580产 地：中国大陆

  • T69441NSC66098；化合物 NSC66098NSC66098

    NSC66098 is a novel potent inhibitor of Huntington´s disease (HD) pathogenesis via targeting CAG repeats RNA and Poly Q protein.

    价 格：￥电议型 号：T69441产 地：中国大陆

  • T69316DA 3003-2；化合物 DA-3003-2NSC663285；NSC663285

    DA 3003-2, a selectively potent Cdc25 inhibitor, exhibits antiproliferative activity and holds potential for prostate cancer research. It induces cell cycle arrest at the G2/M phase and increases the expression of P-tyr 15 Cdc2.

    价 格：￥电议型 号：T69316产 地：中国大陆

  • T677846-fluorinated-aristeromycin2c；化合物 6-fluorinated-aristeromycin2c6-fluorinated-aristeromycin2c

    6-fluorinated inated-aristeromycin2c showed antiviral activity against heat virus, Zika virus and Sars coronavirus.

    价 格：￥电议型 号：T67784产 地：中国大陆

  • T6611NSC697923；化合物NSC6979232-[(4-methylphenyl)sulfonyl]-5-nitrofuran；2-[(4-methylphenyl)sulfonyl]-5-nitro

    NSC-697923 (2-[(4-methylphenyl)sulfonyl]-5-nitrofuran), a potent inhibitor of UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13), exhibits its role in inducing cell death in neuroblastoma (NB) cells through two distinct mechanisms. In p53 wild-type NB cells, NSC-697923 promotes the nuclear importation of p53, thereby triggering cell death. Meanwhile, in p53 mutant NB cells, NSC-697923 activates the JNK-mediated apoptotic pathway, leading to cell death. Additionally, NSC-697923 inhibits DNA damage

    价 格：￥电议型 号：T6611产 地：中国大陆

  • T63531HDAC6/HSP90-IN-1；化合物 HDAC6/HSP90-IN-1HDAC6/HSP90-IN-1

    HDAC6/HSP90-IN-1 is a potent and selective dual inhibitor of HDAC6 (IC50: 4.3 nM) and HSP90 (IC50: 46.8 nM).HDAC6/HSP90-IN-1 downregulates PD-L1 expression in INF-γ-treated H1975 lung cancer cells.HDAC6/HSP90-IN-1 exhibits tumor growth inhibition in H1975 xenograft mice.HDAC6/HSP90-IN-1 is a potent and selective dual inhibitor of HDAC6 (IC50: 4.3 nM) and HSP90 (IC50: 46.8 nM). 1 exhibited tumor growth inhibition in H1975 xenograft mice.

    价 格：￥电议型 号：T63531产 地：中国大陆

  • T63472HDAC6-IN-4；化合物 HDAC6-IN-4HDAC6-IN-4

    HDAC6-IN-4 (C10) is an orally active, highly selective, potent and non-significantly toxic HDAC6 inhibitor (IC50: 23 nM). HDAC6-IN-4 induces apoptosis and exhibits potent anti-tumor effects.

    价 格：￥电议型 号：T63472产 地：中国大陆

  • T6327Tubacin；HDAC6 抑制剂Tubacin

    Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.

    价 格：￥电议型 号：T6327产 地：中国大陆

  • T63247HDAC6-IN-12；化合物 HDAC6-IN-12HDAC6-IN-12

    HDAC6-IN-12 is a potent inhibitor of HDAC6 that binds in the DNA chain, causing DNA damage and exhibiting anticancer effects that can be used in cancer research.

    价 格：￥电议型 号：T63247产 地：中国大陆

  • T62272TRPC6-IN-3；化合物 TRPC6-IN-3TRPC6-IN-3

    TRPC6-IN-3 (compound 17) is an orally active inhibitor of the transient receptor potential C6 ion channel (TRPC6), which regulates intracellular calcium concentration and also regulates cation fluxes including calcium and sodium ions to modulate membrane potential.

    价 格：￥电议型 号：T62272产 地：中国大陆

  • T62201TRPC6-IN-2；化合物 TRPC6-IN-2TRPC6-IN-2

    TRPC6-IN-2 is a TRPC protein inhibitor, specifically inhibiting TRPC6 protein.

    价 格：￥电议型 号：T62201产 地：中国大陆

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