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T39106BMSpep-57；BMSpep-57BMSpep-57
BMSpep-57, a potent macrocyclic peptide inhibitor, competitively disrupts the PD-1/PD-L1 interaction, demonstrating a significant inhibitory concentration (IC50) of 7.68 nM. It exhibits binding affinity towards PD-L1 with dissociation constants (Kd) of 19 nM and 19.88 nM in MicroScale Thermophoresis (MST) and Surface Plasmon Resonance (SPR) assays, respectively. This compound enhances T cell functionality by promoting Interleukin-2 (IL-2) production within Peripheral Blood Mononuclear Cells (PBM
价 格：￥电议型 号：T39106产 地：中国大陆
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T38959BMS-604992 dihydrochlorideBMS-604992 dihydrochlorideEX-1314 dihydrochloride|||BMS-604992 dihydrochlo
BMS-604992 (EX-1314) dihydrochloride is a selective and orally active small-molecule agonist of the growth hormone secretagogue receptor (GHSR). It exhibits high-affinity binding (k i = 2.3 nM) and potent functional activity (EC 50 = 0.4 nM). Furthermore, BMS-604992 dihydrochloride has been shown to stimulate food intake in rodents.
价 格：￥电议型 号：T38959产 地：中国大陆
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T38922BMS-963272；化合物 BMS-963272BMS-963272
BMS-963272 is a selective and potent MGAT2 inhibitor with an IC50 value of 7.1 nM used in the study of metabolic disorders and obesity.
价 格：￥电议型 号：T38922产 地：中国大陆
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T38789BMS-984923；BMS-984923BMS-984923
BMS-984923, a highly potent silent allosteric modulator (SAM) of mGluR5, demonstrates exceptional binding affinity (K i = 0.6 nM). Additionally, this compound possesses favorable oral bioavailability and blood-brain barrier (BBB) penetration. BMS-984923 effectively inhibits the interaction between PrPC and mGluR5, preventing pathological Aβo signaling, while leaving physiological glutamate signaling unaffected.
价 格：￥电议型 号：T38789产 地：中国大陆
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T38397BMS-753426；BMS-753426BMS-753426
BMS-753426 is a potent and orally bioavailable antagonist of CCR2 .
价 格：￥电议型 号：T38397产 地：中国大陆
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T36885BMSpep-57 hydrochloride；BMSpep-57 hydrochlorideBMSpep-57 hydrochloride
BMSpep-57 hydrochloride, a potent macrocyclic peptide, competitively inhibits PD-1/PD-L1 interaction, exhibiting an IC50 value of 7.68 nM. It binds to PD-L1 with dissociation constants (Kds) of 19 nM and 19.88 nM as determined by MST and SPR assays, respectively. This compound enhances T cell functionality by promoting IL-2 production in PBMCs[1].
价 格：￥电议型 号：T36885产 地：中国大陆
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T36695TAS-103；TAS-103 (BMS-247615)TAS-103
TAS-103 is a dual inhibitor of DNA topoisomerase I/II, used for cancer research.
价 格：￥电议型 号：T36695产 地：中国大陆
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T3655BMS-1；化合物PD-1/PD-L1 inhibitor 1PD1-PDL1 inhibitor 1|||PD-1/PD-L1 inhibitor 1；PD1-PDL1 inhibitor 1|||
BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.
价 格：￥电议型 号：T3655产 地：中国大陆
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T36139BMS-795311；BMS 795311BMS-795311
Potent cholesteryl ester transfer protein (CETP) inhibitor (IC50 = 4 nM in an enzyme-based scintillation proximity assay). Inhibits cholesteryl ester transfer and increases HDL-C levels in vivo. Orally bioavailable.
价 格：￥电议型 号：T36139产 地：中国大陆
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T35856BMS-986176；化合物BMS-986176BMS-986176
AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).
价 格：￥电议型 号：T35856产 地：中国大陆
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T35386Elotuzumab；依洛妥珠单抗Elotuzumab (anti-SLAMF7)|||BMS 901608|||PDL 063|||HuLuc 63；Elotuzumab (anti-SLAMF7)
Elotuzumab(HuLuc 63) is a monoclonal antibody that targets the SLAMF7 receptor.Elotuzumab is a compound that directly activates NK cells and induces antibody-dependent cytotoxicity, and can be used in combination with lenalidomide and dexamethasone (Ld) to treat multiple myeloma.
价 格：￥电议型 号：T35386产 地：中国大陆
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T3523Fostemsavir；磷坦姆沙韦BMS-663068；BMS-663068|||磷坦姆沙韦
Fostemsavir (BMS-663068) is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.
价 格：￥电议型 号：T3523产 地：中国大陆
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T3495Tasimelteon；他司美琼VEC-162|||BMS-214778；他司美琼|||VEC-162|||BMS-214778
Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.
价 格：￥电议型 号：T3495产 地：中国大陆
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T3462BMS-582949 hydrochloride；化合物BMS-582949 HClBMS-582949 HCl；BMS-582949 HCl
The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).
价 格：￥电议型 号：T3462产 地：中国大陆
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T32737Liafensine；立阿芬辛BMS820836|||BMS 820836|||DB104|||BMS-820836；BMS820836|||BMS 820836|||DB104|||BMS-8208
Liafensine(BMS-820836) is a novel and selective triple monoamine reuptake inhibitor with inhibitory effects on the reuptake of serotonin, norepinephrine, and dopamine for the study of major depressive disorder and central nervous system disorders.
价 格：￥电议型 号：T32737产 地：中国大陆
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T31734BMS-604992；化合物 T31734EX1314|||EX-1314 HCl|||EX-1314|||BMS604992|||EX-1314 hydrochloride, BMS-604992|
EX-1314 (BMS-604992) is a growth hormone secretagogue receptor (GHSR) agonist.
价 格：￥电议型 号：T31734产 地：中国大陆
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T31605Edonentan；艾多南坦BMS207940|||BMS-207940|||BMS 207940；BMS207940|||BMS-207940|||BMS 207940
Edonentan is A potent endothelin A (ETA) receptor antagonist that can be used to study heart failure.
价 格：￥电议型 号：T31605产 地：中国大陆
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T3146BMS-202；化合物PD1-PDL1 inhibitor 2PD1-PDL1 inhibitor 2|||PD-1/PD-L1 inhibitor 2；PD1-PDL1 inhibitor 2|||
BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.
价 格：￥电议型 号：T3146产 地：中国大陆
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T30791Censavudine；化合物CensavudineOBP 601|||BMS 986001|||BMS-986001|||OBP601|||BMS986001|||OBP-601；OBP 601||
Censavudine (OBP-601) is a nucleoside analog, a nucleoside reverse transcriptase inhibitor, used for the prevention and treatment of human immunodeficiency virus 1 (HIV-1).Censavudine inhibits HIV-2 and HIV-1. Censavudine inhibits HIV-2 and HIV-1 with EC50 ranges of 30-81 nM and 450-890 nM, respectively.
价 格：￥电议型 号：T30791产 地：中国大陆
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T30576Brasofensine；化合物 T30576BMS-204756|||CID9554198|||BMS204756|||UNII-1YP2S94RVH|||BMS 204756；BMS-204756
Brasofensine is a monoamine reuptake blocker, which is a benztoalkane. In animal models of Parkinson´s disease, Brasofensine is effective in stimulating LMA and reversing motor inactivity. Brasofensine is being developed to treat Parkinson´s disease and Alzheimer´s disease.
价 格：￥电议型 号：T30576产 地：中国大陆
