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T70753PF00349412;化合物 PF00349412PF00349412
PF00349412 is a selective inhibitor of protozoan protein N-?myristoyltransferases. Inhibition of N-?myristoyltransferase has been validated pre-?clin. as a target for the treatment of fungal and trypanosome infections, using species-?specific inhibitors.
价 格:¥电议型 号:T70753产 地:中国大陆
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T70751PF-719 free base;化合物 PF-719 free basePF-719 free base
PF-719 is a potent, selective Pyk2 inhibitor with IC50 of 17 nM.
价 格:¥电议型 号:T70751产 地:中国大陆
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T70712PF-06412154 HCl;化合物 PF-06412154 HClPF-06412154 HCl
PF-06412154 HCl is a glucagon receptor antagonist.
价 格:¥电议型 号:T70712产 地:中国大陆
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T70665PF-06284674;化合物 PF-06284674PF-06284674
PF-06284674 is a cell permeable, potent and selective M2 isoform of pyruvate kinase (PKM2) activator.
价 格:¥电议型 号:T70665产 地:中国大陆
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T70591PF1070A;化合物 PF1070APF1070A
PF1070A is a natural cyclic tetrapeptide HDAC Inhibitor through the inhibition of PfHDAC1 catalytic activity, potently inducing the synthesis of metallothionein.
价 格:¥电议型 号:T70591产 地:中国大陆
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T7040Angiotensin II human;血管紧张素ⅡDRVYIHPF|||Angiotensin II|||Hypertensin II|||Ang II;DRVYIHPF|||Angiotensi
Angiotensin II human (Ang II) is a biologically active peptide, a vasoconstrictor. Angiotensin II interacts with AT1R and AT2R to regulate blood pressure, stimulate sympathetic nerves, and increase aldosterone biosynthesis and renal activity in humans.
价 格:¥电议型 号:T7040产 地:中国大陆
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T70393PF-303;化合物 PF-303PF-303
PF-303 is a covalent-reversible BTK inhibitor. Inhibitors of Bruton´s tyrosine kinase (BTK) possess much promise for the treatment of oncologic and autoimmune indications.
价 格:¥电议型 号:T70393产 地:中国大陆
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T70379PF-04479745 tartrate;化合物 PF-04479745 tartratePF-04479745 tartrate
PF-04479745, also known as PF-4479745, is a potent and selective 5-HT2C agonist (EC50 = 10 nM). PF-4479745 displayed robust pharmacology in a preclinical canine model of stress urinary incontinence (SUI) and no measurable functional agonism at the key selectivity targets 5-HT2A and 5-HT2B in relevant tissue-based assay systems.
价 格:¥电议型 号:T70379产 地:中国大陆
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T70370PF-06658607;化合物 PF-06658607PF-06658607
PF-06658607 is an alkynylated irreversible Brutons tyrosine kinase (BTK) inhibitor.
价 格:¥电议型 号:T70370产 地:中国大陆
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T70369PF-06672131;化合物 PF-06672131PF-06672131
PF-06672131 is a selective EGFR kinase inhibitor.
价 格:¥电议型 号:T70369产 地:中国大陆
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T70366PF-06663195;化合物 PF-06663195PF-06663195
PF-06663195 is a potent inhibitor of β-site amyloid precursor protein (APP) Cleaving Enzyme 1 (BACE1, β-Secretase 1).
价 格:¥电议型 号:T70366产 地:中国大陆
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T70363PF-06371900;化合物 PF-06371900PF-06371900
PF-06371900 is a potent and highly selective inhibitor of leucine-rich repeat kinase 2 (LRRK2).
价 格:¥电议型 号:T70363产 地:中国大陆
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T70299PF-05214030;化合物 PF-05214030PF-05214030
PF-05214030 is a novel potent TRPV4 antagonist (hTRPV4 IC50 4nM; rTRPV4 IC50 27nM).
价 格:¥电议型 号:T70299产 地:中国大陆
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T70160PF-06427878;化合物 PF-06427878PF-06427878
PF-06427878 is an orally active, potent and selective diacylglycerol acyltransferase 2 inhibitor.
价 格:¥电议型 号:T70160产 地:中国大陆
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T70060PF-06463922 acetate;化合物 PF-06463922 acetatePF-06463922 acetate
PF-06463922 acetate is a potent, selective brain-penetrable inhibitor of both anaplastic lymphoma kinase (ALK) and c-ros Oncogene 1 (ROS1) with strong activity against all known ALK and ROS1 mutants identified in patients with crizotinib-resistant disease. PF-06463922 is in clinical trials for the treatment of non–small cell lung cancer (NSCLC).
价 格:¥电议型 号:T70060产 地:中国大陆
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T70042PF-06748962;化合物 PF-06748962PF-06748962
PF-06748962 is a potent and selective lactam-based prostaglandin EP3 receptor antagonist.
价 格:¥电议型 号:T70042产 地:中国大陆
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T6S1294Nicotiflorin;山奈酚-3-O-芸香糖苷Nictoflorin|||Kaempferol-3-O-Rutinoside|||Nicotifloroside;Nictoflorin|||Kae
1. Nicotiflorin (Kaempferol-3-O-Rutinoside) has potential therapeutic effects on cerebral ischemic illness. 2. Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model rats.
价 格:¥电议型 号:T6S1294产 地:中国大陆
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T6S1101Astragalin;紫云英苷Kaempferol 3-D-glucoside|||Kaempferol 3-O-glucoside|||kaempferol-3-glucoside|||3-Gluc
Astragalin (Kaempferol 3-O-glucoside) is a biologically active natural flavonoid. It has a variety of pharmacological properties, including antioxidant, anti-inflammatory, anti-cancer, neuroprotective, and cardioprotective properties.
价 格:¥电议型 号:T6S1101产 地:中国大陆
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T6S0840Engeletin;黄杞苷Dihydrokaempferol 3-rhamnoside;Dihydrokaempferol 3-rhamnoside|||黄杞苷
1. Engeletin (Dihydrokaempferol 3-rhamnoside) may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engeletin inhibits a recombinant human aldose reductase (IC5 value=1.16 microM).
价 格:¥电议型 号:T6S0840产 地:中国大陆
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T69973PF-04363467 HCl;化合物 PF-04363467 HClPF-04363467 HCl
PF-04363467 HCl is a selective dopamine D3/D2 receptor antagonist.
价 格:¥电议型 号:T69973产 地:中国大陆