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T39594AKR1B10-IN-1AKR1B10-IN-1AKR1B10-IN-1
AKR1B10-IN-1, a powerful AKR1B10 (Aldo-Keto Reductase 1B10) inhibitor, demonstrates an IC50 value of 3.5 nM. This compound effectively curtails the proliferation, metastasis, and Cisplatin (CDDP) resistance of lung cancer cells.
价 格:¥电议型 号:T39594产 地:中国大陆
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T39566ZT-1a;化合物ZT-1aZT-1a
ZT-1a is a SPAK inhibitor.ZT-1a inhibits SPAK.ZT-1a can be used for the prevention and treatment of neurodegenerative and neurocognitive disorders.
价 格:¥电议型 号:T39566产 地:中国大陆
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T39335Anti-virus agent 1Anti-virus agent 1Anti-virus agent 1|||Remdesivir isopropyl ester analog
Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734, exhibits potent antiviral efficacy. It is primarily utilized in the study of coronavirus and Ebola virus (EBOV).
价 格:¥电议型 号:T39335产 地:中国大陆
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T39236Relamorelin acetate;Relamorelin acetateRelamorelin acetate|||RM-131 acetate|||BIM-28131acetate;Relam
Relamorelin (RM-131) acetate is a pentapeptide ghrelin analog that acts as a selective agonist for the ghrelin/growth hormone secretagogue receptor (GHSR). It exhibits a high affinity for the GHS-1a receptor, with a Ki value of 0.42 nM. Notably, Relamorelin acetate can cross the blood-brain barrier and target the central nervous system. This compound effectively increases growth hormone levels and promotes faster gastric emptying. Due to these properties, Relamorelin acetate holds promise for it
价 格:¥电议型 号:T39236产 地:中国大陆
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T39115ABR-238901;化合物ABR-238901ABR-238901
ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products) and TLR4 (toll-like receptor 4). ABR-238901 has potential as a compound for the treatment of myocardial infarction (MI).
价 格:¥电议型 号:T39115产 地:中国大陆
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T39089Acid secretion-IN-1;Acid secretion-IN-1Acid secretion-IN-1
Acid secretion-IN-1, a polycyclic compound, is synthesized for its application as an IDO inhibitor in synthetic experiments.
价 格:¥电议型 号:T39089产 地:中国大陆
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T39082AL-611;AL-611AL-611
AL-611 is an HCV NS5B polymerase inhibitor ( EC 50 = 5 nM).
价 格:¥电议型 号:T39082产 地:中国大陆
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T39002Azido-PEG1;Azido-PEG1Azido-PEG1;Azido-PEG1
Azido-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T39002产 地:中国大陆
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T38977Autophagy-IN-C1;Autophagy-IN-C1Autophagy-IN-C1;Autophagy-IN-C1
Autophagy-IN-C1 is a cinchona alkaloid derivative containing urea. Autophagy-IN-C1 not only induces apoptosis but also blocks autophagy in hepatocellular carcinoma (HCC) cells.
价 格:¥电议型 号:T38977产 地:中国大陆
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T38966PXS-4681A;PXS-4681APXS-4681A
PXS-4681A is a powerful, specific, and irreversible inhibitor of semicarbazide-sensitive amine oxidase (SSAO; VAP-1), with an oral activity and a Ki value of 37 nM. It exhibits exceptional selectivity towards related amine oxidases, ion channels, and seven-transmembrane domain receptors. Additionally, PXS-4681A demonstrates potent anti-inflammatory properties.
价 格:¥电议型 号:T38966产 地:中国大陆
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T38916Antibacterial agent 51;Antibacterial agent 51Antibacterial agent 51
Antibacterial agent 51 (example 45) is a potent antibacterial compound effective against E. coli strains NCTC 13351, M 50, and 7 MP, with MIC values of 4, 8, and 8 mcg/mL, respectively (WO2013030733A1).
价 格:¥电议型 号:T38916产 地:中国大陆
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T38886Antibacterial agent 61;Antibacterial agent 61Antibacterial agent 61
Antibacterial agent 61 (example 27) is a antibacterial agent.
价 格:¥电议型 号:T38886产 地:中国大陆
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T38865Antibacterial agent 41;Antibacterial agent 41Antibacterial agent 41
Antibacterial agent 41 (example 3) is a antibacterial agent.
价 格:¥电议型 号:T38865产 地:中国大陆
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T38641AP 811;AP 811AP 811
AP 811, a selective antagonist of the atrial natriuretic peptide clearance receptor (APN-CR, NPR3) with a K i value of 0.48 nM, exhibits remarkable selectivity for NPR3 over NPR1 by more than 20,000-fold. Moreover, AP 811 effectively eliminates ANP-induced pump stimulation.
价 格:¥电议型 号:T38641产 地:中国大陆
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T38392JAMI1001A;JAMI1001AJAMI1001A
JAMI1001A is a positive allosteric modulator of the AMPA receptor, effectively modulating the deactivation and desensitization of both flip and flop receptor isoforms.
价 格:¥电议型 号:T38392产 地:中国大陆
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T38160STING Agonist 1a;STING Agonist 1aSTING Agonist 1a
STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expression of IFN-β, IL-6, and chemokine (C-X-C motif) ligand 10 (CXCL10) in THP-1 cells, an effect that can be reversed by STING knockout or the STING inhibitor H-151 .
价 格:¥电议型 号:T38160产 地:中国大陆
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T37663Emamectin B1aEmamectin B1aEmamectin B-1a|||Emamectin B1a
Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.
价 格:¥电议型 号:T37663产 地:中国大陆
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T37610AT-121;化合物AT-121AT-121
AT-121 is a dual μ-opioid and neuropeptide receptor partial agonist (Kis 16.49 and 3.67 nM, respectively). It stimulates [35S]GTPγS binding to cell membranes expressing either μ-opioid receptors or neuropeptide receptors (EC50s of 19.6 and 34.7 nM, respectively.) AT-121 (0.003-0.03 mg/kg) reduced capsaicin-induced thermal anisocoria in a dose-dependent manner, but did not increase scratching activity in rhesus monkeys. In rhesus monkey drug self-administration tests, AT-121 at doses of 0.3 to 10
价 格:¥电议型 号:T37610产 地:中国大陆
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T37448UZH1a;UZH1aUZH1a
UZH1a is a potent and selective inhibitor of METTL3, exhibiting an IC50 of 280 nM. It serves as a tool for epitranscriptomic modulation of cellular processes and possesses antitumor activity. Additionally, UZH1a functions as a chemical probe for the study of METTL3[1].
价 格:¥电议型 号:T37448产 地:中国大陆
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T37173Bofutrelvir;福布特韦DC-402234|||MPro Inhibitor 11a|||FB2001;DC-402234|||MPro Inhibitor 11a|||FB2001
Bofutrelvir (FB2001) is a SARS-CoV-2 3CL protease inhibitor with antiviral activity for the study of novel coronavirus pneumonia (COVID-19) infections.
价 格:¥电议型 号:T37173产 地:中国大陆