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T15644KAT681;化合物 T15644T0681;T0681
KAT681 is a liver selective thyromimetic.
价 格:¥电议型 号:T15644产 地:中国大陆
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T15622JNJ-54175446;化合物 JNJ-54175446JNJ-5446;JNJ-5446
JNJ-54175446 (JNJ-5446) is a CNS-permeable and selective P2X7 receptor antagonist that attenuates the release of IL-1β/IL-18 from microglia, and may be used in the study of depression.
价 格:¥电议型 号:T15622产 地:中国大陆
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T15610JFD00244化合物 T15610JFD 00244|||JFD-00244|||JFD00244
JFD00244 is an inhibitor of sirtuin 2 (SIRT2). It has an anti-tumor effect.
价 格:¥电议型 号:T15610产 地:中国大陆
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T15600Istaroxime;化合物 T15600PST2744;PST2744
Istaroxime is an effective inhibitor of Na+, K+-ATPase (IC50: 0.11 μM).
价 格:¥电议型 号:T15600产 地:中国大陆
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T15599Istaroxime hydrochloride化合物 T15599PST2744 hydrochloride
Istaroxime hydrochloride is an inhibitor of Na+/K+-ATPase (IC50: 0.11 μM). It also is a sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA 2) activator.
价 格:¥电议型 号:T15599产 地:中国大陆
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T15580Inolitazone dihydrochloride化合物 T15580RS5444 dihydrochloride|||CS-7017 dihydrochloride|||Efatutazone
Inolitazone dihydrochloride is an effective, high-affinity PPARγ agonist; its biological activity is dependent on PPARγ (IC50:0.8 nM) to inhibit cell growth. Inolitazone dihydrochloride enhances the role of cell cycle kinase inhibitor p21 WAF1/CIP1.
价 格:¥电议型 号:T15580产 地:中国大陆
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T15544Iberin;化合物IberinNSC 321801;NSC 321801
Iberin (NSC-321801) induces apoptosis and inhibits cell survival (IC50 = 2.3 μM). Iberin is an analog of sulforaphane.
价 格:¥电议型 号:T15544产 地:中国大陆
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T15449GW-406381化合物 T15449GW406381|||GW 406381
GW406381 is a highly selective inhibitor of cyclooxygenase-2 (COX-2). GW406381 also attenuates spontaneous ectopic discharge in the sural nerves of rats following chronic constriction injury.
价 格:¥电议型 号:T15449产 地:中国大陆
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T15448GW-1100;化合物 T15448GW-1100
GW-1100 is a selective antagonist of GPR40 (pIC50: 6.9). GW1100 also plays the role of a GPR40 inverse agonist.
价 格:¥电议型 号:T15448产 地:中国大陆
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T15447Guacetisal;呱西替柳Guacetisal
Guacetisal is extracted from the esterification reaction of acetylsalicylic acid with guaiacol which can be used for research on the treatment of chronic bronchitis.
价 格:¥电议型 号:T15447产 地:中国大陆
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T15446GT 949;化合物GT 949GT 949
GT 949 is a selective excitatory positive allosteric modulator of amino acid transporter-2 (EAAT2) (EC50: 0.26 nM).
价 格:¥电议型 号:T15446产 地:中国大陆
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T15444GSK962;化合物GSK962GSK962
GSK962 is a GSK963 inactive enantiomer. It can be used to confirm the on-target effects.
价 格:¥电议型 号:T15444产 地:中国大陆
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T15443GSK8814;化合物 T15443GSK8814
GSK8814 is a selective and ATAD2/2B bromodomain chemical probe and inhibitor (binding constant pKd=8.1 and a pKi=8.9 in BROMOscan). GSK8814 displays 500-fold selectivity for ATAD2 over BRD4 BD1. GSK8814 binds to ATAD2 and BRD4 BD1 (pIC50s: 7.3 and 4.6).
价 格:¥电议型 号:T15443产 地:中国大陆
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T15442GSK864;化合物 T15442GSK864
GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).
价 格:¥电议型 号:T15442产 地:中国大陆
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T15441GSK8573;化合物GSK8573GSK8573
GSK8573 is an inactive control compound for GSK2801. GSK8573 has binding activity to BRD9 (Kd of 1.04 μM).
价 格:¥电议型 号:T15441产 地:中国大陆
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T15440GSK376501A;化合物GSK376501AGSK376501A
GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.
价 格:¥电议型 号:T15440产 地:中国大陆
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T1544Olsalazine disodium;奥沙拉秦钠Dipentum|||Olsalazine Sodium;Dipentum|||奥沙拉秦钠|||Olsalazine Sodium
Olsalazine disodium (Dipentum) is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis.
价 格:¥电议型 号:T1544产 地:中国大陆
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T15396GN44028;化合物GN44028N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine;N-(2,
GN44028 (N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine) is a hypoxia-inducible factor inhibitor of (HIF)-1 (IC50: 14 nM). GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity. However, It can not be suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization.
价 格:¥电议型 号:T15396产 地:中国大陆
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T15370GANT 58;化合物GANT 58NSC 75503;4,44乔,4乔(2,3,4,5-Thiophentetrayl)tetrakis-pyridine|||NSC 75503
GANT 58 (NSC-75503) is a potent antagonist of Gli. Which inhibits GLI1-induced transcription (IC50: 5 μM).
价 格:¥电议型 号:T15370产 地:中国大陆
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T15365G-744;化合物 T15365G-744
G-744 is a selective and orally active inhibitor of Btk (IC50: 2 nM). G-744 is well-tolerated, metabolically stable. It also has an efficacious to treat arthritis.
价 格:¥电议型 号:T15365产 地:中国大陆