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产品数:86101
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T9192BIIB068ADME,inhibit,FcγR,Autoimmune,Bruton tyrosine kinase,TNFα,BIIB 068,ROS,Inhibitor,reversible,Bt
BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.
价 格:¥电议型 号:T9192产 地:中国大陆
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T67769MPT0B014MPT0B014
MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis.
价 格:¥电议型 号:T67769产 地:中国大陆
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T9821ART-CHEM-BB B025267ART-CHEM-BB B-025267,ART CHEM BB B025267,ARTCHEMBB B025267
ART-CHEM-BB B025267 is the upregulator of utrophin production with EC50 of 1.8 μM and can be used in research on the treatment of Duchenne muscular dystrophy.
价 格:¥电议型 号:T9821产 地:中国大陆
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T9446KB-0742 dihydrochlorideKB0742,inhibit,CDK,CDK9,KB-0742,KB 0742,Ser7,Ser2,CRPC,KB 0742 dihydrochlorid
KB-0742 dihydrochloride is a potent, selective and orally inhibitor of ?CDK9.
价 格:¥电议型 号:T9446产 地:中国大陆
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T9174IcerguastatIFB 088,Sephin1,Inhibitor,misfolding,Sephin-1,prion,Icerguastat,IFB088,stress,eIF2α,scler
Sephin1 is a selective inhibitor of holophosphatase. Sephin1 safely and selectively inhibited a regulatory subunit of protein phosphatase 1 in vivo.
价 格:¥电议型 号:T9174产 地:中国大陆
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T36899INCB086550
INCB086550 (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.
价 格:¥电议型 号:T36899产 地:中国大陆
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T10704CCB02CCB-02,CCB02
CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity. CCB02 shows no inhibition on the cell cycle- and centrosome-related kinases, or the phosphorylation status of Aurora-A, CDK2, Plk1, Plk2, and CHK1.
价 格:¥电议型 号:T10704产 地:中国大陆
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T22345INCB054329Inhibitor,inhibit,INCB 054329,Epigenetic Reader Domain
INCB054329, a structurally distinct bromodomain and extraterminal domain (BET) inhibitor, inhibits BRD2-BD1, BRD2-BD2, BRD3-BD1, BRD3-BD2, BRD4-BD1, BRD4-BD2, BRDT-BD1 and BRDT-BD2 with IC50 values of 44 nM, 5 nM, 9 nM, 1 nM, 28 nM, 3 nM, 119 nM and 63 nM respectively.
价 格:¥电议型 号:T22345产 地:中国大陆
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T6895TAK-580BIIB024,TAK-580,Raf kinases,inhibit,MLN-2480,TAK580,BIIB 024,TAK 580,Raf,Inhibitor,MLN 2480
MLN2480 is an oral, selective pan-Raf kinase inhibitor in Clinicalal trials.
价 格:¥电议型 号:T6895产 地:中国大陆
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T6278SotrastaurinAEB071;索曲妥林
Sotrastaurin is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).
价 格:¥电议型 号:T6278产 地:中国大陆
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T6156Ruxolitinib (S enantiomer)S-Ruxolitinib;INCB018424;INCB18424;Ruxolitinib S enantiomer;环丙基[4-[3-(1H-咪
Ruxolitinib S enantiomer is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.
价 格:¥电议型 号:T6156产 地:中国大陆
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T5804Pneumocandin B0纽莫康定B0;L-688786
Pneumocandin B0 is a natural product and a key intermediate in the synthesis of the antifungal agent.
价 格:¥电议型 号:T5804产 地:中国大陆
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T5417INCB-057643INCB057643
INCB057643 is a potent, selective and orally bioavailable BET inhibitor.
价 格:¥电议型 号:T5417产 地:中国大陆
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T5103AKOS B018304(5E)-5-(2-硝基苯亚甲基)-2-硫代-四氢噻唑-4-酮
AKOS B018304 is an arylalkylidene derivative, with polar substitution at para-position.
价 格:¥电议型 号:T5103产 地:中国大陆
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T4656RAD51 Inhibitor B02B02
RAD51 Inhibitor B02 (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 μM.
价 格:¥电议型 号:T4656产 地:中国大陆
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T4165DelpazolidLCB01-0371
Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed goo
价 格:¥电议型 号:T4165产 地:中国大陆
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T4011NCB-0846NCB 0846;NCB0846
NCB-0846 is an orally active TNIK inhibitor (IC50: 21 nM).
价 格:¥电议型 号:T4011产 地:中国大陆
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T3998Itacitinib伊他替尼;INCB39110;INCB039110
Itacitinib is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.
价 格:¥电议型 号:T3998产 地:中国大陆
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T3043Ruxolitinib phosphate磷酸鲁索利替尼;INC 424 phosphate;INCB018424 phosphate;INC424;Ruxolitinib (INCB-18424)
Ruxolitinib phosphate(INCB018424 phosphate) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3.
价 格:¥电议型 号:T3043产 地:中国大陆