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T62480Antitumor agent-51;化合物 Antitumor agent-51Antitumor agent-51
Antitumor agent-51 is effective and selective in inhibiting the growth and migration of osteosarcoma cells, acting on MNNG/HOS cells (IC50: 21.9 nM). antitumor agent-51 is less toxic and extremely bioavailable.
价 格:¥电议型 号:T62480产 地:中国大陆
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T62456ALR1/2-IN-1;化合物 ALR1/2-IN-1ALR1/2-IN-1
ALR1/2-IN-1 (Compound 6e) is an aldehyde reductase (ALR1) (IC50: 3.26 μM) and aldose reductase (ALR2) (IC50: 3.06 μM) inhibitor with anticancer effects.
价 格:¥电议型 号:T62456产 地:中国大陆
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T62414Dyrk1A-IN-1;化合物 Dyrk1A-IN-1Dyrk1A-IN-1
Dyrk1A-IN-1 is a triple inhibitor of Dyrk1A kinase activity, aggregation of tau and α-syn oligomers, with an IC50 value of 119 nM for Dyrk1A kinase.
价 格:¥电议型 号:T62414产 地:中国大陆
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T62394ALK5-IN-31;化合物 ALK5-IN-31ALK5-IN-31
ALK5-IN-31 is a selective inhibitor of ALK-5 (IC50≤10 nM) and also inhibits TGF-β-induced SMAD signalling.ALK5-IN-31 has the potential to inhibit tumour growth in vivo.ALK5-IN-31 can be used in the study of proliferative diseases (e.g. cancer, fibrotic diseases, systemic sclerosis).
价 格:¥电议型 号:T62394产 地:中国大陆
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T62348A1AR antagonist 3;化合物 A1AR antagonist 3A1AR antagonist 3
A1AR antagonist 3 (compound 13) is a selective adenylate 1 (A1) receptor antagonist that acts on human A1 (Ki: 9.69 nM) and rat A1 (Ki: 0.529 nM). A1AR antagonist 3 can be used to study neurological diseases.
价 格:¥电议型 号:T62348产 地:中国大陆
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T62333Anti-Trypanosoma cruzi agent-1;化合物 Anti-Trypanosoma cruzi agent-1Anti-Trypanosoma cruzi agent-1
Anti-Trypanosoma cruzi agent-1 (Compd E5) has a potent anti-Toxoplasma effect.
价 格:¥电议型 号:T62333产 地:中国大陆
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T62331Autophagy-IN-1;化合物 Autophagy-IN-1Autophagy-IN-1
Autophagy-IN-1 is a potent inhibitor of autophagy/mitophagy, blocking autophagosomal-lysosomal fusion in cancer cells while selectively increasing autophagic flux. Autophagy-IN-1 significantly inhibits tumour growth in the HCT116 mouse xenograft tumour model with low toxicity.Autophagy-IN-1 can be used to study colorectal cancer.
价 格:¥电议型 号:T62331产 地:中国大陆
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T62307Aha1/Hsp90-IN-1;化合物 Aha1/Hsp90-IN-1Aha1/Hsp90-IN-1
Aha1/Hsp90-IN-1 (Compound 17) is an inhibitor of the Aha1/Hsp90 complex and has an inhibitory effect on tau protein aggregation.Aha1/Hsp90-IN-1 disrupts the Aha1/Hsp90 interaction (IC50: 3.32 μM).
价 格:¥电议型 号:T62307产 地:中国大陆
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T62300Antimalarial agent 11;化合物 Antimalarial agent 11Antimalarial agent 11
Antimalarial agent 11 (compound 1) is a potent antimalarial agent, a spirocyclic chromane. Antimalarial agent 11 is able to act on D6 (EC50: 1.48 μM) and ARC08-022 (EC50: 1.81 μM).
价 格:¥电议型 号:T62300产 地:中国大陆
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T62291Anti-melanoma agent 1;化合物 Anti-melanoma agent 1Anti-melanoma agent 1
Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent that induces apoptosis.
价 格:¥电议型 号:T62291产 地:中国大陆
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T62284Anti-inflammatory agent 21;化合物 Anti-inflammatory agent 21Anti-inflammatory agent 21
Anti-inflammatory agent 21 (compound 9o) is a low cytotoxic, orally active anti-inflammatory agent that acts on NO (IC50: 0.76 μM). Anti-inflammatory agent 21 is able to accumulate ROS and block NF-κB/MAPK signaling pathway to exert anti-inflammatory effects. Anti-inflammatory agent 21 has a beneficial effect on cartilage destruction and inflammatory cell infiltration in a rat model of arthritis.
价 格:¥电议型 号:T62284产 地:中国大陆
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T62226Dyrk1A/α-synuclein-IN-2;化合物 Dyrk1A/α-synuclein-IN-2Dyrk1A/α-synuclein-IN-2
Dyrk1A/α-synuclein-IN-2 (Compound b20) is a dual inhibitor of Dyrk1A and α-synuclein aggregation that acts on α-synuclein (IC50: 7.8 μM). Dyrk1A/α-synuclein-IN-2 has a high predictive CNS permeability and neuroprotective effect.
价 格:¥电议型 号:T62226产 地:中国大陆
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T62195Analgesic agent-1;化合物 Analgesic agent-1Analgesic agent-1
Analgesic agent-1 is a potent analgesic that exhibits significant analgesic activity.
价 格:¥电议型 号:T62195产 地:中国大陆
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T62149ALM301;化合物 ALM301ALM301
ALM301 is a highly specific, orally active AKT inhibitor that acts on AKT1 (IC50: 0.13 μM), AKT2 (IC50: 0.09 μM) and AKT3 (IC50: 2.75 μM). ALM301 inhibits AKT phosphorylation in vitro and has a regulatory effect on downstream signalling. ALM301 exhibits inhibitory effects on cancer cell proliferation and tumor growth.
价 格:¥电议型 号:T62149产 地:中国大陆
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T62137ANKRD22-IN-1;化合物 ANKRD22-IN-1ANKRD22-IN-1
ANKRD22-IN-1 is a potent inhibitor of ANKRD22, which promotes the expansion of gastrointestinal mucosal epithelial stem cells and thus indirectly activates the Wnt classical pathway, which is beneficial for the recovery of damaged gastrointestinal mucosal tissue in vivo.
价 格:¥电议型 号:T62137产 地:中国大陆
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T62134A1/A3 AR antagonist 1;化合物 A1/A3 AR antagonist 1A1/A3 AR antagonist 1
A1/A3 AR antagonist 1 (Compound 10) is a potent, dual adenosine 1 (A1) and adenosine 3 (A3) receptor antagonist that acts on human A1 (Ki: 37.6 nM), human A3 (Ki: 25.4 nM) and rat A1 (Ki: 1.47 nM). 1 Can be used to study renal failure, inflammatory lung disease and Alzheimer´s disease.
价 格:¥电议型 号:T62134产 地:中国大陆
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T62127AMPA-IN-1;化合物 AMPA-IN-1AMPA-IN-1
AMPA-IN-1 is a potent inhibitor of AMPA receptors, a widely expressed receptor in the brain with a central role in the regulation of rapid excitatory synaptic transmission and synaptic plasticity. 14).
价 格:¥电议型 号:T62127产 地:中国大陆
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T62096Dyrk1A/α-synuclein-IN-1;化合物 Dyrk1A/α-synuclein-IN-1Dyrk1A/α-synuclein-IN-1
Dyrk1A/α-synuclein-IN-1 (Compound b1) is a dual inhibitor of Dyrk1A (IC50: 177 nM) and α-synuclein aggregation (IC50: 10.5 μM). CNS permeability and neuroprotective activity.
价 格:¥电议型 号:T62096产 地:中国大陆
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T62091Anti-hyperglycemic agent-1;化合物 Anti-hyperglycemic agent-1Anti-hyperglycemic agent-1
Anti-hyperglycemic agent 1 is a potent inhibitor of alpha-glucosidase (IC50: 0.53 μM). anti-Hyperglycemic agent 1 can be used to study diabetes.
价 格:¥电议型 号:T62091产 地:中国大陆
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T62078Akt/NF-κB/JNK-IN-1;化合物 Akt/NF-κB/JNK-IN-1Akt/NF-κB/JNK-IN-1
Akt/NF-κB/JNK-IN-1 (Compound 2i) is an inhibitor of Akt, NF-κB and JNK signalling pathways.Akt/NF-κB/JNK-IN-1 exhibits an inhibitory effect on nitric oxide production (IC50: 3.15 μM) and shows anti-inflammatory effects.
价 格:¥电议型 号:T62078产 地:中国大陆