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T6043PF-3845PF-3845,PF3845,PF 3845
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.
价 格:¥电议型 号:T6043产 地:美洲
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T6085PF-543PF-543,PF543,PF 543
PF-543, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
价 格:¥电议型 号:T6085产 地:美洲
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T6127Rucaparib PhosphateRucaparib Phosphate,PF-01367338 phosphate,AG-014699 phosphate
Rucaparib is an inhibitor of PARP (Ki: 1.4 nM for PARP1) that is used in clinical therapy to sensitize cancer cells to chemotherapy.
价 格:¥电议型 号:T6127产 地:美洲
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T6177PF-562271 besylatePF-562271 besylate,PF-00562271 Besylate,
PF-562271 (besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
价 格:¥电议型 号:T6177产 地:美洲
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T6181UPF 1069UPF 1069
UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.
价 格:¥电议型 号:T6181产 地:美洲
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T6222PFI-1PFI-1,PFI1,PFI 1
PFI-1, a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.
价 格:¥电议型 号:T6222产 地:美洲
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T6251PF-04691502PF-04691502,PF04691502,PF 04691502
PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.
价 格:¥电议型 号:T6251产 地:美洲
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T8849PF-9601N;化合物PF9601Nexcitotoxicity|||PF-9601N|||neurodegenerative diseases|||MAO|||PF9601N|||Monoamin
PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.
价 格:¥电议型 号:T8849产 地:中国大陆
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T8840PF-543 hydrochloride;化合物PF-543PF-543;PF-543
PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
价 格:¥电议型 号:T8840产 地:中国大陆
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T8767PfDHODH-IN-2;化合物PfDHODH-IN-2PfDHODH-IN-2
PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor . It is used an antimalarial agent and can be used for the research of malaria
价 格:¥电议型 号:T8767产 地:中国大陆
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T8711PF-05186462;化合物PF-05186462PF-05150122;PF-05150122
PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.
价 格:¥电议型 号:T8711产 地:中国大陆
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T8645PF-06446846;化合物PF-06446846PF-06446846
PF 06446846 is a potent and selective PCSK9 inhibitor
价 格:¥电议型 号:T8645产 地:中国大陆
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T8560Angiotensin II human acetate血管紧张素IIAng II acetate|||DRVYIHPF acetate|||Angiotensin II acetate|||血管紧张
Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.
价 格:¥电议型 号:T8560产 地:中国大陆
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T8463PF-06873600;化合物PF-06873600PF-06873600
PF-06873600 is a selective and orally bioavailable cyclin-dependent kinase (CDK) inhibitor(CDK2, CDK4 and CDK6 with Ki of 0.09 nM, 0.13 nM and 0.16 nM, respectively), has potential antineoplastic activity.
价 格:¥电议型 号:T8463产 地:中国大陆
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T8399Crizotinib hydrochloride;克里唑替尼盐酸PF-02341066 hydrochloride;克里唑替尼盐酸|||PF-02341066 hydrochloride
Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)
价 格:¥电议型 号:T8399产 地:中国大陆
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T832656-Hydroxykaempferol 7-O-β-glucopyranoside;化合物 6-Hydroxykaempferol 7-O-β-glucopyranoside6-Hydroxykaem
6-Hydroxykaempferol 7-O-β-glucopyranoside (compound 5), a flavonol, has been isolated from the plant Tagetes minuta, commonly known as wild marigold [1].
价 格:¥电议型 号:T83265产 地:中国大陆
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T82696Cofetuzumab;化合物 CofetuzumabPF-06523435|||hu24;PF-06523435|||hu24
Cofetuzumab (PF-06523435) is a humanized IgG1-κ monoclonal antibody designed to target PTK7, with Chinese Hamster Ovary (CHO) cells acting as the primary expression system [1].
价 格:¥电议型 号:T82696产 地:中国大陆
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T82673CPF-7;化合物 CPF-7Caerulein precursor fragment;Caerulein precursor fragment
CPF-7 (Caerulein precursor fragment), an insulinotropic peptide, promotes insulin secretion and drives epithelial-mesenchymal transition via Snai1 upregulation in PANC-1 ductal cells. Moreover, it induces exocrine plasticity through Ngn3 upregulation, with applications in type 2 diabetes research [1] [2].
价 格:¥电议型 号:T82673产 地:中国大陆
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T8202Kaempferol 3-O-gentiobioside;山柰酚 3-龙胆双糖苷Kaempferol 3-gentiobioside;Kaempferol 3-gentiobioside|||山柰酚
Kaempferol 3-O-gentiobioside is a flavonoid isolated from C. alata leaves with antidiabetic activity. It possesses activity against α-glucosidase and displays a carbohydrate enzyme inhibitory effect (IC50: 50 μM).
价 格:¥电议型 号:T8202产 地:中国大陆
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T81992Kaempferol 3,7-bis(α-L-rhamnose-D-glucose);化合物 Kaempferol 3,7-bis(α-L-rhamnose-D-glucose)Kaempferol
Kaempferol 3,7-bis(α-L-rhamnose-D-glucose) (compound 1), a flavonoid glycoside, is present in Euonymus fortunei.
价 格:¥电议型 号:T81992产 地:中国大陆