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产品数：86101
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T6934PexmetinibAutophagy,p38 MAPK,ARRY 614,Pexmetinib,Inhibitor,ARRY614,inhibit
Pexmetinib (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. Phase 1.
价 格：￥电议型 号：T6934产 地：中国大陆
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TQ0079GNE-495MAPK Kinase Kinase Kinase,MAP4K,inhibit,GNE-495,GNE 495,GNE495,Inhibitor
GNE-495 is a potent and specific MAP4K4 inhibitor (IC50: 3.7 nM).
价 格：￥电议型 号：TQ0079产 地：中国大陆
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TN1445BisabolangeloneBisabolangelone,Inhibitor,inhibit,p38 MAPK
Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-κB signaling.
价 格：￥电议型 号：TN1445产 地：中国大陆
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T12871Talmapimodcytotoxicity,multiple,inhibit,tumor,SCIO 469,SCIO469,cells,Hsp27,Inhibitor,phosphorylation
Talmapimod is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs.
价 格：￥电议型 号：T12871产 地：中国大陆
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T7323BCI-215specificity,Phosphatase,DUSP-MKP,inhibit,Inhibitor,MAPK,BCI-215,BCI215,BCI 215,dual
BCI-215 causes selective cancer cell cytotoxicity in part through non-redox-mediated activation of MAPK signaling
价 格：￥电议型 号：T7323产 地：中国大陆
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T7030anemarsaponin BNF-κB,Nuclear factor-kappaB,COX,MAP2K,anemarsaponin B,Mitogen-activated protein kinas
Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B can inhibit PAF-induced rabbit platelet aggregation in vitro.
价 格：￥电议型 号：T7030产 地：中国大陆
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T6665Sertaconazole nitrateCOX-2,Inhibitor,inhibit,Sertaconazole nitrate,MCF-7,HaCaT,Candida,HeLa,p38 MAPK
Sertaconazole nitrate, a topical broad-spectrum antifungal, is developed to supply an additional agent for the treatment of superficial cutaneous and mucosal infections.
价 格：￥电议型 号：T6665产 地：中国大陆
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T12347p38-α MAPK-IN-1Inhibitor,inhibit,p-38-α MAPK-IN-1,Autophagy,p38α MAPKIN1,p38 MAPK,p38 α MAPK IN 1
p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor with IC50 of 2300 nM and 5500 nM in EFC displacement assay and HTRF assay,respectively.
价 格：￥电议型 号：T12347产 地：中国大陆
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T6440CGP 57380CGP-57380,CGP 57380,Mitogen activated protein kinase interacting kinase,Inhibitor,MAPK inte
CGP 57380 is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases.
价 格：￥电议型 号：T6440产 地：中国大陆
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T9377ASK1-IN-2colitis,ulcerative,signal-regulating,ASK1 IN 2,ASK1IN2,inhibit,MAP kinase kinase kinase, ME
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can potentially be used as a therapeutic strategy for ulcerative colitis[1].
价 格：￥电议型 号：T9377产 地：中国大陆
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TN1721Gypenoside LMAPK,Extracellular signal regulated kinases,NF-κB,Nuclear factor-κB,saponin,anti-tumor,N
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory activity.
价 格：￥电议型 号：TN1721产 地：中国大陆
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T9470HPK1-IN-7HPK1 IN 7,MC38,Inhibitor,PD1,HPK1IN7,tumor,model,oral,selectivity,HPK-1-IN-7,MAP4K,inhibit,
HPK1-IN-7 is an orally active HPK1 inhibitor. It shows selectivity against IRAK4 (59 nM) and GLK (140 nM).
价 格：￥电议型 号：T9470产 地：中国大陆
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T9321zapnometinibantiviral,virus,MAPKK,zapnometinib,Influenza Virus,ATR002,Bacterial,CI-1040,Inhibitor,PD
zapnometinib is a MEK inhibitor.
价 格：￥电议型 号：T9321产 地：中国大陆
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T6785BI-847325BI 847325,inhibit,Apoptosis,MEK,MAPKK,MAP2K,Inhibitor,Aurora Kinase,Mitogen-activated prote
BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.
价 格：￥电议型 号：T6785产 地：中国大陆
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T9034MK2-IN-3MAPK activated protein kinase 2,Mitogen-activated protein kinase activated protein kinase 2,
MK2-IN-3 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis
价 格：￥电议型 号：T9034产 地：中国大陆
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T6911NSC-87877 disodiumApoptosis,Neuroblastoma,inhibit,Inhibitor,NSC 87877 disodium,PPAR,p53,Phosphatase,
NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
价 格：￥电议型 号：T6911产 地：中国大陆
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T6971Ro 5126766MAPKK,CH 5126766,MEK,Ro 5126766,Raf kinases,Raf,Mitogen-activated protein kinase kinase,in
RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 nM, and 160 nM for BRAF V600E, BRAF, CRAF, and MEK1, respectively. Phase 1.
价 格：￥电议型 号：T6971产 地：中国大陆
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TL0004FERULIC ACID METHYL ESTERInhibitor,inhibit,p38 MAPK,Autophagy,FERULIC ACID METHYL ESTER
Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis). This naturally-occurring phenolic has antioxidant activities that provide protection against inflammation and cancer. Ferulic acid methyl ester is a lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes.
价 格：￥电议型 号：TL0004产 地：中国大陆
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T6692TAK-733inhibit,Inhibitor,TAK-733,MAP2K,MAPKK,MEK,Mitogen-activated protein kinase kinase
MEK Inhibitor TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
价 格：￥电议型 号：T6692产 地：中国大陆
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T7926CarmoisineInhibitor,Artificial,Acid Red-14,E122,colorant,E-122,Carmoisine,inhibit,MAPK8,proinflammat
Azo Rubine is a food dye Azorubine and is used for the purposes where food is heat-treated after fermentation.
价 格：￥电议型 号：T7926产 地：中国大陆
