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T61091p38-α MAPK-IN-4;化合物 p38-α MAPK-IN-4p38-α MAPK-IN-4
p38-α MAPK-IN-4 (Compound 69) is a selective inhibitor of p38α MAPK, demonstrating potent inhibition with an IC50 of 1.5 μM. It effectively and swiftly mitigates the onset of mechanical allodynia (MA) in vivo [1].
价 格:¥电议型 号:T61091产 地:中国大陆
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T6089Neflamapimod化合物NeflamapimodVX-745
Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.
价 格:¥电议型 号:T6089产 地:中国大陆
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T60754MAPK-IN-1;化合物 MAPK-IN-1MAPK-IN-1
MAPK-IN-1 (Compound 2) is an inhibitor of MAPK signaling pathway with anti-neuroinflammatory and neuroprotective activity that can be used for the research of Alzheimer´s disease. MAPK-IN-1 inhibits AChE with an IC 50 of 23.84 μM [1].
价 格:¥电议型 号:T60754产 地:中国大陆
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T60509Maprotiline;化合物 MaprotilineMaprotiline
Maprotiline inhibits cell proliferation and metastasis with anticancer effects. Maprotiline induces apoptosis in cancer cells by targeting ERK signaling pathway and CRABP1. Maprotiline is a highly selective norepinephrine reuptake blocker with potent antidepressant properties. [1][2].
价 格:¥电议型 号:T60509产 地:中国大陆
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T40622Mapenterol hydrochloride;马喷特罗盐酸盐Mapenterol hydrochloride
Mapenterol hydrochloride is an agonist of β2-adrenergic receptor.
价 格:¥电议型 号:T40622产 地:中国大陆
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T40454DMAPP;DMAPPDimethylallyl diphosphate;Dimethylallyl diphosphate
DMAPP, also known as Dimethylallyl pyrophosphate, is an isoprenoid precursor found in all life forms. It serves as an isomer of isopentenyl pyrophosphate (IPP).
价 格:¥电议型 号:T40454产 地:中国大陆
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T3S0462Rehmapicroside;地黄苦苷Rehmapicroside
Rehmapicroside is a natural product of Rehmannia, Scrophulariaceae. The catalog number is T3S0462 and the CAS number is 104056-82-8. Rehmapicroside can be used as a reference standard.
价 格:¥电议型 号:T3S0462产 地:中国大陆
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T39172SMAP-29;SMAP-29SMAP-29
SMAP-29 is a broad spectrum antibacterial and antifungal α-helical cathelicidin-derived peptide with strong potential as an antiinfective agent. It effectively permeabilizes bacterial membranes and induces significant alterations in the surface morphology of susceptible microorganisms.
价 格:¥电议型 号:T39172产 地:中国大陆
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T3915817-DMAP-GA;17-DMAP-GA17-DMAP-GA
17-DMAP-GA, a Geldanamycin analogue, acts as an HSP90 inhibitor, leading to cell cycle abnormalities.
价 格:¥电议型 号:T39158产 地:中国大陆
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T38796LMBP MAPK Substrate acetate;化合物MBP MAPK Substrate acetateMBP MAPK Substrate acetate(138028-00-9 free
MBP MAPK Substrate acetate can be used as an exogenous substrate for MAPK.
价 格:¥电议型 号:T38796L产 地:中国大陆
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T38796MBP MAPK Substrate;MBP MAPK SubstrateMBP MAPK Substrate
MBP MAPK Substrate is used as an exogenous substrate for MAPK.
价 格:¥电议型 号:T38796产 地:中国大陆
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T38570DMAPP triammonium;DMAPP三铵盐Dimethylallyl diphosphate triammonium|||Dimethylallyl Pyrophosphate triamm
DMAPP triammonium (Dimethylallyl diphosphate triammonium) is one of the prerequisite substances for an isoprenoid involved in the mevalonate (MVA) pathway, which can be used in the study of metabolism-related diseases.
价 格:¥电议型 号:T38570产 地:中国大陆
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T37056D-erythro-MAPPD-erythro-MAPPD erythro MAPP|||DerythroMAPP
D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 μM) as well as the serine/threonine protein phosphatase CAPP at concentrations up to 10 μM. D-erythro-MAPP increases intracellular ceramide levels, induces cell cycle arrest at the G0/G1 phase, and inhibits growth of HL-60 promyelocytic leukemia cells in a time- and concentration-dependent manner.
价 格:¥电议型 号:T37056产 地:中国大陆
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T36303Psammaplin A;Psammaplin APsammaplin A
Psammaplin A, a marine metabolite, functions as a robust inhibitor of HDAC and DNA methyltransferases, displaying notable potency and selectivity as a DAC1 inhibitor, with an IC50 value of 0.9 nM. It exhibits antimicrobial effects against Gram-positive bacteria and inhibits both DNA synthesis and DNA gyrase activity, also demonstrating antitumor activity[1][2].
价 格:¥电议型 号:T36303产 地:中国大陆
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T36011p38 MAP Kinase Inhibitor IV;p38 MAPK Inhibitor IVp38 MAPK Inhibitor IV;p38 MAPK Inhibitor IV
p38 MAPK inhibitor IV is an ATP-competitive inhibitor of p38 MAP kinases with IC50 values of 0.13, 0.55, 5.47, and 8.63 μM for p38α, p38β, p38x, and p38δ, respectively, in vitro.[1] It also inhibits LPS-induced TNF-α and IL-1β cytokine production (IC50s = 22 and 44 nM, respectively) in human peripheral blood mononuclear cells.
价 格:¥电议型 号:T36011产 地:中国大陆
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T36010p38 MAPK Inhibitor;化合物p38 MAPK抑制剂p38 MAPK Inhibitor
p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.
价 格:¥电议型 号:T36010产 地:中国大陆
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T35593Semapimod tetrahydrochloride;塞马莫德盐酸盐CPSI-2364 tetrahydrochloride;CPSI-2364 tetrahydrochloride
Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) is a synthetic ornithine mitogen-activated protein kinase blocker and pro-inflammatory cytokine production inhibitor that interferes with macrophage and microglia function. Sematimod tetrahydrochloride inhibits TLR4 signaling, TNF-α, IL-1β, and IL-6, and is used in the study of Crohn´s disease and other inflammatory conditions.
价 格:¥电议型 号:T35593产 地:中国大陆
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T35420(S)-p38 MAPK Inhibitor III;(S)-p38 MAPK Inhibitor III(S)-p38 MAPK Inhibitor III;(S)-p38 MAPK Inhibit
(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 μM, respectively).
价 格:¥电议型 号:T35420产 地:中国大陆
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T34799Telmapitant;化合物 T34799Telmapitant
Telmapitant is an antagonist of the neurokinin NK1 receptor.
价 格:¥电议型 号:T34799产 地:中国大陆
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T34610LSemapimod mesylate;化合物 T34610LSemapimod tetramesylate;Semapimod tetramesylate
Semapimod mesylate is a biochemical.
价 格:¥电议型 号:T34610L产 地:中国大陆