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T16446PD 407824化合物 PD 407824PD-407824
PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkpoint kinases Chk1 and WEE1 (IC50s: 47 and 97 nM, respectively).
价 格：￥电议型 号：T16446产 地：中国大陆
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T16445PD 144418；化合物 T16445PD 144418
PD 144418 displays potential antipsychotic activity. PD 144418 is a high affinity, potent and selective sigma 1 (σ1) receptor ligand (Ki: 0.08 nM and 1377 nM for σ1 and σ2 respectively). It shows devoid of any significant affinity for other receptors, ion channels, and enzymes.
价 格：￥电议型 号：T16445产 地：中国大陆
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T16444PD-118057；化合物PD-118057PD-118057
PD-118057 is a potent ether associated (hERG) potassium channel activator that shows no activity against hERG. PD-118057 inhibits the excitability of the membrane by activating the hERG channel. PD-118057 is a potential compound for the treatment of delayed repolarization in inherited or acquired long QT syndrome and congestive heart failure.
价 格：￥电议型 号：T16444产 地：中国大陆
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T16443PCS1055 dihydrochloride；化合物 T16443PCS1055 dihydrochloride
PCS1055 dihydrochloride is an effective, selective, and competitive muscarinic M4 receptor antagonist (IC50: 18.1 nM and a Kd: 5.72 nM). PCS1055 dihydrochloride is also a potent AChE inhibitor (IC50 s: 22 nM and 120 nM for electric eel and human AChE, respectively). PCS1055 dihydrochloride inhibits radioligand [3H]-NMS binding to the M4 receptor (Ki: 6.5 nM). PCS1055 dihydrochloride shows >100-fold selectivity over M1-, M3-, and M5-receptors and 30-fold selectivity at the M2 receptor.
价 格：￥电议型 号：T16443产 地：中国大陆
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T16442PCO371；化合物PCO3712,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-
PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormone receptor 1. It has no effect on PTH type 2 receptor.
价 格：￥电议型 号：T16442产 地：中国大陆
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T16441PCI-33380；化合物 T16441PCI-33380
PCI-33380 is an irreversible inhibitor of Bruton´s Tyrosine Kinase.
价 格：￥电议型 号：T16441产 地：中国大陆
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T16440Ibrutinib Racemate化合物 T16440PCI-32765 (Racemate)
Ibrutinib is a selective, irreversible Btk inhibitor (IC50: 0.5 nM). Ibrutinib Racemate is the racemate of Ibrutinib.
价 格：￥电议型 号：T16440产 地：中国大陆
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T1644Dopamine hydrochloride；盐酸多巴胺Dopamine HCl|||ASL279；盐酸多巴胺|||Dopamine HCl|||ASL279
Dopamine hydrochloride (ASL279) is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine hydrochloride binds to alpha-1- and beta-1- adrenergic receptors.
价 格：￥电议型 号：T1644产 地：中国大陆
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T16344NS-2028；化合物NS-2028NS-2028
NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity). It is commonly used in the research of nitric oxide signaling pathways. NS-2028 inhibits soluble Guanylyl Cyclase activity in homogenates of mouse cerebellum and neuronal NO synthase (IC50: 17 nM and 20 nM). NS-2028 inhibits 3-morpholino-sydnonimine (SIN-1)-elicited formation of cyclic GMP in human cultured umbilical vein endothelial cells (IC50: 30 nM). NS
价 格：￥电议型 号：T16344产 地：中国大陆
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T16244N-(PEG2-C2-acid)-N-bis(PEG2-propargyl)；化合物 T16244N-(PEG2-C2-acid)-N-bis(PEG2-propargyl)
N-(PEG2-C2-acid)-N-bis(PEG2-propargyl) is a polyethylene glycol (PEG)-based linker compound designed for the synthesis of PROTACs[1].
价 格：￥电议型 号：T16244产 地：中国大陆
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T16164MY-5445；化合物MY-5445N-(3-chlorophenyl)-4-phenylphthalazin-1-amine；N-(3-chlorophenyl)-4-phenylphthalazi
MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5). MY-5445 selectively inhibits cGMP PDE (Ki:1.3 μM).
价 格：￥电议型 号：T16164产 地：中国大陆
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T16145MS-444化合物 T16145BE-34776
MS-444 suppresses the activity of purified smooth muscle myosin light chain kinase (MLCK) (IC50: 10 μM).
价 格：￥电议型 号：T16145产 地：中国大陆
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T16144MRX-2843；化合物MRX-2843UNC2371；UNC2371
MRX-2843 (UNC2371) is a potent and orally active inhibitor of MERTK and FLT3(IC50s of 1.3 nM and 0.64 nM, respectively).
价 格：￥电议型 号：T16144产 地：中国大陆
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T16107ML230；化合物 T16107CID44640177|||SID 88095709；CID44640177|||SID 88095709
ML230 is a selective ATP-binding cassette (ABC) transporter ABCG2 inhibitor. It 36-fold selective for ABCG2 over ABCB1 (EC50s: 0.13 μM and 4.65 μM, respectively).
价 格：￥电议型 号：T16107产 地：中国大陆
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T16044Methoprene；烯虫酯ZR-515；烯虫酯|||ZR-515
Methoprene (ZR-515) is a juvenile hormone (JH) mimic and a biological pesticide. Methoprene acts as an insect growth regulator interfering with the lifecycles of insects and preventing insects from reaching maturity or reproducing.
价 格：￥电议型 号：T16044产 地：中国大陆
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T1597Proadifen hydrochloride；盐酸丙基解痉素U-5446|||RP-5171|||SKF-525A；U-5446|||RP-5171|||SKF-525A|||盐酸丙基解痉素
Proadifen hydrochloride (RP-5171) is an inhibitor of drug metabolism and cytochrome P-450 enzyme system activity.
价 格：￥电议型 号：T1597产 地：中国大陆
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T15944M77976；化合物M77976M77976
M77976 is a selective ATP-competitive inhibitor of pyruvate dehydrogenase kinase 4 (PDK4) with an inhibitory effect on PDK4, having an IC50 value of 648 μM. It is used for research related to obesity and diabetes.
价 格：￥电议型 号：T15944产 地：中国大陆
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T15943M443；化合物 M443M443
M443 is a potent small molecule inhibitor of MRK that inhibits radiation-induced activation of p38 and Chk2 and can be used in cancer research.
价 格：￥电议型 号：T15943产 地：中国大陆
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T15844m-PEG2-azide；化合物 T15844m-PEG2-azide
m-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
价 格：￥电议型 号：T15844产 地：中国大陆
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T15722Lavoltidine；化合物 T15722Loxtidine|||AH-234844；Loxtidine|||AH-234844
Lavoltidine is an orally active and irreversible histamine H2-receptor antagonist. Lavoltidine strongly suppresses gastric acid secretion and also induces hypergastrinemia.
价 格：￥电议型 号：T15722产 地：中国大陆
