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T4317PF 429242;化合物PF 429242PF 429242
PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rate of cholesterol synthesis in CHO cells (IC50 = 0.53 μM).
价 格:¥电议型 号:T4317产 地:中国大陆
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T4307PF-06840003;化合物PF06840003EOS200271|||PF 06840003;EOS200271|||PF 06840003
PF-06840003 (EOS200271) is a specific and oral active IDO-1 inhibitor.
价 格:¥电议型 号:T4307产 地:中国大陆
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T4285Crisaborole;克立硼罗AN-2728|||PF-06930164;克立硼罗|||AN-2728|||PF-06930164
Crisaborole (AN-2728) is a Phosphodiesterase 4 Inhibitor.
价 格:¥电议型 号:T4285产 地:中国大陆
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T4230PF-3758309 hydrochloride;化合物PF-3758309 hydrochloridePF-03758309 hydrochloride;PF-03758309 hydrochlor
PF-3758309 hydrochloride (PF-03758309 hydrochloride) , is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PF-3758309 hydrochloride binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation
价 格:¥电议型 号:T4230产 地:中国大陆
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T4221PF-06260933;化合物PF6260933PF-6260933|||PF 6260933|||PF6260933;PF-6260933|||PF 6260933|||PF6260933
PF-06260933 is a highly selective small-molecule MAP4K4 inhibitor with IC50s of 3.7 and 160 nM for kinase and cell, respectively.
价 格:¥电议型 号:T4221产 地:中国大陆
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T41275PF-04753299;化合物PF-04753299PF-04753299
PF-04753299 is a potent and selective inhibitor of UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC), demonstrating bactericidal effects against gonococcal isolates. It exhibits inhibitory activity against E. coli, P. aeruginosa, and K. pneumoniae, with minimum inhibitory concentration (MIC) 90 values of 2 μg/ml, 4 μg/ml, and 16 μg/ml, respectively. This compound is utilized in researching gram-negative bacterial infections [1].
价 格:¥电议型 号:T41275产 地:中国大陆
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T4090PF-06282999;化合物PF06282999PF-06282999
PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potentially useful for the treatment of cardiovascular diseases.
价 格:¥电议型 号:T4090产 地:中国大陆
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T4073Kaempferol-7-O-β-D-glucopyranoside;山奈酚-7-O-葡萄糖苷Kaempferol-7-O-D-glucopyranoside;山奈酚-7-O-葡萄糖苷|||Kaemp
Kaempferol-7-O-β-D-glucopyranoside (Kaempferol-7-O-D-glucopyranoside) , a novel supercoolant could be used to sub-zero non-freezing rat heart preservation.
价 格:¥电议型 号:T4073产 地:中国大陆
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T40638Kaempferol-3-O-(2’’-O-β-D-glucopyl)-β-D-rutinoside;Kaempferol-3-O-(2’’-O-β-D-glucopyl)-β-D-rutinosid
Kaempferol-3-O-(2´´-O-β-D-glucopyl)-β-D-rutinoside is a naturally occurring glycoside present in the seeds of Camellia oleifera.
价 格:¥电议型 号:T40638产 地:中国大陆
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T40610Kaempferol 3-O-(2′′-O-α-rhamnosyl-6′′-O-malonyl-β-glucoside);Kaempferol 3-O-(2′′-O-α-rhamnosyl-6′′-O
Kaempferol 3-O-(2′′-O-α-rhamnosyl-6′′-O-malonyl-β-glucoside) is a natural compound that belongs to the flavonoid glycosides. It can be isolated from the petals of Clitoria ternatea cv. Double Blue.
价 格:¥电议型 号:T40610产 地:中国大陆
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T40120FNC-TP;FNC-TPFNC-TP
FNC-TP, the intracellular active form of FNC, is a potent nucleoside reverse transcriptase inhibitor (NRTI) with broad-spectrum antiviral activity against HIV, HBV, and HCV.
价 格:¥电议型 号:T40120产 地:中国大陆
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T3S1390Leucoside;堪非醇3-O-桑布双糖苷Kaempferol 3-sambubioside|||Kaempferol 3-O-sambubioside;堪非醇3-O-桑布双糖苷|||Kaempfe
Leucoside (Kaempferol 3-sambubioside) is a naturally occuring flavonol bioside with many biological activities.
价 格:¥电议型 号:T3S1390产 地:中国大陆
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T3973PF-CBP1;化合物PF-CBP1PF-CBP1
PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP). It inhibits CREBBP (IC50: 125 nM) and p300 bromodomains (IC50: 363 nM).
价 格:¥电议型 号:T3973产 地:中国大陆
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T39617Propargyl-PEG5-PFP ester;Propargyl-PEG5-PFP esterPropargyl-PEG5-PFP ester;Propargyl-PEG5-PFP ester
Propargyl-PEG5-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39617产 地:中国大陆
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T39616Propargyl-PEG3-PFP ester;Propargyl-PEG3-PFP esterPropargyl-PEG3-PFP ester;Propargyl-PEG3-PFP ester
Propargyl-PEG3-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39616产 地:中国大陆
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T39539Cyclooctyne-O-amido-PEG2-PFP ester;Cyclooctyne-O-amido-PEG2-PFP esterCyclooctyne-O-amido-PEG2-PFP es
Cyclooctyne-O-amido-PEG2-PFP ester is a two-unit polyethylene glycol (PEG) linker incorporated into antibody-drug conjugates (ADCs). It is a non-cleavable linker utilized in the synthesis of ADCs.
价 格:¥电议型 号:T39539产 地:中国大陆
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T39538BCOT-PEF3-OPFP;BCOT-PEF3-OPFPBCOT-PEF3-OPFP;BCOT-PEF3-OPFP
BCOT-PEF3-OPFP is a cleavable linker vital in ADC synthesis. BCOT-PEF3-OPFP joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格:¥电议型 号:T39538产 地:中国大陆
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T39536Cyclooctyne-O-amido-PEG3-PFP ester;Cyclooctyne-O-amido-PEG3-PFP esterCyclooctyne-O-amido-PEG3-PFP es
Cyclooctyne-O-amido-PEG3-PFP ester is a non-cleavable 3-unit PEG linker employed in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T39536产 地:中国大陆
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T39534Mal-amido-PEG3-C1-PFP ester;Mal-amido-PEG3-C1-PFP esterMal-amido-PEG3-C1-PFP ester;Mal-amido-PEG3-C1
Mal-amido-PEG3-C1-PFP ester, a non-cleavable 3 unit PEG ADC linker, finds application in the synthesis of antibody-drug conjugates (ADCs).´
价 格:¥电议型 号:T39534产 地:中国大陆
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T39518PFB-FDGlu;化合物 PFB-FDGluPFB-FDGlu
PFB-FDGlu is a lysosomal Glucocerebrosidase (GCase) substrate with cell-permeable specificity that is cleaved to produce fluorescein.PFB-FDGlu is often used in conjunction with a flow cytometer to measure GCase activity in living cells on an individual cell basis.
价 格:¥电议型 号:T39518产 地:中国大陆