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T11060DMAPTDMAPT,Dimethylamino Parthenolide,
DMAPT (Dimethylamino Parthenol) is a water-soluble analogue of Parthenolide (PTL). It is an orally active NF-κB inhibitor. For cell populations in AML cells, the LD50 is 1.7 μM. It has potential anti-cancer and anti-metastatic effects.
价 格:¥电议型 号:T11060产 地:美洲
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T11943MAPK13-IN-1MAPK13-IN-1
MPAK13-IN-1 is a MAPK13 (p38δ) inhibitor(IC50: 620 nM).?
价 格:¥电议型 号:T11943产 地:美洲
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T12347p38-α MAPK-IN-1p38-α MAPK-IN-1
p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor(IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay).
价 格:¥电议型 号:T12347产 地:美洲
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T12850DilmapimodDilmapimod,SB-681323,GW 681323
Dilmapimod is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.
价 格:¥电议型 号:T12850产 地:美洲
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T12871TalmapimodTalmapimod,SCIO-469,
Talmapimod is a selective, orally active and ATP-competitive inhibitor of p38α(IC50 : 9 nM) .
价 格:¥电议型 号:T12871产 地:美洲
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T12934SMAP-2SMAP-2,DT-1154,
SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. It inhibits the growth of KRAS-mutant lung cancers .
价 格:¥电议型 号:T12934产 地:美洲
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T13451(S)-Mapracorat(S)-Mapracorat,(S)-ZK-245186,(S)-BOL-303242X
(S)-Mapracorat is a selective and less active agonist of glucocorticoid receptor.
价 格:¥电议型 号:T13451产 地:美洲
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T13451LMapracoratMapracorat,ZK-245186,BOL-303242X
Mapracorat is a novel non-steroidal selective agonist of glucocorticoid receptor.
价 格:¥电议型 号:T13451L产 地:美洲
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T15757LimaprostLimaprost,17α,20-dimethyl-δ2-PGE1,ONO1206
Limaprost enhances blood flow and inhibits platelet aggregation. Limaprost is a PGE1 analogue and a potent and orally active vasodilator. Limaprost can be used for pain relief, has antianginal effects, and has the potential for ischaemic symptoms treatmen
价 格:¥电议型 号:T15757产 地:美洲
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T16385OmapatrilatOmapatrilat,BMS-186716,
Omapatrilat is a metalloprotease ACE and NEP dual inhibitor (Ki: 0.64 and 0.45 nM, respectively).
价 格:¥电议型 号:T16385产 地:美洲
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T16424p38 MAPK-IN-1p38 MAPK-IN-1
p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM).
价 格:¥电议型 号:T16424产 地:美洲
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T2277LosmapimodLosmapimod,GW856553X,SB856553
Losmapimod (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).
价 格:¥电议型 号:T2277产 地:美洲
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T2371EmapunilEmapunil,XBD-173,AC-5216
Emapunil is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO.
价 格:¥电议型 号:T2371产 地:美洲
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T2675AS 602801AS 602801,Bentamapimod,
AS 602801(Bentamapimod) is a novel, orally active inhibitor of JNK.
价 格:¥电议型 号:T2675产 地:美洲
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T6089NeflamapimodNeflamapimod,VX-745,
VX-745, a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.
价 格:¥电议型 号:T6089产 地:美洲
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T6277DoramapimodDoramapimod,BIRB 796,
Doramapimod is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.
价 格:¥电议型 号:T6277产 地:美洲
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T83738SMAP 29 (ovine) TFA;化合物 SMAP 29 (ovine) TFASheep Myeloid Antimicrobial Peptide 29;Sheep Myeloid Anti
SMAP 29, a bactericidal antimicrobial peptide and a cleavage product from the C-terminus of an ovine cathelicidin prepropeptide, is effective against P. aeruginosa strain PAO1 in both low- and high-salt conditions, as demonstrated in an energy-dependent luminescence assay with half-maximal effective concentrations (EC50s) of 0.05 and 0.06 ?M, respectively. Additionally, it induces hemolysis in ovine red blood cells in a concentration-dependent manner.
价 格:¥电议型 号:T83738产 地:中国大陆
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T83706BMAP 28 (bovine) TFA;化合物 BMAP 28 (bovine) TFACathelicidin-5 (132-158)|||Bovine Myeloid Antimicrobial
Bovine Myeloid Antimicrobial Peptide (BMAP) 28, a synthetic peptide derived from bovine cathelicidin-5 (amino acids 132-158), exhibits antimicrobial activity against E. coli, S. aureus, MRSA, S. epidermidis, and the fungus C. albicans, with minimum inhibitory concentrations (MICs) of 2, 2, 4, 1, and 8 ?M respectively. At a concentration of 200 nM, BMAP 28 permeabilizes the inner membrane of E. coli, and at 5 ?M, it inhibits herpes simplex virus 1 (HSV-1) replication in Vero 76 cells. Furthermore
价 格:¥电议型 号:T83706产 地:中国大陆
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T81865MAPTAM;化合物 MAPTAMMAPTAM
MAPTAM is an intracellular Ca^2+ (Ca 2+) chelator [1].
价 格:¥电议型 号:T81865产 地:中国大陆
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T80262SMAP-18;化合物 SMAP-18SMAP-18
SMAP-18, an 18-amino acid residue peptide amide, is a biologically active truncated variant of Sheep myeloid antimicrobial peptide-29 (SMAP-29). It retains potent antimicrobial activity against Pseudomonas strains, other Gram-negative bacteria, and multidrug-resistant pathogens. Notably, SMAP-18 exhibits increased cell selectivity relative to the parent peptide SMAP-29 due to its reduced hemolytic activity while maintaining its antimicrobial efficacy.
价 格:¥电议型 号:T80262产 地:中国大陆