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  • T79444HA-IN-1；化合物 HA-IN-1HA-IN-1

    HA-IN-1 (compound 5g), a high-affinity Hemagglutinin (HA) ligand, targets the trypsin cleavage site of HA to inhibit HA-mediated membrane fusion and decrease pulmonary virus titer in vivo. This compound emerges as a promising influenza A virus (IAV) inhibitor and anti-influenza agent [1].

    价 格：￥电议型 号：T79444产 地：中国大陆

  • T79443Syk-IN-8；化合物 Syk-IN-8Syk-IN-8

    Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells. It specifically inhibits PLCγ2 phosphorylation and is applicable for blood cancer research [1].

    价 格：￥电议型 号：T79443产 地：中国大陆

  • T79442DprE1-IN-7；化合物 DprE1-IN-7DprE1-IN-7

    DprE1-IN-7 (Compound 64) is a DprE1 inhibitor with potent anti-tuberculosis (TB) activity, demonstrating a minimum inhibitory concentration (MIC) of 1 μM against the Mtb H37Rv strain. It exhibits antimycobacterial effects on drug-resistant strains. Additionally, DprE1-IN-7 shows high microsomal stability and exhibits medium clearance [1].

    价 格：￥电议型 号：T79442产 地：中国大陆

  • T79441DprE1-IN-6；化合物 DprE1-IN-6DprE1-IN-6

    DprE1-IN-6 (Compound 56) is a DprE1 inhibitor with demonstrated anti-TB activity, exhibiting a minimum inhibitory concentration (MIC) of 1 μM against the Mtb H37Rv strain, along with efficacy against drug-resistant mycobacterial strains. Moreover, it possesses high microsomal stability and medium clearance [1].

    价 格：￥电议型 号：T79441产 地：中国大陆

  • T79440DprE1-IN-5；化合物 DprE1-IN-5DprE1-IN-5

    DprE1-IN-5 (Compound 10), a potent DprE1 inhibitor, exhibits anti-TB activity with an MIC of 4 μM against the Mtb H37Rv strain and demonstrates antimycobacterial efficacy against drug-resistant strains. Additionally, it possesses high microsomal stability [1].

    价 格：￥电议型 号：T79440产 地：中国大陆

  • T7944VPS34 inhibitor 1 (Compound 19, PIK-III analogue)；化合物VPS34PIK-III analogue；PIK-III analogue

    VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)

    价 格：￥电议型 号：T7944产 地：中国大陆

  • T79439c-Myc inhibitor 12；化合物 c-Myc inhibitor 12c-Myc inhibitor 12

    Compound 67h, also known as c-Myc inhibitor 12, is a potent inhibitor of c-Myc, exhibiting a pEC50 value of 6.4 [1].

    价 格：￥电议型 号：T79439产 地：中国大陆

  • T79438c-Myc inhibitor 11；化合物 c-Myc inhibitor 11c-Myc inhibitor 11

    c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in rat pharmacokinetic assays, making it suitable for cancer research [1].

    价 格：￥电议型 号：T79438产 地：中国大陆

  • T79437NAMPT degrader-3；化合物 NAMPT degrader-3NAMPT degrader-3

    NAMPT Degrader-3 (compound C5) is a NAMPT degrader that functions through a VHL- and proteasome-dependent mechanism. It exhibits cytotoxic properties and inhibits the proliferation of A2780 cells [1].

    价 格：￥电议型 号：T79437产 地：中国大陆

  • T79436AHR agonist 4；化合物 AHR agonist 4AHR agonist 4

    AHR agonist 4 (compound 24e), as an Aryl hydrocarbon receptor (AHR) agonist, modulates the immune equilibrium between Th17/22 and Treg cells. It is a lead compound under investigation for anti-psoriasis drugs and demonstrates efficacy in mitigating imiquimod (IMQ)-induced psoriasis-like skin lesions [1].

    价 格：￥电议型 号：T79436产 地：中国大陆

  • T79435Metallo-β-lactamase-IN-11；化合物 Metallo-β-lactamase-IN-11Metallo-β-lactamase-IN-11

    Metallo-β-lactamase-IN-11 (compound 5f), a potent inhibitor of Metallo-β-lactamases (MBLs), demonstrates efficacy against the bacterial metallophyllactamase CphA with an IC50 value of 45 ?M. At a concentration of 10 ?M, Metallo-β-lactamase-IN-11 inhibits NDM-1 by 49% and AIM-1 by 61%, indicating its potential application in research focused on countering antibiotic resistance [1].

    价 格：￥电议型 号：T79435产 地：中国大陆

  • T79434Antitumor agent-103；化合物 Antitumor agent-103Antitumor agent-103

    Antitumor Agent-103 (compound 24l) induces apoptosis and possesses antiproliferative and anti-colony formation properties. This compound halts the cell cycle at the G0/G1 phase, augments nitric oxide (NO) production, and demonstrates anti-tumor efficacy [1].

    价 格：￥电议型 号：T79434产 地：中国大陆

  • T79433AKR1C3-IN-10；化合物 AKR1C3-IN-10AKR1C3-IN-10

    AKR1C3-IN-10 (compound 5r), a selective inhibitor of AKR1C3 with an IC50 of 51 nM, demonstrates efficacy in a prostate cancer xenograft model [1].

    价 格：￥电议型 号：T79433产 地：中国大陆

  • T79432NXT-10796；化合物 NXT-10796NXT-10796

    NXT-10796 is an orally active, intestinally restricted agonist of the EP4 receptor [1].

    价 格：￥电议型 号：T79432产 地：中国大陆

  • T79431Mu opioid receptor antagonist 7；化合物 Mu opioid receptor antagonist 7Mu opioid receptor antagonist 7

    Compound 24, also known as Mu opioid receptor antagonist 7, is a potent, centrally-acting ?-opioid receptor (?OR) antagonist with an inhibitory concentration (IC50) of 29 ± 3.0 nM. It is valuable for pain and opioid use disorder research [1].

    价 格：￥电议型 号：T79431产 地：中国大陆

  • T79430μ opioid receptor agonist 3；化合物 μ opioid receptor agonist 3μ opioid receptor agonist 3

    Compound 20, identified as μ opioid receptor agonist 3, is a potent ?OR agonist that exhibits an EC50 value of 0.87 nM. It holds promise for research into pain management and neuropsychiatric disorders [1].

    价 格：￥电议型 号：T79430产 地：中国大陆

  • T7943Fluphenazine decanoate；癸氟奋乃静Fluphenazine decanoate

    Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia.

    价 格：￥电议型 号：T7943产 地：中国大陆

  • T79429Tubulin polymerization-IN-50；化合物 Tubulin polymerization-IN-50Tubulin polymerization-IN-50

    Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cell cycle arrest at the G2/M phase [1].

    价 格：￥电议型 号：T79429产 地：中国大陆

  • T79428AF-2112；化合物 AF-2112AF-2112

    AF-2112, a TEAD inhibitor derived from Flufenamic acid, significantly diminishes the expression of CTGF, Cyr61, Axl, and NF2.

    价 格：￥电议型 号：T79428产 地：中国大陆

  • T79427LM-41；化合物 LM-41LM-41

    LM-41, a Flufenamic acid-derived TEAD inhibitor, significantly reduces the expression of CTGF, Cyr61, Axl, and NF2, and inhibits the migration of human MDA-MB-231 breast cancer cells [1].

    价 格：￥电议型 号：T79427产 地：中国大陆

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