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产品数:86101
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T16484PF-05180999PF-05180999
PF-05180999 is an inhibitor of phosphodiesterase 2A (IC50: 1.6 nM).
价 格:¥电议型 号:T16484产 地:美洲
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T16486PF-05231023PF-05231023
PF-05231023 is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist. It is also suitable for development as a potential treatment for T2DM.
价 格:¥电议型 号:T16486产 地:美洲
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T16490PF-06380101PF-06380101,Aur0101,Auristatin-0101
PF-06380101 is an auristatin microtubule inhibitor and is a cytotoxic Dolastatin 10 analogue. When compared to other synthetic auristatin analogues that are used in the preparation of ADCs, PF-06380101 displays excellent potencies in tumor cell proliferat
价 格:¥电议型 号:T16490产 地:美洲
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T16491PF-06446846 hydrochloridePF-06446846 hydrochloride
PF-06446846 hydrochloride suppresses PCSK9 by inducing the ribosome to stall around codon 34. PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9.
价 格:¥电议型 号:T16491产 地:美洲
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T16492PF-06459988PF-06459988
PF-06459988 is an irreversible T790M-Containing EGFR Mutants inhibitor.
价 格:¥电议型 号:T16492产 地:美洲
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T16494PF-06471553PF-06471553
PF-06471553 is an effective and selective inhibitor of monoacylglycerol acyltransferase 3 (IC50: 92 nM).
价 格:¥电议型 号:T16494产 地:美洲
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T16495PF-06747711PF-06747711
PF-06747711 is an effective and selective retinoic acid receptor-related orphan C2 inverse agonist (IC50: 4.1 nM). PF-06747711 also has anti-skin inflammatory activity.
价 格:¥电议型 号:T16495产 地:美洲
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T16497PF 1022APF 1022A
PF 1022A is an N-methylated cyclooctadepsipeptides with strong anthelmintic properties. It also acts as an ionosphere.
价 格:¥电议型 号:T16497产 地:美洲
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T16499MardepodectMardepodect,PF-2545920,
Mardepodect is an effective and selective PDE10A inhibitor (IC50: 0.37 nM). Mardepodect has >1000-fold selectivity over other PDEs. Mardepodect can cross the blood-brain barrier.
价 格:¥电议型 号:T16499产 地:美洲
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T16501PF-3644022PF-3644022
PF-3644022 is an effective, selective, and ATP-competitive MAPKAPK2 (MK2) inhibitor (IC50: 5.2 nM and a Ki of 3 nM). PF-3644022 potently inhibits TNFα production and has an anti-inflammatory effect. PF-3644022 also inhibits MK3 and p38 regulated/activated
价 格:¥电议型 号:T16501产 地:美洲
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T16503PF-4191834PF-4191834,PF-04191834,
PF-4191834 is an orally active, noniron chelating, and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) (IC50=229 nM). PF-4191834 shows ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX and displays no activity toward the cyclooxygenase enzymes. PF-
价 格:¥电议型 号:T16503产 地:美洲
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T16506PF-4878691PF-4878691,3M-852A,
PF-4878691 is an effective and selective Toll-like receptor 7 agonists modelled. It is used to dissociate its antiviral and inflammatory activities.
价 格:¥电议型 号:T16506产 地:美洲
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T16508PF-5190457PF-5190457
PF-5190457 is an effective and selective ghrelin receptor inverse agonist (pKi: 8.36).
价 格:¥电议型 号:T16508产 地:美洲
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T16510PF-915275PF-915275
The dose-dependent effect of PF-915275 on the conversion of cortisone to cortisol in primary human and monkey hepatocytes (EC50: 20 and 100 nM, respectively). PF-915275 is an effective and selective human 11β-hydroxysteroid dehydrogenase type 1 inhibitor
价 格:¥电议型 号:T16510产 地:美洲
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T16512PFE-360PFE-360,PF-06685360,
PFE-360 is an effective, selective, brain penetrated leucine-rich repeat kinase 2 (IC50: 2.3 nM in vivo).
价 格:¥电议型 号:T16512产 地:美洲
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T16514PF 04531083PF 04531083
PF 04531083 is a selective NaV1.8 blocker. It is used for the research of neuropathic/inflammatory pain.
价 格:¥电议型 号:T16514产 地:美洲
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T16515PF 750PF 750
PF 750 is a selective and covalent fatty acid amide hydrolase inhibitor, It shows IC50s varied from 16.2-595 nM in different pre-incubation times.
价 格:¥电议型 号:T16515产 地:美洲
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T16845SarolanerSarolaner,PF-6450567,
Sarolaner is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).
价 格:¥电议型 号:T16845产 地:美洲
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T19378IpfencarbazoneIpfencarbazone
Ipfencarbazone herbicide agent, is a substance being developed for the control of weeds such as watergrass in rice.
价 格:¥电议型 号:T19378产 地:美洲
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T1970GedatolisibGedatolisib,PF-05212384,PKI-587
Gedatolisib is a highly effective dual inhibitor targeting the PI3Kα/γ (IC50: 0.4/5.4 nM)and mTOR (IC50: 1.6 nM) in the PI3K/mTOR signaling pathway.
价 格:¥电议型 号:T1970产 地:美洲