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  • T62046HDAC6-IN-5；化合物 HDAC6-IN-5HDAC6-IN-5

    HDAC6-IN-5 (compound 11b) is a potent and BBB-penetrated inhibitor of HDAC6 (IC50= 0.025 μM). HDAC6-IN-5 inhibits Aβ 1-42 self-aggregation and AChE, with IC 50s of 3.0 and 0.72 μM. HDAC6-IN-5 can enhance neurite outgrowth without significant neurotoxicity.

    价 格：￥电议型 号：T62046产 地：中国大陆

  • T61888mTOR/HDAC6-IN-1；化合物 mTOR/HDAC6-IN-1mTOR/HDAC6-IN-1

    mTOR/HDAC6-IN-1 is an effective dual inhibitor of histone deacetylase (HDAC6) and mammalian rapamycin (mTOR). The IC50 values for HDAC6 and mTOR are 56 nM and 133.7 nM respectively. MTOR/HDAC6-IN-1 can significantly induce autophagy and apoptosis and inhibit migration. MTOR/HDAC6-IN-1 has potential in the study of triple negative breast cancer (TNBC).

    价 格：￥电议型 号：T61888产 地：中国大陆

  • T61884C6 Ceramide；C6神经酰胺N-hexanoylsphingosine|||N-(hexanoyl)sphing-4-enine；N-hexanoylsphingosine|||N-(hexa

    C6 Ceramide (N-hexanoylsphingosine) is an activator of the ceramide pathway that arrests cells in the G0/G1 phase by activating ERK. It can act in a variety of cancer cell lines.

    价 格：￥电议型 号：T61884产 地：中国大陆

  • T61792HDAC6-IN-10；化合物 HDAC6-IN-10HDAC6-IN-10

    HDAC6-IN-10 is a potent and specific HDAC6 inhibitor, exhibiting an IC50 value of 0.73 nM. It demonstrates remarkable selectivity towards HDAC6, with a selectivity range of 144 to 10,941-fold over other HDAC isoforms. Furthermore, HDAC6-IN-10 exhibits notable anti-proliferative effects on multiple myeloma cells [1].

    价 格：￥电议型 号：T61792产 地：中国大陆

  • T61727HDAC6/8/BRPF1-IN-1；化合物 HDAC6/8/BRPF1-IN-1HDAC6/8/BRPF1-IN-1

    HDAC6/8/BRPF1-IN-1 is a dual inhibitor that targets HDAC6, HDAC8, and the bromodomain and PHD finger containing protein 1 (BRPF1). It exhibits inhibitory activity against HDAC1, HDAC6, and HDAC8 with IC50 values of 797 nM, 344 nM, and 908 nM, respectively. In addition, it inhibits BRPF1 with a Kd value of 175.2 nM. This compound is utilized in cancer research [1].

    价 格：￥电议型 号：T61727产 地：中国大陆

  • T61474HDAC6-IN-13；化合物 HDAC6-IN-13HDAC6-IN-13

    HDAC6-IN-13 (Compound 35m) is a potent and highly selective orally active inhibitor of HDAC6, with an IC50 of 0.019 μM. It also demonstrates inhibitory activity against HDAC1, HDAC2, and HDAC3, with IC50 values of 1.53 μM, 2.06 μM, and 1.03 μM, respectively. HDAC6-IN-13 exhibits substantial blood-brain barrier permeability and displays anti-inflammatory properties [1].

    价 格：￥电议型 号：T61474产 地：中国大陆

  • T61315HDAC6/HSP90-IN-2；化合物 HDAC6/HSP90-IN-2HDAC6/HSP90-IN-2

    HDAC6/HSP90-IN-2 (compound 6e) is a dual inhibitor targeting HDAC6 and Hsp90, exhibiting IC50 values of 105.7 nM and 61 nM, respectively. It is primarily utilized in cancer research [1].

    价 格：￥电议型 号：T61315产 地：中国大陆

  • T61139HDAC6-IN-3；化合物 HDAC6-IN-3HDAC6-IN-3

    HDAC6-IN-3 (Compound 14) is a potent anti-prostate cancer agent that acts as an orally active inhibitor of HDAC6. It has IC50 values ranging from 0.02-1.54 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10. Additionally, HDAC6-IN-3 also demonstrates effective inhibition of MAO-A (IC50 = 0.79 μM) and LSD1 [1].

    价 格：￥电议型 号：T61139产 地：中国大陆

  • T61044HDAC6-IN-11；化合物 HDAC6-IN-11HDAC6-IN-11

    HDAC6-IN-11 (Compound 9) has anti-proliferative activities against cancer cells. HDAC6-IN-11 is a selective inhibitor of HDAC6 with the IC50 value of 20.7 nM. The selectivity of HDAC6-IN-11 is more than 300-fold over HDAC other isoforms [1].

    价 格：￥电议型 号：T61044产 地：中国大陆

  • T60954HDAC6-IN-6；化合物 HDAC6-IN-6HDAC6-IN-6

    HDAC6-IN-6 (compound 6a) is a potent inhibitor of HDAC6 that can penetrate BBB with an IC50 value of 0.025 μM. HDAC6-IN-6 has potent inhibitory activity against AChE and Aβ 1-42 self-aggregation with IC50 values of 0.72 and 3.0 μM. HDAC6-IN-6 can enhance the outgrowth of neurite without significant neurotoxicity [1].

    价 格：￥电议型 号：T60954产 地：中国大陆

  • T60856HDAC6-IN-9；化合物 HDAC6-IN-9HDAC6-IN-9

    HDAC6-IN-9 (compound 12c) is a potent and selective inhibitor of HDAC6 with anti-proliferative activities. The IC 50 values of HDAC6-IN-9 for HDAC6, HDAC1,HDAC3, HDAC8, and HDAC10 is 4.2, 11.8, 15.2, 139.6, and 21.3 nM, respectively [1].

    价 格：￥电议型 号：T60856产 地：中国大陆

  • T5S1131Ganoderic acid C6灵芝酸C6灵芝酸C6

    1. Ganoderic acid C6 has antinociceptive activity.

    价 格：￥电议型 号：T5S1131产 地：中国大陆

  • T5854AM580；化合物AM580NSC608001|||CD336|||Ro 40-6055；NSC608001|||CD336|||Ro 40-6055

    AM580 (CD336) is a retinoic acid receptor agonist that is selective for RARα( IC50 : 8 nM )

    价 格：￥电议型 号：T5854产 地：中国大陆

  • T5538DC661；化合物DC661DC661

    DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity.

    价 格：￥电议型 号：T5538产 地：中国大陆

  • T41141Fullerene-C60Fullerene-C60Fullerene-C60

    Fullerene-C60, a carbon nanocompound, is considered a potential agent for photodynamic therapy owing to its distinctive physicochemical properties. It investigates the dynamics of intramolecular electron and energy transfer.

    价 格：￥电议型 号：T41141产 地：中国大陆

  • T40858NH2-PEG2-C6-Cl；化合物NH2-PEG2-C6-ClNH2-PEG2-C6-Cl；NH2-PEG2-C6-Cl

    NH2-PEG2-C6-Cl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T40858产 地：中国大陆

  • T40201Azido-PEG2-C6-Cl；Azido-PEG2-C6-ClAzido-PEG2-C6-Cl；Azido-PEG2-C6-Cl

    Azido-PEG2-C6-Cl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T40201产 地：中国大陆

  • T40146Sec61-IN-1；化合物Sec61-IN-1Sec61-IN-1；Sec61-IN-1

    Sec61-IN-1 is a potent sec61 inhibitor.

    价 格：￥电议型 号：T40146产 地：中国大陆

  • T40031Thalidomide-O-C6-NH2 hydrochloride；萨力多胺-O-C6-氨基盐酸盐4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)i

    Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) is a synthesized E3 ligase ligand-linker conjugate.

    价 格：￥电议型 号：T40031产 地：中国大陆

  • T40027(S,R,S)-AHPC-C6-NH2；化合物 T40027(S,R,S)-AHPC-C6-NH2

    (S,R,S)-AHPC-C6-NH2 is a useful organic compound for research related to life sciences. The catalog number is T40027 and the CAS number is 2306389-03-5.

    价 格：￥电议型 号：T40027产 地：中国大陆

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