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T37428TRPC6-PAM-C20；化合物TRPC6-PAM-C20TRPC6-PAM-C20|||3-(6,7-Dimethoxy-3,3-dimethyl-3,4-dihydro-isoquinolin-
TRPC6-PAM-C20 is a selective TRPC6 positive allosteric modulator. TRPC6-PAM-C20 induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 with an EC50 of 2.37 μM. TRPC6-PAM-C20 enhances OAG-induced platelet aggregation.
价 格：￥电议型 号：T37428产 地：中国大陆
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T36660Olsalazine-13C6；Olsalazine-13C6Olsalazine-13C6；Olsalazine-13C6
Olsalazine-13C6is intended for use as an internal standard for the quantification of olsalazine by GC- or LC-MS. Olsalazine is an orally bioavailable prodrug form of the anti-inflammatory agent 5-aminosalicylic acid that is cleaved by bacterial azo reductases in the gut to generate active 5-ASA.1
价 格：￥电议型 号：T36660产 地：中国大陆
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T36625LSD1/HDAC6-IN-1；LSD1/HDAC6-IN-1LSD1/HDAC6-IN-1；LSD1/HDAC6-IN-1
LSD1/HDAC6-IN-1 is an orally active compound that functions as a dual inhibitor, targeting lysine specific demethylase 1 (LSD1) and histone deacetylase 6 (HDAC6). This compound demonstrates promising anti-tumor activity and is particularly valuable for research focused on multiple myeloma (MM) [1].
价 格：￥电议型 号：T36625产 地：中国大陆
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T36321C6 Urea CeramideC6 Urea CeramideC6 Urea Ceramide|||C-6 Urea Ceramide
C6 urea ceramide is an inhibitor of neutral ceramidase.1 It increases total ceramide levels in wild-type mouse embryonic fibroblasts (MEFs) and in HT-29 colon cancer cells but not in MEFs lacking neutral ceramidase. It inhibits proliferation of, and induces apoptosis and autophagy in HT-29, but not non-cancerous RIE-1, cells when used at concentrations of 5 and 10 μM. C6 urea ceramide decreases total β-catenin, increases phosphorylated β-catenin, and induces colocalization of β-catenin with the
价 格：￥电议型 号：T36321产 地：中国大陆
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T36320C6 L-threo Ceramide (d18:1/6:0)；C6 L-threo Ceramide (d18:1/6:0)C6 L-threo Ceramide (d18:1/6:0)；C6 L-
C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 L-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 L-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 L-threo Ceramide enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells when used at a concentration of 10 μM.
价 格：￥电议型 号：T36320产 地：中国大陆
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T36319C6 L-erythro Ceramide (d18:1/6:0)；C6 L-erythro Ceramide (d18:1/6:0)C6 L-erythro Ceramide (d18:1/6:0)
C6 L-erythro Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is metabolized by ceramide glucosyltransferase to form C6 L-erythro glucosylceramide. C6 L-erythro Ceramide is cytotoxic to U937 cells (IC50 = 18 μM).
价 格：￥电议型 号：T36319产 地：中国大陆
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T36274VH 101 phenol-alkylC6-amine；VH 101 phenol-alkylC6-amineVH 101 phenol-alkylC6-amine；VH 101 phenol-alk
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC6 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
价 格：￥电议型 号：T36274产 地：中国大陆
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T36270(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride；VH 032 phenol-alkylC6-amineVH 032 phenol-alkylC6-a
Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 phenol - linker 2 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
价 格：￥电议型 号：T36270产 地：中国大陆
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T36059Dichlorphenamide-13C6；Dichlorphenamide-13C6Dichlorphenamide-13C6；Dichlorphenamide-13C6
Dichlorphenamide-13C6is intended for use as an internal standard for the quantification of dichlorphenamide by GC- or LC-MS. Dichlorphenamide is a sulfonamide and an orally bioavailable carbonic anhydrase (CA) inhibitor (Kis = 1.20, 38, 50, and 50 nM for the human CA isoforms CAI, CAII, CAIX, and CAXII, respectively).1It lowers intraocular pressure in rabbits when 50 μl of a 10% solution is applied topically to the eye.2Dichlorphenamide rescues the potassium deficiency and prevents insulin-induc
价 格：￥电议型 号：T36059产 地：中国大陆
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T36055Nitisinone-13C6；Nitisinone-13C6Nitisinone-13C6；Nitisinone-13C6
Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (F
价 格：￥电议型 号：T36055产 地：中国大陆
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T35915Erlotinib-13C6；Erlotinib-13C6Erlotinib-13C6；Erlotinib-13C6
Erlotinib-13C6 (CP-358774-13C6) is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1].
价 格：￥电议型 号：T35915产 地：中国大陆
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T356832-deoxy-D-Glucose-13C6；2-deoxy-D-Glucose-13C62-deoxy-D-Glucose-13C6；2-deoxy-D-Glucose-13C6
2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate.32-deoxy-D-Glucose (16 mM) induces apoptosis in SK-BR-3 cells, as well as inhibits the growth of 143B oste
价 格：￥电议型 号：T35683产 地：中国大陆
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T35618D-Fructose-13C6D-果糖 13C6D-果糖 13C6
D-Fructose-13C6 can be used as an internal standard for the quantification of D-fructose by GC- or LC-MS.
价 格：￥电议型 号：T35618产 地：中国大陆
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T35362NSC622608；化合物NSC622608NSC622608
NSC622608 is a small-molecule ligand for V-domain Ig suppressor of T-cell activation (VISTA) which is an immune checkpoint that affects the ability of T-cells to attack tumors.
价 格：￥电议型 号：T35362产 地：中国大陆
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T34996Ukrain；化合物 T34996NSC631570|||NSC 631570|||NSC-631570；NSC631570|||NSC 631570|||NSC-631570
Ukrain, also known as NSC-631570, is claimed to be a semisynthetic compound of thiophosphoric acid (triaziridide) and the alkaloid chelidonine derived from the common weed, Chelidonium majus (greater celandine), which grows primarily in Europe and Asia.
价 格：￥电议型 号：T34996产 地：中国大陆
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T34872Tiadenol；化合物 T34872LL 1558|||NSC66316|||LL-1558|||LL1558 NSC 66316|||NSC-66316；LL 1558|||NSC66316|||
Tiadenol is a Hypolipidemic Agent.
价 格：￥电议型 号：T34872产 地：中国大陆
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T34613Seneciphylline, hydrochloride；化合物 T34613NCI C61165|||NSC-30622|||NCIC61165|||NCI-C61165|||NSC 30622；
Seneciphylline, hydrochloride is a bioactive chemical.
价 格：￥电议型 号：T34613产 地：中国大陆
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T34133Primordazine NC-6364997；化合物 T34133Primordazine NC 6364997|||Primordazine NC6364997；Primordazine NC 6
Primordazine NC-6364997 is a negative control for Primordazine A and Primordazine B.
价 格：￥电议型 号：T34133产 地：中国大陆
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T33785o-Iodohippurate sodium；化合物 T33785Hippodin|||NSC-63351|||Sodium iodohippurate NSC 63351|||NSC63351；Hi
o-Iodohippurate sodium is an analogue of p-aminohippuric acid used to determine effective renal plasma flow. Labelled OIH has a higher clearance than other radiopharmaceutical yet developed and is extremely suitable for renography. It is eliminated mainly by tubular secretion. In patients with normally functioning kidneys, 85% of the OIH may exist in the urine after intravenous injection for 30 minutes.
价 格：￥电议型 号：T33785产 地：中国大陆
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T33757NSC659000；化合物 T33757NSC-659000|||NSC 659000；NSC-659000|||NSC 659000
NSC659000 is a potential antifungal drug.
价 格：￥电议型 号：T33757产 地：中国大陆
