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T17192Ubiquitin Isopeptidase Inhibitor I, G5;Ubiquitin Isopeptidase 抑制剂INSC144303;NSC144303
Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively).
价 格:¥电议型 号:T17192产 地:中国大陆
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T17179Tulrampator化合物TulrampatorCX-1632|||S-47445
Tulrampator (S-47445) is an orally bioavailable positive AMPAR with antidepressant effects.
价 格:¥电议型 号:T17179产 地:中国大陆
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T17144TPA 023;化合物TPA 023TPA 023
TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).
价 格:¥电议型 号:T17144产 地:中国大陆
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T17044Tesaglitazar;替格列扎Tesaglitazar
Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARα and human PPARα were 13.4 μM and 3.6 μM, respectively, and 0.2 μM for rat PPARγ and human PPARγ. Tesaglitazar induced DNA synthesis and fibrosarcoma formation in rat subcutaneous mesenchymal cells.
价 格:¥电议型 号:T17044产 地:中国大陆
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T16944STK16-IN-1;化合物STK16-IN-1STK16-IN-1
STK16-IN-1 is an inhibitor of STK16 kinase (IC50: 295 nM).
价 格:¥电议型 号:T16944产 地:中国大陆
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T16882SID 3712249化合物 T16882MiR-544 Inhibitor 1
SID 3712249 is an inhibitor of the biogenesis of microRNA-544 (miR-544).
价 格:¥电议型 号:T16882产 地:中国大陆
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T16869Seletracetam;化合物 T16869Ucb 44212;Ucb 44212
Seletracetam is an analog of the antiepileptic agent Levetiracetam. Seletracetam is a small molecule SV2A modulator for the research of epilepsy.
价 格:¥电议型 号:T16869产 地:中国大陆
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T16844Sarmazenil;沙马西尼R-154513|||Ro 15-3505;R-154513|||Ro 15-3505
Sarmazenil (Ro 15-3505) is a partial inverse agonist at the benzodiazepine receptor with pro-convulsant properties and is used in the study of chronic hepatic encephalopathy (HE).
价 格:¥电议型 号:T16844产 地:中国大陆
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T16760RK-24466;化合物RK-24466KIN 001-51;KIN 001-51
RK-24466 (KIN 001-51) is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.
价 格:¥电议型 号:T16760产 地:中国大陆
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T16744Rhodamine 6G罗丹明6GBasic Red 1|||罗丹明6G|||罗丹明 6G
Rhodamine 6G (Basic Red 1) is a rhodamine analog useful in Pgp efflux assays. It can be widely used in characterizing the kinetics of MRP1- mediated efflux as a laser dye and potential mitochondrial probe.
价 格:¥电议型 号:T16744产 地:中国大陆
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T16731Rentiapril racemate;伦唑普利外消旋体(Rac)-SA-446|||SA-446 racemate|||(Rac)-Rentiapril;(Rac)-SA-446|||SA-446
Rentiapril racemate (SA-446 racemate) is the racemate of Rentiapril.Rentiapril racemate has anti-inflammatory activity and may be used in glaucoma research.
价 格:¥电议型 号:T16731产 地:中国大陆
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T16699PYZD-4409;化合物PYZD-4409PYZD-4409
PYZD-4409 is a selective UBA1 inhibitor with an IC50 of 20 μM. PYZD-4409 induces cell death in malignant cells and is preferentially cytotoxic to malignant cells over normal hematopoietic cells.
价 格:¥电议型 号:T16699产 地:中国大陆
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T16644Propargyl-PEG7-acid;化合物 T16644Propargyl-PEG7-acid
Propargyl-PEG7-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T16644产 地:中国大陆
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T16544Pivalopril;化合物 T16544Pivopril|||RHC 3659(S);Pivopril|||RHC 3659(S)
Pivalopril is a new orally active inhibitor of angiotensin-converting enzyme.
价 格:¥电议型 号:T16544产 地:中国大陆
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T16501PF-3644022;化合物PF-3644022PF-3644022
PF-3644022 is an effective, selective, and ATP-competitive MAPKAPK2 (MK2) inhibitor (IC50: 5.2 nM and a Ki of 3 nM). PF-3644022 potently inhibits TNFα production and has an anti-inflammatory effect. PF-3644022 also inhibits MK3 and p38 regulated/activated kinase (PRAK) (IC50s: 53 nM and 5.0 nM, respectively).
价 格:¥电议型 号:T16501产 地:中国大陆
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T16491PF-06446846 hydrochloride;化合物PF-06446846盐酸盐PF-06446846 hydrochloride
PF-06446846 hydrochloride, an orally active and highly selective inhibitor, targets Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) translation by inducing ribosomal stalling at approximately codon 34, effectively suppressing PCSK9 expression.
价 格:¥电议型 号:T16491产 地:中国大陆
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T16478PF-04447943化合物PF-04447943PF 04447943|||Edelinontrine|||PF04447943
PF-04447943 (Edelinontrine) is a potent and selective phosphodiesterase 9A inhibitor with an IC50 of 12 nM, which is 78-fold more selective than that used for other PDE family members (IC50>1000 nM).PF-04447943 exhibits anti-inflammatory activity, attenuates inflammatory responses by inhibiting oxidative stress, inflammation, and modulating T-cell polarization, and may be useful for research on sickle cell anemia.
价 格:¥电议型 号:T16478产 地:中国大陆
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T16449PD176252;化合物PD176252PD176252
PD176252 is a potent BB1 and BB2 antagonist with inhibitory effects on BB1 and BB2 receptors.PD176252 acts as a small molecule GRPR inhibitor and FPR1/FPR2 agonist to inhibit the growth and proliferation of a variety of cancer cells.
价 格:¥电议型 号:T16449产 地:中国大陆
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T16448PD173212;化合物PD173212PD173212
PD 173212 is a blocker that blocks N-type voltage sensitive calcium channel (Cav2.2). PD173212 (0.0017-1.7 μmol/kg, Intraperitoneal Injection.) dose-dependently reduced DNBS-induced visceral hypersensitivity in mice.
价 格:¥电议型 号:T16448产 地:中国大陆
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T16447β-Amino Acid Imagabalin Hydrochloride;化合物 T16447PD-0332334;PD-0332334
β-Amino Acid Imagabalin Hydrochloride is the voltage-dependent calcium channel ligand for the α2δ subunit.
价 格:¥电议型 号:T16447产 地:中国大陆