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T70960Maprotiline-d3 hydrochloride；化合物 Maprotiline-d3 hydrochlorideMaprotiline-d3 hydrochloride
Maprotiline-d3 is intended for use as an internal standard for the quantification of maprotiline by GC- or LC-MS. Maprotiline is a tricyclic antidepressant. It binds to the norepinephrine transporter (NET) and is selective for NET over the serotonin and dopamine transporters. Maprotiline also binds to the serotonin (5-HT) receptor subtype 5-HT2A, as well as histamine H1, muscarinic acetylcholine, α1-adrenergic, and dopamine D2 receptors. In vivo, maprotiline inhibits norepinephrine reuptake in r
价 格：￥电议型 号：T70960产 地：中国大陆
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T70638p38-α MAPK-IN-5；化合物 CHF-6297p38-α MAPK-IN-5
P38-α MAPK-IN-5 is a potent inhibitor of p38α, demonstrating inhibitory concentrations (IC50) of 0.1 nM for p38α, 0.2 nM for p38β, 944 nM for p38γ, and 4100 nM for p38δ. It exhibits anti-inflammatory properties and holds potential for research in asthma and chronic obstructive pulmonary disease (COPD).
价 格：￥电议型 号：T70638产 地：中国大陆
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T70253Nordimaprit；化合物 NordimapritNordimaprit
Nordimaprit is effective agonist in the inhibition of lymphocyte activation.
价 格：￥电议型 号：T70253产 地：中国大陆
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T69894MAP3K14-IN-173；化合物 MAP3K14-IN-173MAP3K14-IN-173
MAP3K14-IN-173 is a potent MAP3K14 kinase inhibitor.
价 格：￥电议型 号：T69894产 地：中国大陆
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T6927Pamapimod；帕吡莫德R1503|||Ro4402257；R1503|||帕吡莫德|||Ro4402257
Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38 gamma isoforms.
价 格：￥电议型 号：T6927产 地：中国大陆
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T68971Ormaplatin；化合物 OrmaplatinOrmaplatin
Ormaplatin is a platinum(IV) analogue with antineoplastic activity. Ormaplatin alkylates DNA, forming both inter- and intra-strand platinum-DNA crosslinks, which result in inhibition of DNA replication and transcription and cell-cycle nonspecific cytotoxicity. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
价 格：￥电议型 号：T68971产 地：中国大陆
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T68729Coumaperine；化合物 CoumaperineCoumaperine
Coumaperine is an NF-kB inhibitor.
价 格：￥电议型 号：T68729产 地：中国大陆
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T68297Dilmapimod tosylate；化合物 Dilmapimod tosylateDilmapimod tosylate
Dilmapimod tosylate is a potent p38 mitogen-activated protein kinase (MAPK) inhibitor. It was investigated for its anti-inflammatory effect in non-head injury trauma patients at risk for developing acute respiratory distress syndrome. IL-1β was identified as a gene regulated by dilmapimod that could influence c-reactive protein levels. Dilmapimod had been in phase III clinical trials by GlaxoSmithKline for the treatment of rheumatoid arthritis, neuropathic pain, coronary artery disease (CAD) and
价 格：￥电议型 号：T68297产 地：中国大陆
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T67944p38 MAP Kinase Inhibitor Ⅵ；化合物 p38 MAP Kinase Inhibitor Ⅵp38 MAP Kinase Inhibitor Ⅵ
p38 MAP Kinase Inhibitor Ⅵ is a potent p38 MAP Kinase inhibitor with anti-inflammatory activity.
价 格：￥电议型 号：T67944产 地：中国大陆
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T65377DMAPS；化合物 DMAPSDMAPS
DMAPS is a useful organic compound for research related to life sciences. The catalog number is T65377 and the CAS number is 14933-09-6.
价 格：￥电议型 号：T65377产 地：中国大陆
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T64608Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb #4376R；化合物 Phospho-p44/42 MAPK (Erk1
Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb #4376R is a useful organic compound for research related to life sciences and the catalog number is T64608.
价 格：￥电议型 号：T64608产 地：中国大陆
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T64587p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R；化合物 p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695Rp44
p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R is a useful organic compound for research related to life sciences and the catalog number is T64587.
价 格：￥电议型 号：T64587产 地：中国大陆
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T64256Emapticap pegol；化合物 Emapticap pegolEmapticap pegol
Emapticap pegol is a pro-inflammatory chemokine C-C motif ligand 2 (CCL2) inhibitor. emapticap pegol is also a 40-nucleotide oligonucleotide aptamer that exhibits different forms of Spiegelmers (L-RNA aptamers) in human (NOX-E36) and mouse (mNOX-E36).
价 格：￥电议型 号：T64256产 地：中国大陆
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T64001MAP855；化合物 MAP855MAP855
MAP855 is a potent, selective, orally active, ATP-competitive MEK1/2 kinase inhibitor with an IC50 value of 3 nM for MEK1 ERK2 cascade and a pERKEC50 value of 5 nM. MAP855 exhibits equal inhibition of wild-type and mutant MEK1/2.
价 格：￥电议型 号：T64001产 地：中国大陆
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T63202AP5 sodium；化合物 AP5 sodiumAP5 sodium
AP5 sodium is a selective, potent, orally active GPR40 receptor agonist that exhibits positive allosteric modulation of endogenous ligands (AgoPAM). sodium exhibits potential for the study of type II diabetes.
价 格：￥电议型 号：T63202产 地：中国大陆
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T63119NF-κB/MAPK-IN-1；NF-κB/MAPK抑制剂1NF-κB/MAPK-IN-1
NF-κB/MAPK-IN-1 is a potent dual inhibitor of the NF-κB and MAPK pathways with potential anti-inflammatory activity, inhibition of NO production, and inhibition of LPS-induced activation of iNOS, COX-2, ERΚ and P38. NF-κB/MAPK-IN-1 is used for the prevention and treatment of rheumatoid arthritis (RA).
价 格：￥电议型 号：T63119产 地：中国大陆
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T63067Emprumapimod；化合物 EmprumapimodPF-07265803|||ARRY-371797；PF-07265803|||ARRY-371797
Emprumapimod (PF-07265803) is an orally active and specific inhibitor of mitogen-activated protein kinase p38α MAPK, inhibits LPS-induced production of IL-6, and can be used to study dilated cardiomyopathy induced by the LMNA gene.
价 格：￥电议型 号：T63067产 地：中国大陆
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T6277Doramapimod；达马莫德BIRB 796；BIRB 796|||达马莫德|||度马莫德
Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.
价 格：￥电议型 号：T6277产 地：中国大陆
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T62359TLR4/NF-κB/MAPK-IN-1；化合物 TLR4/NF-κB/MAPK-IN-1TLR4/NF-κB/MAPK-IN-1
TLR4/NF-κB/MAPK-IN-1 is a novel antineuroinflammatory agent that functions by inhibiting the TLR4/NF-κB/MAPK pathways.
价 格：￥电议型 号：T62359产 地：中国大陆
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T61803p38 MAPK-IN-3；化合物 p38 MAPK-IN-3p38 MAPK-IN-3
p38 MAPK-IN-3 (Compound 2c) is a potent inhibitor of p38α MAPK, displaying antitumor properties by promoting apoptosis and increasing reactive oxygen species (ROS) production [1].
价 格：￥电议型 号：T61803产 地：中国大陆
