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T15347FR167344 free base;化合物 T15347FR167344 free base
FR167344 free base is an orally active and nonpeptide antagonist of bradykinin receptor B2. FR167344 free base displays a high-affinity binding to the B2 receptor (IC50: 65 nM). It has no binding affinity for the B1 receptor.
价 格:¥电议型 号:T15347产 地:中国大陆
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T15344Minocromil;米诺罗米FPL59360;米诺罗米|||FPL59360
Minocromil is a new agent of Anti-asthmatic.
价 格:¥电议型 号:T15344产 地:中国大陆
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T15244Ertugliflozin L-pyroglutamic acid;埃格列净PF-04971729 L-pyroglutamic acid;埃格列净|||PF-04971729 L-pyrogluta
Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM. Ertugliflozin L-pyroglutamic acid can be used for studies about the treatment of type 2 diabetes mellitus.
价 格:¥电议型 号:T15244产 地:中国大陆
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T15241ER-000444793;化合物ER-000444793ER-000444793
ER-000444793 is a potent mitochondrial permeability transition pore (mPTP) opening inhibitor and it also inhibits mPTP (IC50: 2.8 μM).
价 格:¥电议型 号:T15241产 地:中国大陆
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T15212Emamectin Benzoate;甲胺基阿维菌素苯甲酸盐MK-244;MK-244|||甲胺基阿维菌素苯甲酸盐
Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods, acts as a chloride channel activator.
价 格:¥电议型 号:T15212产 地:中国大陆
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T1517LBenserazide;化合物 T1517LRo-44602|||Ro44602|||Ro 44602|||Serazide;Ro-44602|||Ro44602|||Ro 44602|||Seraz
Benserazide is an inhibitor of dopa decarboxylase. It is often given with levodopa in the treatment of Parkinson´s to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose.
价 格:¥电议型 号:T1517L产 地:中国大陆
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T15144DMP 777;化合物 T15144L-694458;L-694458
DMP 777 is an orally active inhibitor of human leukocyte elastase.
价 格:¥电议型 号:T15144产 地:中国大陆
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T15050Danicamtiv;化合物DanicamtivMYK-491|||SAR 440181;MYK-491|||SAR 440181
Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency.
价 格:¥电议型 号:T15050产 地:中国大陆
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T15044D609;化合物D609D609
D609 (Tricyclodecan-9-yl-Xanthogenate) has a wide range of biological activities including antioxidant, antiapoptotic, anticholinergic, antitumor, anti-inflammatory, antiviral, antiproliferative, and neuroprotective activities.D609 acts by inducing competitive inhibition of PC-specific phospholipase C (PC-PLC) and sphingomyelin synthase (SMS). D609 acts by causing competitive inhibition of PC-specific phospholipase C (PC-PLC) and sphingomyelin synthase (SMS).
价 格:¥电议型 号:T15044产 地:中国大陆
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T14962CI-1044;化合物 T14962PD-189659;PD-189659
CI-1044 is an inhibitor of PDE4 (IC50s: 0.29, 0.08, 0.56, 0.09 μM for PDE4A5, PDE4B2, PDE4C2 and PDE4D3).
价 格:¥电议型 号:T14962产 地:中国大陆
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T14944CGS 15943;化合物CGS 15943CGS 15943
CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor. In transfected CHO cells, its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM , respectively.
价 格:¥电议型 号:T14944产 地:中国大陆
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T14935Elexacaftor;化合物ElexacaftorVX-445;VX-445
Elexacaftor (VX-445) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR) and it also facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface.
价 格:¥电议型 号:T14935产 地:中国大陆
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T14924Cenerimod;塞利莫德ACT-334441;ACT-334441
Cenerimod (ACT-334441) is an orally active, selective, and potent sphingosine 1-phosphate receptor (S1P1) agonist (EC50: 1 nM).Cenerimod inhibits multiple S1P isoforms and can be used to study murine experimental autoimmune encephalomyelitis (EAE) and murine scleroderma.
价 格:¥电议型 号:T14924产 地:中国大陆
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T14923Cefpiramide sodium头孢匹胺钠头孢匹胺钠|||SM-1652|||Wy-44635
Cefpiramide sodium (SM-1652; Wy-44635) is a Pseudomonas-active cephalosporin. It has a broad spectrum of antibacterial activity.
价 格:¥电议型 号:T14923产 地:中国大陆
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T14904CCT244747;化合物 T14904CCT244747
CCT244747 is a CHK1 inhibitor (IC50: 7.7 nM) and also abrogates G2 checkpoint (IC50: 29 nM).
价 格:¥电议型 号:T14904产 地:中国大陆
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T14844BX430;化合物BX430BX430
BX430 is used for chronic pain and cardiovascular disease and it is a potent and selective noncompetitive allosteric human P2X4 receptor channels antagonist with an IC50 of 0.54 μM. BX430 has species specificity.
价 格:¥电议型 号:T14844产 地:中国大陆
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T14744Boc-NH-PEG4-azide;化合物 T14744Boc-NH-PEG4-azide
Boc-NH-PEG4-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14744产 地:中国大陆
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T14674BMS-509744;化合物 T14674BMS-509744
BMS-509744 is an inhibitor of ATP competitive Itk (IC50: 19 nM).
价 格:¥电议型 号:T14674产 地:中国大陆
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T14644Bis-PEG5-PFP ester;化合物 T14644Bis-PEG5-PFP ester
Bis-PEG5-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14644产 地:中国大陆
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T14559BI 224436;化合物 T14559BI 224436
BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains.
价 格:¥电议型 号:T14559产 地:中国大陆