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T69948PF-06862309;化合物 PF-06862309PF-06862309
PF-06862309 is a PI3K inhibitor
价 格:¥电议型 号:T69948产 地:中国大陆
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T69750p-MPPF dihydrochloride;化合物 p-MPPF dihydrochloridep-MPPF dihydrochloride
p-MPPF dihydrochloride is a selective 5-ht1a serotonin receptor antagonist
价 格:¥电议型 号:T69750产 地:中国大陆
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T69526PF-07258669;化合物 PF-07258669PF-07258669
PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.
价 格:¥电议型 号:T69526产 地:中国大陆
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T6939PFI-3;化合物PFI-3PFI 3;PFI 3
PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.
价 格:¥电议型 号:T6939产 地:中国大陆
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T6938PF-4989216;化合物PF-4989216PF 4989216;PF 4989216
PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.
价 格:¥电议型 号:T6938产 地:中国大陆
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T6937PF-04620110;化合物PF-04620110PF04620110|||PF 04620110;PF04620110|||PF 04620110
PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
价 格:¥电议型 号:T6937产 地:中国大陆
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T6936PF-03814735化合物PF-03814735PF03814735|||inhibit|||PF-03814735
PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.
价 格:¥电议型 号:T6936产 地:中国大陆
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T6935Nirogacestat;化合物PF03084014PF-03084014|||PF-3084014|||PF03084014|||PF 03084014;PF-03084014|||PF-30840
Nirogacestat (PF 03084014) is a specific γ-secretase inhibitor (IC50: 6.2 nM, in a cell-free assay).
价 格:¥电议型 号:T6935产 地:中国大陆
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T6914Oclacitinib maleate;奥拉替尼马来酸盐PF-03394197 maleate|||PF-03394197;PF-03394197 maleate|||奥拉替尼马来酸盐|||PF-03
Oclacitinib maleate (PF-03394197 maleate) is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 38 non-JAK kinases.
价 格:¥电议型 号:T6914产 地:中国大陆
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T68557PF-376304;化合物 PF-376304PF-376304
PF-376304 is a nonspecific PI3K inhibitor under development for anti-inflammatory indications. Phosphoinositide 3-kinase (PI3K) is an enzyme fundamental to the regulation of various metabolic processes.
价 格:¥电议型 号:T68557产 地:中国大陆
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T68546PF-00337210;化合物 PF-00337210PF-00337210
PF-00337210 is an orally available ATP-competitive inhibitor of the vascular endothelial growth factor receptor type 2 (VEGFR2), with potential anti-angiogenesis and antineoplastic activities. Upon administration, the VEGFR2 tyrosine kinase inhibitor PF-00337210 selectively binds to VEGFR2 and prevents its phosphorylation which may result in an inhibition of migration, proliferation and survival of endothelial cells, microvessel formation, the inhibition of tumor cell proliferation, and may even
价 格:¥电议型 号:T68546产 地:中国大陆
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T68522PF-446687;化合物 PF-446687PF-446687
PF-446687 is a highly selective MC4 receptor (MC4R) agonist.
价 格:¥电议型 号:T68522产 地:中国大陆
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T68490CMPF;化合物CMPFCMPF
CMPF is a microtubule protein inhibitor that can be used to study tumors.
价 格:¥电议型 号:T68490产 地:中国大陆
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T68426Dipfluzine;化合物 DipfluzineDipfluzine
Dipfluzine is a diphenylpiperazine calcium channel blocker with poor solubility.
价 格:¥电议型 号:T68426产 地:中国大陆
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T68265PF-04445597;化合物 PF-04445597PF-04445597
PF-04445597 is a potent, orally bioavailable inhibitor of cholesteryl ester transfer protein (CETP).
价 格:¥电议型 号:T68265产 地:中国大陆
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T6826Emricasan;恩利卡生PF 03491390|||IDN-6556;PF 03491390|||恩利卡生|||IDN-6556
Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties. Emricasan has anti-inflammatory and anti-apoptotic activity and can be used in the treatment of infections and liver failure, etc. Emricasan also inhibits Zika virus infections.
价 格:¥电议型 号:T6826产 地:中国大陆
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T68244PF-04279405;化合物 PF-04279405PF-04279405
PF-04279405 is a potent and selective glucokinase activator.
价 格:¥电议型 号:T68244产 地:中国大陆
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T68125LPD 0299685;化合物PD0299685PF-299685|||PD-299,685;PF-299685|||PD-299,685
PD 0299685 is a potent α2δ ligand of the Ca2+ channel for the treatment of interstitial cystitis.
价 格:¥电议型 号:T68125L产 地:中国大陆
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T67874PFKFB3-IN-2;化合物PFKFB3-IN-2PFKFB3-IN-2
PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor. Anti-sense treatment against PFKFB3 was shown to reduce tumor growth rate in vivo.
价 格:¥电议型 号:T67874产 地:中国大陆