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T77940Tazemetostat de(methyl morpholine)-COOH;化合物 Tazemetostat de(methyl morpholine)-COOHTazemetostat de(m
Tazemetostat de(methyl morpholine)-COOH (compound 7), a PROTAC ligand for EZH2, facilitates the synthesis of PROTACs that target this enzyme. These EZH2 degraders exhibit potent inhibition of cell viability in diffuse large B-cell lymphoma (DLBCL) and other lymphoma subtypes [1].
价 格:¥电议型 号:T77940产 地:中国大陆
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T76794Ulocuplumab;乌洛鲁单抗BMS 936564|||MDX 1338;BMS 936564|||MDX 1338
Ulocuplumab (BMS-936564) is a fully human anti-CXCR4 IgG4 antibody.Ulocplumab exhibits antitumor activity in acute myeloid leukemia (AML), non-Hodgkin´s lymphoma (NHL), and multiple myeloma transplantation models.Ulocplumab inhibits the migration of chronic lymphocytic leukemia (CLL) cells under CXCR4 activation, induces apoptosis, and inhibits the growth and migration of cancer cells. Ulocplumab inhibits CXCL12-mediated chronic lymphocytic leukemia (CLL) cell migration in response to CXCR
价 格:¥电议型 号:T76794产 地:中国大陆
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T76672Aprutumab阿普卢妥单抗FGFR-moAb|||FGFR2-TTC|||BAY 1179470
Aprutumab (BAY 1179470) is a human FGFR2 monoclonal antibody with affinity to FGFR2 isoforms FGFR2-IIIB and FGFR2-IIIC. Aprutumab is commonly used to synthesize antibody-drug conjugates.
价 格:¥电议型 号:T76672产 地:中国大陆
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T76279L1Retatrutide sodium salt;Retatrutide钠盐Retatrutide sodium salt(2381089-83-2 free base)|||LY3437943 sod
Retatrutide sodium salt is a potent triple agonist peptide for glucagon receptor (GCGR), glucose-dependent proinsulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R) Retatrutide sodium salt is used in the study of type 2 diabetes and obesity.
价 格:¥电议型 号:T76279L1产 地:中国大陆
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T76279Retatrutide;瑞他鲁肽LY3437943;LY3437943
Retatrutide (LY3437943) is a triple agonist of the glucagon receptor, glucose-dependent insulinotropic polypeptide receptor, and glucagon-like peptide-1 receptor (GLP-1R), and inhibits GCGR, GIPR, and GLP-1R.Retatrutide can be used to study obesity.
价 格:¥电议型 号:T76279产 地:中国大陆
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T75794Acetyl-Calpastatin(184-210)(human) TFA;化合物 Acetyl-Calpastatin(184-210)(human) TFAAcetyl-Calpastatin(
Acetyl-Calpastatin(184-210)(human) TFA, a potent, selective, and reversible inhibitor of calpain, demonstrates Ki values of 0.2 nM for ?-calpain and 6 μM for cathepsin L, indicating high specificity and efficacy in inhibiting these enzymes [1] [2].
价 格:¥电议型 号:T75794产 地:中国大陆
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T7573LTFLLR-NH2 2TFA(197794-83-5(free base));化合物TFLLR-NH2 2TFATFLLR-NH2 2TFA(197794-83-5(free base))
TFLLR-NH2 2TFA(197794-83-5(free base)) is an agonist of PAR1 (EC50 :1.9 μM).
价 格:¥电议型 号:T7573L产 地:中国大陆
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T74794USP28-IN-4;USP28 抑制剂4USP28-IN-4
USP28-IN-4 is a potent USP28 inhibitor with an IC50 value of 0.04 μM against USP28. USP28-IN-4 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3 and UCHL5. USP28-IN-4 is cytotoxic to human colorectal and lung squamous carcinoma cells and dose-dependently downregulates c-Myc cellular levels through the ubiquitin-proteasome system. -proteasome system to dose-dependently downregulate cellular levels of c-Myc.
价 格:¥电议型 号:T74794产 地:中国大陆
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T7379418-Hydroxycortisol;化合物 18-Hydroxycortisol18-Hydroxycortisol
18-Hydroxycortisol, a cortisol derivative and steroidogenic intermediate, is an endogenous steroid secreted by the adrenal cortex. It serves as a useful biochemical marker in primary aldosteronism (PA) research [1].
价 格:¥电议型 号:T73794产 地:中国大陆
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T72794Millmerranone A;化合物 Millmerranone AMillmerranone A
Millmerranone A shows the acetylcholinesterase inhibitory property.
价 格:¥电议型 号:T72794产 地:中国大陆
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T71529NO 794;化合物 NO 794NO 794
NO 794 is a histamine H2-receptor antagonist.
价 格:¥电议型 号:T71529产 地:中国大陆
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T71239CNV-2197944;化合物 CNV-2197944CNV-2197944
CNV-2197944 is a novel, small molecule, state-dependent calcium channel blocker, designed to selectively inhibit highly active Cav2.2 channels.
价 格:¥电议型 号:T71239产 地:中国大陆
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T70794Nevirapine dimer;化合物 Nevirapine dimerNevirapine dimer
Nevirapine dimer is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
价 格:¥电议型 号:T70794产 地:中国大陆
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T69794HMN-1180;化合物 HMN-1180HMN-1180
HMN-1180 is a small molecule inhibitor of neuronal nitric oxide synthase.
价 格:¥电议型 号:T69794产 地:中国大陆
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T69360RO3244794;化合物 RO3244794RO3244794
RO3244794 is a selective prostacyclin (IP) receptor antagonist that can be used to study liver injury.
价 格:¥电议型 号:T69360产 地:中国大陆
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T68794ALT-946 free base;化合物 ALT-946 free baseALT-946 free base
ALT-946 free base is an inhibitor of advanced glycation that has been shown to improve severe nephropathy in the diabetic transgenic (mREN-2)27 rat.
价 格:¥电议型 号:T68794产 地:中国大陆
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T68244PF-04279405;化合物 PF-04279405PF-04279405
PF-04279405 is a potent and selective glucokinase activator.
价 格:¥电议型 号:T68244产 地:中国大陆
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T67949TMX-2164;化合物TMX-2164TMX-2164
TMX-2164, a potent and irreversible inhibitor of B-cell lymphoma 6 (BCL6), demonstrates an IC50 of 152 nM, indicating strong inhibitory efficacy. It exhibits prolonged target engagement and effectively inhibits cell proliferation.
价 格:¥电议型 号:T67949产 地:中国大陆
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T67948OY-101;化合物OY-101OY-101
OY-101, an orally active compound, serves as a potent and specific inhibitor of P-glycoprotein (P-gp). It has the capability to sensitize drug-resistant tumors and counteract tumor multidrug resistance efficiently. Compared to Tetrandrine [1], OY-101 demonstrates enhanced water-solubility, cytotoxicity, and reversal activity.
价 格:¥电议型 号:T67948产 地:中国大陆