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T40008Pomalidomide-C6-I TFA;化合物Pomalidomide-C6-I TFAPomalidomide-C6-I TFA
Pomalidomide-C6-I TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
价 格:¥电议型 号:T40008产 地:中国大陆
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T40003Thalidomide-NH-C6-NH2 hydrochloride;化合物Pomalidomide-C6-NH2 hydrochlorideThalidomide-NH-C6-NH2 hydroc
Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
价 格:¥电议型 号:T40003产 地:中国大陆
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T40001Pomalidomide-C6-COOH;化合物Pomalidomide-C6-COOHPomalidomide-C6-COOH
Pomalidomide-C6-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
价 格:¥电议型 号:T40001产 地:中国大陆
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T39898(S,R,S)-AHPC-C6-NH2 hydrochloride;(S,R,S)-AHPC-C6-NH2 hydrochloride(S,R,S)-AHPC-C6-NH2 hydrochloride
(S, R, S)-AHPC-C6-NH2 hydrochloride (also known as VH032-C6-NH2 hydrochloride) is a synthetic E3 ligase ligand-linker conjugate. It combines the VH032-based VHL ligand with a linker designed for AKT PROTAC degrader applications.
价 格:¥电议型 号:T39898产 地:中国大陆
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T39872(S,R,S)-AHPC-C6-NH2 dihydrochloride;(S,R,S)-AHPC-C6-NH2 dihydrochloride(S,R,S)-AHPC-C6-NH2 dihydroch
(S, R, S)-AHPC-C6-NH2 dihydrochloride (also known as VH032-C6-NH2 dihydrochloride) is a synthesized compound that functions as a ligand-linker conjugate for E3 ligase. It incorporates the VH032-based VHL ligand along with a linker, which is used for the degradation of AKT PROTAC.
价 格:¥电议型 号:T39872产 地:中国大陆
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T39737NH2-PEG5-C6-Cl hydrochloride;NH2-PEG5-C6-Cl hydrochlorideNH2-PEG5-C6-Cl hydrochloride;NH2-PEG5-C6-Cl
NH2-PEG5-C6-Cl hydrochloride is a polyethylene glycol (PEG)-based linker compound, commonly employed in the synthesis of proteolysis targeting chimeras (PROTACs).
价 格:¥电议型 号:T39737产 地:中国大陆
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T39644Thalidomide-O-C6-COOH;Thalidomide-O-C6-COOHThalidomide-O-C6-COOH;Thalidomide-O-C6-COOH
Thalidomide-O-C6-COOH is a synthetic conjugate comprising an E3 ligase ligand-linker, which combines the Thalidomide derived cereblon ligand with a PROTAC technology linker.
价 格:¥电议型 号:T39644产 地:中国大陆
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T39512Thalidomide-NH-C6-NH-Boc;Thalidomide-NH-C6-NH-BocThalidomide-NH-C6-NH-Boc;Thalidomide-NH-C6-NH-Boc
Thalidomide-NH-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate containing the cereblon ligand derived from Thalidomide and a linker utilized in the synthesis of MI-389 (compound 22). MI-389 is a highly effective phthalimide PROTAC degrader developed from the multi-targeted receptor tyrosine kinase inhibitor sunitinib.
价 格:¥电议型 号:T39512产 地:中国大陆
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T3951NSC632839;化合物NSC632839F6|||Ubiquitin Isopeptidase Inhibitor II;F6|||Ubiquitin Isopeptidase Inhibitor
NSC-632839 (Ubiquitin Isopeptidase Inhibitor II) is a nonselective isopeptidase inhibitor, which inhibits USP2 (EC50: 45±4 μM), USP7 (EC50: 37±1 μM), and SENP2 (EC50: 9.8±1.8 μM).
价 格:¥电议型 号:T3951产 地:中国大陆
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T39361Thalidomide-O-amido-C6-NH2;Thalidomide-O-amido-C6-NH2E3LigaseLigand-LinkerConjugates25|||Cereblon Li
Thalidomide-O-amido-C6-NH2 (Cereblon Ligand-Linker Conjugates 11) is a Thalidomide-based synthetic E3 ligase ligand-linker conjugate, comprising of a cereblon ligand and a linker. This compound is employed in the production of PROTACs (proteolysis-targeting chimeras).
价 格:¥电议型 号:T39361产 地:中国大陆
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T39100Azido-PEG3-C6-Cl;Azido-PEG3-C6-ClAzido-PEG3-C6-Cl;Azido-PEG3-C6-Cl
Azido-PEG3-C6-Cl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39100产 地:中国大陆
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T38953Azido-C6-OH;化合物Azido-C6-OHAzido-C6-OH
Azido-C6-OH is a cleavable ADC linker used to synthesize antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T38953产 地:中国大陆
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T38755Rafoxanide 13C6雷复尼特13C6雷复尼特13C6
Rafoxanide 13C6 is a labeled Rafoxanide . Rafoxanide is a salicylanilide used as an antiparasitic agent.
价 格:¥电议型 号:T38755产 地:中国大陆
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T38742NSC639828;NSC639828NSC639828
NSC639828 is an efficient inhibitor of DNA polymerase α, exhibiting a remarkable IC50 value of 70 μM. Additionally, NSC639828 demonstrates substantial antitumor activity, making it a promising candidate for cancer research.
价 格:¥电议型 号:T38742产 地:中国大陆
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T38661NH2-PEG3-C6-Cl;NH2-PEG3-C6-ClNH2-PEG3-C6-Cl;NH2-PEG3-C6-Cl
NH2-PEG3-C6-Cl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T38661产 地:中国大陆
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T386384-Trifluoromethylsalicylic acid-13C6;4-Trifluoromethylsalicylic acid-13C64-Trifluoromethylsalicylic
4-Trifluoromethylsalicylic acid-13C6 is 13C-labeled 4-Trifluoromethylsalicylic acid, mainly used as a quantitative tracer in drug development. 4-Trifluoromethylsalicylic acid is also a platelet aggregation inhibitor.
价 格:¥电议型 号:T38638产 地:中国大陆
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T38035Phenol-13C6;Phenol-13C6Phenol-13C6;Phenol-13C6
Phenol-13C6is a building block.1It has been used in the synthesis of13C6-labeled metabolites of (±)-asenapine .
价 格:¥电议型 号:T38035产 地:中国大陆
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T3792813C6 Glucosylsphingosine (d18:1);13C6 Glucosylsphingosine (d18:1)13C6 Glucosylsphingosine (d18:1)
13C6 Glucosylsphingosine (d18:1) is an isotopically enriched form of 1-β-D-glucosylsphingosine (d18:1) that is intended for use as an internal standard for the quantification of 1-β-D-glucosylsphingosine by GC- or LC-MS. 1-β-D-Glucosylsphingosine is a lysolipid derivative of glucosylcerebroside that decreases activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner.
价 格:¥电议型 号:T37928产 地:中国大陆
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T37742N-hexanoyl-DL-Homoserine lactoneN-己酰基-DL-高丝氨酸内酯C6-HSL
N-hexanoyl-DL-Homoserine lactone (C6-HSL), isolated from bivalve larval cultures, degrades bacteria and inhibits lesions induced by the phytopathogenic fungus B. cinerea.N-hexanoyl-DL-Homoserine lactone participates in the bacterial N-acyl-homoserine lactone (AHL) community-sensing (QS) system. N-hexanoyl-DL-Homoserine lactone is involved in the N-acyl-homoserine lactone (AHL) community sensing (QS) system between bacteria.
价 格:¥电议型 号:T37742产 地:中国大陆
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T37565C6 D-threo Ceramide (d18:1/6:0);C6 D-threo Ceramide (d18:1/6:0)C6 D-threo Ceramide (d18:1/6:0);C6 D-
C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 D-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 μM but induces cell death at concentrations greater
价 格:¥电议型 号:T37565产 地:中国大陆