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T16424p38 MAPK-IN-1;化合物 T16424p38 MAPK-IN-1
p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM).
价 格:¥电议型 号:T16424产 地:中国大陆
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T16100Balamapimod;化合物 T16100MKI 833;MKI 833
Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.
价 格:¥电议型 号:T16100产 地:中国大陆
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T15757Limaprost;利马前列素17α,20-dimethyl-δ2-PGE1|||OP1206|||ONO1206;17α,20-dimethyl-δ2-PGE1|||利马前列素|||OP1206||
Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost (17α,20-dimethyl-δ2-PGE1) can be used for pain relief, has antianginal effects, and has potential for ischaemic symptoms treatment.
价 格:¥电议型 号:T15757产 地:中国大陆
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T14488Azt-pmap;化合物 T14488Azt-pmap
AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1]. As a nucleoside reverse transcriptase inhibitor (NRTI), AZT-PMPA targets HIV infection effectively[2].
价 格:¥电议型 号:T14488产 地:中国大陆
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T12934SMAP-2;化合物 T12934DT-1154;DT-1154
SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. It inhibits the growth of KRAS-mutant lung cancers .
价 格:¥电议型 号:T12934产 地:中国大陆
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T12871LTalmapimod hydrochloride;化合物 T12871LSCIO-469 hydrochloride;SCIO-469 hydrochloride
Talmapimod hydrochloride is a selective and ATP-competitive p38α inhibitor (IC50: 9 nM). It also shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs.
价 格:¥电议型 号:T12871L产 地:中国大陆
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T12871Talmapimod;他匹莫德SCIO-469;他匹莫德|||SCIO-469
Talmapimod (SCIO-469) is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs.
价 格:¥电议型 号:T12871产 地:中国大陆
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T12850Dilmapimod;度马莫得SB-681323|||GW 681323;SB-681323|||GW 681323|||度马莫得
Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.
价 格:¥电议型 号:T12850产 地:中国大陆
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T12347p38-α MAPK-IN-1;化合物p38-α MAPK-IN-1p38-α MAPK-IN-1
p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor with IC50 of 2300 nM and 5500 nM in EFC displacement assay and HTRF assay,respectively.
价 格:¥电议型 号:T12347产 地:中国大陆
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T11943MAPK13-IN-1;MAPK13抑制剂1MAPK13-IN-1
MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).
价 格:¥电议型 号:T11943产 地:中国大陆
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T11942MAP4K4-IN-3;化合物MAP4K4-IN-3Compound 17;Compound 17
MAP4K4-IN-3 (Compound 17) may be a viable target for antidiabetic agents, a serine/threonine protein kinase.
价 格:¥电议型 号:T11942产 地:中国大陆
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T11241p38 MAPK-IN-2;化合物 T11241p38 MAPK-IN-2
p38 MAPK-IN-2 is an inhibitor of p38 kinase.
价 格:¥电议型 号:T11241产 地:中国大陆
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T11060DMAPT;化合物DMAPTDimethylamino Parthenolide;Dimethylamino Parthenolide
DMAPT (Dimethylamino Parthenolide) is a water-soluble analogue of Parthenolide (PTL). It is an orally active NF-κB inhibitor with an LD50 of 1.7 μM on primary acute myeloid leukemia cells.
价 格:¥电议型 号:T11060产 地:中国大陆
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T10444TAK1/MAP4K2 inhibitor 1;化合物 T10444TAK1/MAP4K2 inhibitor 1
TAK1/MAP4K2 inhibitor 1 is a potent dual inhibitor of TGFβ-activated kinase 1 (TAK1) and MAP4K2 (IC50s: 41.1 nM and 18.2 nM).
价 格:¥电议型 号:T10444产 地:中国大陆
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T0172Maprotiline hydrochloride;盐酸马普替林Maprotiline HCl|||Psymion|||Deprilept|||Ludiomil;Maprotiline HCl|||盐
Maprotiline hydrochloride (Psymion) is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.
价 格:¥电议型 号:T0172产 地:中国大陆