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  • T36890A 410099.1；A 410099.1A 410099.1

    High affinity XIAP antagonist (Kd = 16 nM for the BIR3 domain of XIAP). Exhibits cytotoxicity in a wide range of cancer cell lines in vitro (EC50 = 13 nM in MDA-MB-231 cells). Also displays antitumor activity in a mouse breast cancer xenograft model. Enhances TRAIL-induced apoptosis in chronic lymphocytic leukemia (CLL) cells.

    价 格：￥电议型 号：T36890产 地：中国大陆

  • T36711FM19G11；化合物FM19G11FM19G11|||HIF-1alpha/2alpha Inhibitor；FM19G11|||HIF-1alpha/2alpha Inhibitor

    FM19G11 is an inhibitor of hypoxia inducible factor (HIF) α-subunit (IC50 = 80 nM in hypoxia induced luciferase assay).

    价 格：￥电议型 号：T36711产 地：中国大陆

  • T36649AN3661；AN3661AN3661

    AN3661, a potent antimalarial lead compound, targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue subunit 3 (PfCPSF3). AN3661 inhibits Plasmodium falciparum laboratory-adapted strains, Ugandan field isolates, and murine P. berghei and P. falciparum infections[1].

    价 格：￥电议型 号：T36649产 地：中国大陆

  • T36646Trastuzumab deruxtecan；德曲妥珠单抗DS-8201a|||VRN-101099|||DS 8201|||T-DXd；DS-8201a|||VRN-101099|||DS 8201

    Trastuzumab deruxtecan (T-DXd) is an antibody-activated molecule coupling (ADC) with anticancer and antitumour activity.Trastuzumab deruxtecan has been shown to have an ameliorative effect in HER2-positive breast and gastric cancers.

    价 格：￥电议型 号：T36646产 地：中国大陆

  • T36432A2ti-1化合物 A2ti-1A2ti-1

    A2ti-1 is a highly selective inhibitor of annexin A2/S100A10 heterotetramer (A2t) (IC50: 24 μM) that inhibits ARV-mediated activation of Src and p38 mitogen-activated protein kinase (MAPK). A2ti-1 can be used to study human papillomavirus type 16 (HPV16) infection.

    价 格：￥电议型 号：T36432产 地：中国大陆

  • T362191a,1b-dihomo Prostaglandin E1；1a,1b-dihomo Prostaglandin E11a,1b-dihomo Prostaglandin E1；1a,1b-dihom

    1a,1b-dihomo Prostaglandin E1 is a class of prostaglandin compounds.

    价 格：￥电议型 号：T36219产 地：中国大陆

  • T360451a,1b-dihomo Prostaglandin E2；1a,1b-dihomo Prostaglandin E21a,1b-dihomo Prostaglandin E2；1a,1b-dihom

    1a,1b-dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid . 1a,1b-dihomo PGE2 has also been identified in conditioned media of RAW 264.7 macrophages stimulated with endotoxin and arachidonic acid . This product is thought to be produced by elongation of AA to adrenic acid, which is then metabolized sequentially by COX and PGE synthase.

    价 格：￥电议型 号：T36045产 地：中国大陆

  • T3594617(R)-Resolvin D1；17(R)-Resolvin D1Aspirin-triggered Resolvin D1|||17(R)-Resolvin D1；Aspirin-trigger

    Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.[1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.[2] Resolvin D1 is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase.[1] 17(R)-RvD1 is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte (PMN) transendothelial migration, the ear

    价 格：￥电议型 号：T35946产 地：中国大陆

  • T35756Avermectin B1a monosaccharide；Avermectin B1a monosaccharideAvermectin B1a monosaccharide

    Avermectin B1a monosaccharide is a macrolide anthelmintic and monosaccharide form of avermectin B1a . It is lethal to C. elegans with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a monosaccharide also stimulates conductance in isolated shore crab muscle.

    价 格：￥电议型 号：T35756产 地：中国大陆

  • T35755Avermectin B1a aglycone；Avermectin B1a aglyconeAvermectin B1a aglycone

    Avermectin B1a aglycone is an aglycone form of the anthelmintic and insecticide avermectin B1a . It hyperpolarizes P. crassipes muscle fibers with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a aglycone decreases survival of C. elegans (MAC = 0.1 μM).

    价 格：￥电议型 号：T35755产 地：中国大陆

  • T35744Ivermectin B1a monosaccharide；Ivermectin B1a monosaccharideIvermectin B1a monosaccharide

    Ivermectin B1a monosaccharide is produced by selective hydrolysis of the terminal saccharide unit of ivermectin. It can inhibit nematode larval development, but does not cause paralytic activity. This compound has been used as a probe to detect some types of ivermectin resistance.

    价 格：￥电议型 号：T35744产 地：中国大陆

  • T35743Ivermectin B1a aglycone；Ivermectin B1a aglyconeIvermectin B1a aglycone

    Ivermectin B1a aglycone is an acid degradation product produced by hydrolysis of the disaccharide unit of ivermectin. It can inhibit nematode larval development, but does not cause paralytic activity.

    价 格：￥电议型 号：T35743产 地：中国大陆

  • T35587Ganglioside GD1a mixture (sodium salt)；Ganglioside GD1a mixture (sodium salt)Ganglioside B1；Ganglios

    Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. [1] It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (T

    价 格：￥电议型 号：T35587产 地：中国大陆

  • T35475aTAG 4531；aTAG 4531aTAG 4531

    Degrader of MTH1 fusion proteins for use within the aTAG system. Comprises a ligand selective for MTH1, a linker and the cereblon-binding ligand Thalidomide . Induces highly potent and selective degradation of fusion proteins after a 4 h incubation (DC50 = 0.34 nM; Dmax = 93.14%). Cell-permeable. Suitable for in vitro and in vivo applications. Mouse DMPK properties are provided in the supplementary file (see below). (MTH1 can be expressed as a fusion with a target protein of interest using genom

    价 格：￥电议型 号：T35475产 地：中国大陆

  • T35430Afatinib impurity 11；Afatinib impurity 11Afatinib impurity 11

    Afatinib impurity 11 is an impurity of Afatinib. Afatinib is an irreversible EGFR family inhibitor with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively[1].

    价 格：￥电议型 号：T35430产 地：中国大陆

  • T3540IMR-1A；化合物IMR-1AIMR-1A

    IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.

    价 格：￥电议型 号：T3540产 地：中国大陆

  • T35365LM11A-31；LM11A-31LM11A-31；LM11A-31

    LM11A-31 是一种小分子 p75NTR 配体，可逆转中晚期疾病进展的阿尔茨海默病小鼠模型中的胆碱能神经突营养不良。

    价 格：￥电议型 号：T35365产 地：中国大陆

  • T34361Ro 4-6824；化合物 T34361AI3-50843；AI3-50843

    Ro 4-6824 is a biochemical with immunosuppressive action.

    价 格：￥电议型 号：T34361产 地：中国大陆

  • T34321Rhododendrol, (+/-)-化合物 T34321AI3-31843

    Rhododendrol, (+/-)-, is an aromatic compound that may be useful in the treatment of hepatic diseases. However, this product is a known pro-oxidant which can be toxic to melanocytes.

    价 格：￥电议型 号：T34321产 地：中国大陆

  • T33961Phenamacide hydrochloride；化合物 T33961Aklonine；Aklonine

    Phenamacide hydrochloride is a biochemical.

    价 格：￥电议型 号：T33961产 地：中国大陆

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