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  • T60687A1AR antagonist 1；化合物 A1AR?antagonist 1A1AR antagonist 1

    A1AR antagonist 1 (compound 18g) is a potent antagonist of A1 adenosine receptor (AR). A1AR antagonist 1 has Ki values of 2.08, 6.91, and 31.2 nM for hA1, hA2A and hA2B, respectively [1].

    价 格：￥电议型 号：T60687产 地：中国大陆

  • T60615A1AR antagonist 6；化合物 A1AR antagonist 6A1AR antagonist 6

    A1AR antagonist 6 (compound 15) is a potent and selective antagonist of A1 adenosine receptor(A1AR) with a pKi of 7.13 and a pIC 50 of 6.38[1].

    价 格：￥电议型 号：T60615产 地：中国大陆

  • T60591A2AAR antagonist 1；化合物 A2AAR antagonist 1A2AAR antagonist 1

    A2AAR antagonist 1 (compound 21a) is an antagonist of A2AAR (adenosine A2A receptor) that shows high ligand efficiency with a Ki value of 20 nM. A2AAR antagonist 1 can be used in neurodegenerative disease research [1].

    价 格：￥电议型 号：T60591产 地：中国大陆

  • T60580A1AR antagonist 2；化合物 A1AR antagonist 2A1AR antagonist 2

    A1AR antagonist 2 (compound 18h) is a potent antagonist of the A1 adenosine receptor (AR). A1AR antagonist 2 has Ki values of 1.49, 10.2, and 50.1 nM for hA 1, hA 2A, and hA 2B, respectively [1].

    价 格：￥电议型 号：T60580产 地：中国大陆

  • T60570Anti-inflammatory agent 11；化合物 Anti-inflammatory agent 11Anti-inflammatory agent 11

    Anti-inflammatory agent 11 (compound 16) is a potent antimycobacterial agent that can be used in the research of tuberculosis(TB). Anti-inflammatory agent 11 inhibits the growth of Mtb H37Rv and M299 with MIC 50 of 1.3 and 6.9 μM, respectively. Anti-inflammatory agent 11 is also an anti-inflammatory agent that inhibits NO through the suppressing expression of iNOS and also inhibited the production of TNF-α and IL-1β [1].

    价 格：￥电议型 号：T60570产 地：中国大陆

  • T60550ALDH1A3-IN-1；化合物 ALDH1A3-IN-1ALDH1A3-IN-1

    ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].

    价 格：￥电议型 号：T60550产 地：中国大陆

  • T60450AChE/hCA I/II-IN-1；化合物 AChE/hCA I/II-IN-1AChE/hCA I/II-IN-1

    AChE/hCA I/II-IN-1 (Compound 6) is a potent AChE/Hca inhibitor with IC50 values of 22.21, 60.79 and 66.64 nM for AChE, Hca Ⅰ and Hca Ⅱ. AChE/hCA I/II-IN-1 can be used in glaucoma, Alzheimer´s disease, and diabetes rsearch[1].

    价 格：￥电议型 号：T60450产 地：中国大陆

  • T60410ART-IN-1；化合物 ART-IN-1ART-IN-1

    ART-IN-1 (compound 7) is a selective inhibitor of PARP with IC 50 s of 19, 22, 2.4, >100, 1.1 μM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively [1].

    价 格：￥电议型 号：T60410产 地：中国大陆

  • T60372ALDH3A1-IN-1；ALDH3A1 抑制剂 1ALDH3A1-IN-1

    ALDH3A1-IN-1 is a small molecule ALDH3A1 inhibitor, (IC50:1.61 μM), which can be used for the study of hyperprolinemia and dry-Larsen syndrome.

    价 格：￥电议型 号：T60372产 地：中国大陆

  • T60315Anti-infective agent 1；化合物 Anti-infective agent 1Anti-infective agent 1

    Anti-infective agent 1 (compound 3a) serves as a potent, selective antiprotozoal and antimycobacterial compound. It showcases antiparasitic efficacy against P. falciparum and T. brucei rhodesiense, demonstrating IC50 values of 10.95 and 0.06 μM, respectively. Moreover, it displays antimycobacterial properties against Mycobacterium smegmatis, exhibiting a minimum inhibitory concentration (MIC) of 8 μg/mL [1].

    价 格：￥电议型 号：T60315产 地：中国大陆

  • T60240ALDH1A3-IN-2；化合物ALDH1A3-IN-2ALDH1A3-IN-2

    ALDH1A3-IN-2 is a potent ALDH1A3 inhibitor with an IC50 of 0.30 μM.ALDH1A3-IN-2 has potential for cancer disease research.

    价 格：￥电议型 号：T60240产 地：中国大陆

  • T60205Antibacterial agent 171；抗菌剂 171Antibacterial agent 171

    (2S)-4-biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide is a LpxC inhibitor with IC50 >95.2 nM.

    价 格：￥电议型 号：T60205产 地：中国大陆

  • T60102ACT001；化合物 ACT001ACT001

    ACT001 is an orally active PAI-1 inhibitor by inhibiting the phosphorylation of PI3K and AKT. ACT001 inhibits the phosphorylation of STAT3 and PD-L1 expression by directly binding to STAT3. ACT001, a fumarate salt form of DMAMCL (a prodrug of Micheliolide), can cross the blood-brain barrier. ACT001 has a synergistic effect with cisplatin through the inhibition of the PAI-1/PI3K/AKT pathway. ACT001 has potent anti-glioblastoma (GBM) activity and immunomodulatory effects [1] [2].

    价 格：￥电议型 号：T60102产 地：中国大陆

  • T60003AC1-IN-1；化合物 AC1-IN-1AC1-IN-1

    AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 ?M).

    价 格：￥电议型 号：T60003产 地：中国大陆

  • T5622BAY-218；化合物AHR antagonist 1AHR antagonist 1；AHR antagonist 1

    BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.

    价 格：￥电议型 号：T5622产 地：中国大陆

  • T5618AK-1；化合物AK-1AK-1

    AK-1 is a sirtuin 2 (SIRT2) inhibitor (IC50:12.5 μM).that prevents hippocampal neurodegeneration in Alzheimer´s disease models and induces cell cycle arrest in colon carcinoma cells.

    价 格：￥电议型 号：T5618产 地：中国大陆

  • T5463Verdiperstat；化合物AZD3241AZD3241|||AZD 3241；AZD3241|||AZD 3241

    Verdiperstat (AZD 3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.

    价 格：￥电议型 号：T5463产 地：中国大陆

  • T5456WNK-IN-11；化合物WNK-IN-11Allosteric WNK Kinase Inhibitor；Allosteric WNK Kinase Inhibitor

    WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)

    价 格：￥电议型 号：T5456产 地：中国大陆

  • T5435ARV-771；化合物ARV-771ARV-771

    ARV-771 is a potent BET degrader based on PROTAC technology with Kds of 34, 4.7, 8.3, 7.6, 9.6, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1), and BRD4(2), respectively[1].

    价 格：￥电议型 号：T5435产 地：中国大陆

  • T5183AUT1；化合物AUT1AUT1

    AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).

    价 格：￥电议型 号：T5183产 地：中国大陆

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