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  • T4529ASP-9521；化合物ASP9521ASP9521；ASP9521

    ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).

    价 格：￥电议型 号：T4529产 地：中国大陆

  • T4506Gadopentetate dimeglumine；钆喷酸葡胺Meglumine gadopentetate|||SH-L-451A|||Gd-DTPA|||Gadopentetic acid dim

    Gadopentetate dimeglumine (Gd-DTPA), an extracellular intravenous contrast agent, is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRI.

    价 格：￥电议型 号：T4506产 地：中国大陆

  • T4380Ac-CoA Synthase Inhibitor1；化合物Ac-CoA Synthase Inhibitor1ACSS2 inhibitor；ACSS2 inhibitor

    Ac-CoA Synthase Inhibitor1 (ACSS2 inhibitor) is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2).

    价 格：￥电议型 号：T4380产 地：中国大陆

  • T4131Arjunic acid；化合物 T4131Arjunic acid

    Arjunic acid is a strong antioxidant and a free radical scavenger. Arjunic acid shows activity against Gram-positive and Gram-negative bacteria with MIC values ranging between 1.9 and 15.6 microg/mL.

    价 格：￥电议型 号：T4131产 地：中国大陆

  • T4125HSF1A；化合物HSF1AHSF1A

    HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis.

    价 格：￥电议型 号：T4125产 地：中国大陆

  • T41231GP 1a；化合物GP 1aGP 1a

    GP 1a is a potent agonist of cannabinoid receptor 2 (CB2) (EC50=7.1), as shown in cAMP, GTPγS and β-arrestin recruitment assays. GP 1a is approximately 30-fold more selective for CB2 receptors than CB1 receptors and increases P-ERK1/2 expression in HL-60 cells in vitro. GP 1a is beneficial for skin wound healing. GP 1a inhibits inflammation and fibrogenesis while promoting epithelial re-formation.

    价 格：￥电议型 号：T41231产 地：中国大陆

  • T40411ANATu00A0inhibitor-1；ANAT inhibitor-1ANATu00A0inhibitor-1

    ANAT Inhibitor-1 serves as an inhibitor of human aspartate N-acetyltransferase (ANAT), targeting Canavan disease.

    价 格：￥电议型 号：T40411产 地：中国大陆

  • T40338Antibacterial agent 31；Antibacterial agent 31Antibacterial agent 31

    Antibacterial agent 31 exhibits (shows) efficacy (activity) in combating (against) rice bacterial leaf streak.

    价 格：￥电议型 号：T40338产 地：中国大陆

  • T40307Adenosine receptor antagonist 1；Adenosine receptor antagonist 1Adenosine receptor antagonist 1

    Adenosine receptor antagonist 1 is a highly selective antagonist for the A2aR adenosine receptor, exhibiting an IC50 value of 0.29 nM. It demonstrates a remarkable 14-fold selectivity towards the A2aR receptor in comparison to the A2bR receptor.

    价 格：￥电议型 号：T40307产 地：中国大陆

  • T40117Antileishmanial agent-1；Antileishmanial agent-1Antileishmanial agent-1

    Antileishmanial agent-1 demonstrates activity against both L. amazonensis promastigotes (IC 50 = 15.52 μM) and intracellular amastigotes (IC 50 = 4.10 μM).

    价 格：￥电议型 号：T40117产 地：中国大陆

  • T40109APOL1-IN-1；APOL1抑制剂1APOL1-IN-1；APOL1-IN-1

    APOL1-IN-1 is a potent inhibitor of apolipoprotein L1 (APOL1) that can be used to study the pathogenesis of focal segmental glomerulosclerosis (FSGS) and nondiabetic kidney disease (NDKD), facilitating research into these diseases.

    价 格：￥电议型 号：T40109产 地：中国大陆

  • T40051Acid Ceramidase-IN-1；Acid Ceramidase-IN-1Acid Ceramidase-IN-1

    Acid Ceramidase-IN-1 is a highly effective and orally bioavailable inhibitor of acid ceramidase (AC, ASAH-1), with an inhibitory concentration (IC50) of 0.166 μM. Additionally, Acid Ceramidase-IN-1 exhibits exceptional brain penetration capabilities in mice.

    价 格：￥电议型 号：T40051产 地：中国大陆

  • T39932ARG1-IN-1ARG1-IN-1ARG1-IN-1

    ARG1-IN-1 is a human arginase 1 inhibitor with an IC 50 of 29 nM.

    价 格：￥电议型 号：T39932产 地：中国大陆

  • T39868Anticancer agent 11；Anticancer agent 11Anticancer agent 11

    Anticancer agent 11 an effective broad-spectrum anticancer agent, exerts its therapeutic potential by suppressing angiogenesis and facilitating the formation of DNA cross-links.

    价 格：￥电议型 号：T39868产 地：中国大陆

  • T39853ARD-61；ARD-61ARD-61

    ARD-61 is a potent and specific PROTAC androgen receptor (AR) degrader, exhibiting high effectiveness. It effectively induces the degradation of AR and progesterone receptors (PR) in AR+ cancer cell lines, leading to apoptosis. Additionally, ARD-61 demonstrates significant tumor growth inhibition in the MDA-MB-453 xenograft model in mice.

    价 格：￥电议型 号：T39853产 地：中国大陆

  • T39815anti-TNBC agent-1；anti-TNBC agent-1anti-TNBC agent-1

    anti-TNBC agent-1 is a highly effective compound specifically designed to target and combat triple-negative breast cancer (TNBC). It demonstrates remarkable potency against various breast cancer cell types, with IC50 values spanning from 0.20 μM to 0.27 μM. The mechanism of action of anti-TNBC agent-1 involves inducing apoptosis in SUM-159 cells through the mitochondria pathway, as well as causing G1 phase arrest in these cells.

    价 格：￥电议型 号：T39815产 地：中国大陆

  • T39813APJ receptor agonist 1；APJ receptor agonist 1APJ receptor agonist 1

    APJ receptor agonist 1, a potent biphenyl acid derivative, acts as an agonist (EC50 of 0.093 nM and 0.12 nM for human and rat APJ receptors, respectively) for the APJ receptor (APJ-R). It exhibits significant in vitro potency towards apelin-13, the endogenous peptidic ligand for the APJ receptor. APJ receptor agonist 1 holds promise for heart failure research.

    价 格：￥电议型 号：T39813产 地：中国大陆

  • T39781Aβ/tau aggregation-IN-1；Aβ/tau aggregation-IN-1Aβ/tau aggregation-IN-1

    Aβ/tau aggregation-IN-1 is a potent inhibitor of Aβ 1-42 β-sheet formation and tau aggregation. It exhibits K D values of 160 μM and 337 μM with Aβ 1-42 and tau, respectively. Additionally, Aβ/tau aggregation-IN-1 can penetrate the blood-brain barrier efficiently.

    价 格：￥电议型 号：T39781产 地：中国大陆

  • T39705ATG7-IN-1；化合物ATG7-IN-1ATG7-IN-1；ATG7-IN-1

    ATG7-IN-1 is a selective ATG7 inhibitor with an IC50 of 62 nM.

    价 格：￥电议型 号：T39705产 地：中国大陆

  • T39675ALDH1A2-IN-1ALDH1A2-IN-1ALDH1A2-IN-1

    ALDH1A2-IN-1 is a reversible inhibitor of the active site of ALDH1A2, showing a significant affinity for the enzyme with an IC50 value of 0.91 μM and a Kd value of 0.26 μM. This compound interacts hydrophobically with the enzyme, contributing to its inhibitory properties.

    价 格：￥电议型 号：T39675产 地：中国大陆

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