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T70541IS-145;化合物 IS-145IS-145
IS-145 is a thromboxane A2 receptor antagonist.
价 格:¥电议型 号:T70541产 地:中国大陆
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T70520TWS-119;化合物 TWS-119TWS-119
TWS-119 is an inhibitor of glycogen synthase kinase-3β (GSK-3β) that induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells (ESCs).
价 格:¥电议型 号:T70520产 地:中国大陆
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T70510CVS-1123;化合物 CVS-1123CVS-1123
CVS-1123 is a direct thrombin inhibitor, preventing occlusive arterial and venous thrombosis in a canine model of vascular injury.
价 格:¥电议型 号:T70510产 地:中国大陆
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T70435BMS-187745;化合物 BMS-187745BMS-187745
BMS-187745 is a squalene synthase inhibitor.
价 格:¥电议型 号:T70435产 地:中国大陆
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T70287BMS-186511;化合物 BMS-186511BMS-186511
BMS-186511 is a Farnesyltransferase (FT) inhibitor with potential anticancer activity. BMS-186511 is a bisubstrate analogue inhibitor of FT, would inhibit the malignant growth properties of a cell line established from malignant schwannoma of an NF1 patient. Following treatment with BMS-186511 , ST88-14 cells became flat, nonrefractile, were contact-inhibited, and lost their ability to grow in soft agar. BMS-186511 was found to specifically inhibit FT, but not geranylgeranyltransferase I, a clos
价 格:¥电议型 号:T70287产 地:中国大陆
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T70110CVS-1578;化合物 CVS-1578CVS-1578
CVS-1578 is a potent serine protease inhibitor, targeting the S2S3 thrombin and FXa subsites.
价 格:¥电议型 号:T70110产 地:中国大陆
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T69959NAS-181 free base;化合物 NAS-181 free baseNAS-181 free base
NAS-181 free base is a 5-HT(1B) receptor antagonist.
价 格:¥电议型 号:T69959产 地:中国大陆
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T69771MS-177;化合物 MS-177MS-177
MS177, a potent and rapid EZH2 degrader, functions as a PROTAC comprised of a CRBN ligand, linker, and a powerful enzymatic EZH2 inhibitor C24 (C24 IC50: 12?nM). It successfully targets and depletes both canonical EZH2–PRC2 and noncanonical EZH2–cMyc complexes. Furthermore, MS177 inhibits leukemia cell growth, induces apoptosis, and arrests cell cycle progression.
价 格:¥电议型 号:T69771产 地:中国大陆
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T6973RS-127445;化合物RS-127445MT500;MT500
RS-127445 (MT500) is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4, exhibits >1000-fold selectivity against other 5-HT receptors.
价 格:¥电议型 号:T6973产 地:中国大陆
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T6972RS-1;化合物RS-1RS-1
RS-1 is a RAD51 activator. RS-1 also increases CRISPR/Cas9-mediated knock-in efficiencies.
价 格:¥电议型 号:T6972产 地:中国大陆
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T69701HS-152;化合物 HS-152HS-152
HS-152 is a novel reversible inhibitor of smurf1, directly targeting the catalytic activity of smurf hect domains, significantly blocking auto-ubiquitination and the transfer of ubiquitin from hect domain to the substrates to form isopeptide bond
价 格:¥电议型 号:T69701产 地:中国大陆
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T69696TAS-108 citrate;化合物 TAS-108 citrateTAS-108 citrate
TAS-108, also known as SR16234, is a synthetic, antiestrogenic steroidal compound with potential antitumor activity. TAS-108 binds to and inhibits estrogenic receptor alpha (ERa), mainly expressed in the mammary gland and uterus and upregulated in estrogen-dependent tumors. Blockage of ERa by TAS-108 prevents the binding and effects of estrogen and may lead to an inhibition of estrogen-dependent cancer cell proliferation. TAS-108 also is a partial agonist of the estrogenic receptor beta (ERb), e
价 格:¥电议型 号:T69696产 地:中国大陆
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T6907NPS-1034;化合物NPS-1034NPS1034|||NPS 1034;NPS1034|||NPS 1034
NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.
价 格:¥电议型 号:T6907产 地:中国大陆
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T68276Macimorelin acetate;化合物 Macimorelin AcetateEP-1572 acetate ; AEZS-130 acetate|||AEZS-130 acetate|||
Macimorelin Acetate (EP-1572), an orally active growth hormone (GH) secretagogue and a ghrelin receptor (GHSR) agonist, stimulates GH release. It is utilized in research focusing on adult growth hormone deficiency (AGHD) and Cancer Anorexia-Cachexia Syndrome (CACS).
价 格:¥电议型 号:T68276产 地:中国大陆
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T6815HS-1371;化合物HS1371HS-1371
HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.
价 格:¥电议型 号:T6815产 地:中国大陆
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T68037LCBS-1114 HCl;CBS-1114盐酸盐N-Phenylbenzamidrazone hydrochloride|||cbs-1114 HCl(46721-85-1 Free base);N-
CBS-1114 HCl (N-Phenylbenzamidrazone hydrochloride) is a 5-lipoxygenase inhibitor and an anti-inflammatory compound in a good eye-permeable model.CBS-1114 HCl maintains and improves cardiac function, attenuates cardiac dysfunction, as well as reduces epicardial adipose tissue and/or pericardial adipose tissue in subjects with cardiovascular disease.
价 格:¥电议型 号:T68037L产 地:中国大陆
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T6595Moexipril hydrochloride;莫昔普利盐酸盐Moexipril HCl|||RS-10085|||SPM 925|||CI-925;莫昔普利盐酸盐|||Moexipril HCl||
Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure.
价 格:¥电议型 号:T6595产 地:中国大陆
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T6311Bafetinib;巴氟替尼NS-187|||INNO-406;NS-187|||巴氟替尼|||INNO-406
Bafetinib (INNO-406) (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5.8/19 nM), and no inhibition of the phosphorylation of the T315I mutant and less effective to c-Kit and PDGFR.
价 格:¥电议型 号:T6311产 地:中国大陆
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T6297Alvespimycin hydrochloride;阿螺旋霉素盐酸盐BMS 826476|||NSC 707545|||KOS-1022|||17-DMAG hydrochloride|||Alve
Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.
价 格:¥电议型 号:T6297产 地:中国大陆